CRCGN012_HEPG2_24H:F14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description adipamide 20.1 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

68 genes differentially expressed following the CRCGN012_HEPG2_24H:F14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 7.23078
CHN1 chimerin 1 5.45294
SMIM40 small integral membrane protein 40 4.73033
SYNE2 spectrin repeat containing, nuclear envelope 2 4.70773
PPARG peroxisome proliferator-activated receptor gamma 4.5424
UBQLN2 ubiquilin 2 4.21367
DYNLT3 dynein, light chain, Tctex-type 3 4.20305
ATP11B ATPase, class VI, type 11B 4.18341
JADE2 jade family PHD finger 2 4.12629
PNKP polynucleotide kinase 3'-phosphatase 4.00209
RPP38 ribonuclease P/MRP 38kDa subunit 3.97718
EPHB2 EPH receptor B2 3.92056
LOC122526780 uncharacterized LOC122526780 3.45611
WDTC1 WD and tetratricopeptide repeats 1 3.16344
GPER1 G protein-coupled estrogen receptor 1 2.9867
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.98526
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 2.94251
GSTZ1 glutathione S-transferase zeta 1 2.90075
PMM2 phosphomannomutase 2 2.89656
FZD7 frizzled class receptor 7 2.85168
ABHD4 abhydrolase domain containing 4 2.58488
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.58262
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2.58251
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.42669
CRTAP cartilage associated protein 2.38928
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.30458
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.23336
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 2.16539
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.14979
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 2.07709
NINL ninein-like 2.03749
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 2.02974

decreased expression

Symbol Name Standardized Value
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -8.42176
SLC35F2 solute carrier family 35, member F2 -4.91346
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -4.74091
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -4.62974
TRIB3 tribbles pseudokinase 3 -4.52573
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -4.45499
NUP85 nucleoporin 85kDa -4.41709
ARID5B AT rich interactive domain 5B (MRF1-like) -4.40269
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -4.19775
CCDC86 coiled-coil domain containing 86 -4.09282
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.81141
FBXL12 F-box and leucine-rich repeat protein 12 -3.70682
MRPS7 mitochondrial ribosomal protein S7 -3.05956
RPS5 ribosomal protein S5 -2.95595
CAB39 calcium binding protein 39 -2.95105
MRPL58 mitochondrial ribosomal protein L58 -2.52299
TGFB3 transforming growth factor, beta 3 -2.48898
CRK v-crk avian sarcoma virus CT10 oncogene homolog -2.47916
CCNB2 cyclin B2 -2.45911
GDF15 growth differentiation factor 15 -2.41409
TMEM94 transmembrane protein 94 -2.2984
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -2.26575
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.2518
ZMIZ1 zinc finger, MIZ-type containing 1 -2.24333
CASKIN2 CASK interacting protein 2 -2.18323
SLC46A3 solute carrier family 46, member 3 -2.16587
RBM15 RNA binding motif protein 15 -2.14385
LOC107986346 mitochondrial import receptor subunit TOM7 homolog -2.13965
SCCPDH saccharopine dehydrogenase (putative) -2.13178
CERS2 ceramide synthase 2 -2.10877
TLCD3A TLC domain containing 3A -2.1049
CDC25B cell division cycle 25B -2.085
KCTD2 potassium channel tetramerization domain containing 2 -2.0709
AVL9 AVL9 homolog (S. cerevisiase) -2.03868
ITGB1BP1 integrin beta 1 binding protein 1 -2.03684
UGDH UDP-glucose 6-dehydrogenase -2.00814