CRCGN012_HEPG2_24H:F16 Gene Set
Genes
43 genes differentially expressed following the CRCGN012_HEPG2_24H:F16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
9.47741
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
7.38449
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
5.10952
|
|
NOTCH1
|
notch 1
|
4.61344
|
|
CHN1
|
chimerin 1
|
4.14204
|
|
MOK
|
MOK protein kinase
|
3.91331
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.40389
|
|
RPL39L
|
ribosomal protein L39-like
|
3.16157
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.69698
|
|
HOXA10
|
homeobox A10
|
2.63958
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.60786
|
|
UBQLN2
|
ubiquilin 2
|
2.60234
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.4551
|
|
CBR3
|
carbonyl reductase 3
|
2.36631
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
2.33278
|
|
JADE2
|
jade family PHD finger 2
|
2.17016
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.14902
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
2.13796
|
|
CHEK2
|
checkpoint kinase 2
|
2.12758
|
|
ABCA8
|
ATP-binding cassette, sub-family A (ABC1), member 8
|
2.11637
|
|
CSK
|
c-src tyrosine kinase
|
2.11478
|
|
INPP5E
|
inositol polyphosphate-5-phosphatase, 72 kDa
|
2.1044
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.09317
|
|
SLC25A20
|
solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
|
2.09244
|
|
CGRRF1
|
cell growth regulator with ring finger domain 1
|
2.05551
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.01885
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-5.49907
|
|
ENOPH1
|
enolase-phosphatase 1
|
-4.46801
|
|
LDHD
|
lactate dehydrogenase D
|
-4.46065
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.27277
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.80298
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.79951
|
|
TSPAN4
|
tetraspanin 4
|
-3.18121
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.92786
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.88072
|
|
GDF15
|
growth differentiation factor 15
|
-2.75013
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.64906
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.64395
|
|
CCDC86
|
coiled-coil domain containing 86
|
-2.5169
|
|
PDHX
|
pyruvate dehydrogenase complex, component X
|
-2.13525
|
|
CAPN6
|
calpain 6
|
-2.09695
|
|
COL9A1
|
collagen, type IX, alpha 1
|
-2.00658
|
|
GNAS
|
GNAS complex locus
|
-2.00116
|
