| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | adipamide 20.1 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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68 genes differentially expressed following the CRCGN012_HEPG2_24H:F14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 7.23078 |
| CHN1 | chimerin 1 | 5.45294 |
| SMIM40 | small integral membrane protein 40 | 4.73033 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 4.70773 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.5424 |
| UBQLN2 | ubiquilin 2 | 4.21367 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 4.20305 |
| ATP11B | ATPase, class VI, type 11B | 4.18341 |
| JADE2 | jade family PHD finger 2 | 4.12629 |
| PNKP | polynucleotide kinase 3'-phosphatase | 4.00209 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 3.97718 |
| EPHB2 | EPH receptor B2 | 3.92056 |
| LOC122526780 | uncharacterized LOC122526780 | 3.45611 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 3.16344 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.9867 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.98526 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 2.94251 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.90075 |
| PMM2 | phosphomannomutase 2 | 2.89656 |
| FZD7 | frizzled class receptor 7 | 2.85168 |
| ABHD4 | abhydrolase domain containing 4 | 2.58488 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 2.58262 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 2.58251 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 2.42669 |
| CRTAP | cartilage associated protein | 2.38928 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.30458 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.23336 |
| SLC9B2 | solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 | 2.16539 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 2.14979 |
| LAMTOR3 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 | 2.07709 |
| NINL | ninein-like | 2.03749 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 2.02974 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -8.42176 |
| SLC35F2 | solute carrier family 35, member F2 | -4.91346 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.74091 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.62974 |
| TRIB3 | tribbles pseudokinase 3 | -4.52573 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -4.45499 |
| NUP85 | nucleoporin 85kDa | -4.41709 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -4.40269 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.19775 |
| CCDC86 | coiled-coil domain containing 86 | -4.09282 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.81141 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -3.70682 |
| MRPS7 | mitochondrial ribosomal protein S7 | -3.05956 |
| RPS5 | ribosomal protein S5 | -2.95595 |
| CAB39 | calcium binding protein 39 | -2.95105 |
| MRPL58 | mitochondrial ribosomal protein L58 | -2.52299 |
| TGFB3 | transforming growth factor, beta 3 | -2.48898 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -2.47916 |
| CCNB2 | cyclin B2 | -2.45911 |
| GDF15 | growth differentiation factor 15 | -2.41409 |
| TMEM94 | transmembrane protein 94 | -2.2984 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | -2.26575 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.2518 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.24333 |
| CASKIN2 | CASK interacting protein 2 | -2.18323 |
| SLC46A3 | solute carrier family 46, member 3 | -2.16587 |
| RBM15 | RNA binding motif protein 15 | -2.14385 |
| LOC107986346 | mitochondrial import receptor subunit TOM7 homolog | -2.13965 |
| SCCPDH | saccharopine dehydrogenase (putative) | -2.13178 |
| CERS2 | ceramide synthase 2 | -2.10877 |
| TLCD3A | TLC domain containing 3A | -2.1049 |
| CDC25B | cell division cycle 25B | -2.085 |
| KCTD2 | potassium channel tetramerization domain containing 2 | -2.0709 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -2.03868 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.03684 |
| UGDH | UDP-glucose 6-dehydrogenase | -2.00814 |