| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | adipamide 2.51 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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68 genes differentially expressed following the CRCGN012_HEPG2_24H:F17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GSTZ1 | glutathione S-transferase zeta 1 | 8.17651 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 6.91102 |
| ADRB2 | adrenoceptor beta 2, surface | 6.54315 |
| LCN2 | lipocalin 2 | 6.06141 |
| MYLK | myosin light chain kinase | 4.27667 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 3.92233 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.86144 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.70584 |
| RPL39L | ribosomal protein L39-like | 3.68527 |
| MAMLD1 | mastermind-like domain containing 1 | 3.64971 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 3.63585 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.57776 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.2072 |
| PLSCR1 | phospholipid scramblase 1 | 3.13529 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 2.9139 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 2.90476 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 2.88453 |
| E2F2 | E2F transcription factor 2 | 2.77002 |
| MOK | MOK protein kinase | 2.6904 |
| UBQLN2 | ubiquilin 2 | 2.66282 |
| EVL | Enah/Vasp-like | 2.63252 |
| NOTCH1 | notch 1 | 2.31325 |
| COPS7A | COP9 signalosome subunit 7A | 2.26761 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.22791 |
| EPHA3 | EPH receptor A3 | 2.22593 |
| COX6A1 | cytochrome c oxidase subunit VIa polypeptide 1 | 2.16286 |
| LOC122526780 | uncharacterized LOC122526780 | 2.13931 |
| HSPA1A | heat shock 70kDa protein 1A | 2.13208 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.11834 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 2.00081 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KDM3A | lysine (K)-specific demethylase 3A | -7.1392 |
| CDC20 | cell division cycle 20 | -7.00991 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -6.02902 |
| CHMP4B | charged multivesicular body protein 4B | -5.68268 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.12604 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.85047 |
| UGDH | UDP-glucose 6-dehydrogenase | -3.64326 |
| EGF | epidermal growth factor | -3.62918 |
| DSG2 | desmoglein 2 | -3.40918 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | -3.33333 |
| MRPS2 | mitochondrial ribosomal protein S2 | -3.18056 |
| NVL | nuclear VCP-like | -3.14266 |
| CD320 | CD320 molecule | -3.08312 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.02595 |
| TUBB6 | tubulin, beta 6 class V | -2.93233 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.93122 |
| ADI1 | acireductone dioxygenase 1 | -2.91597 |
| CCNB1 | cyclin B1 | -2.75591 |
| MANBA | mannosidase, beta A, lysosomal | -2.57529 |
| CD58 | CD58 molecule | -2.53793 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -2.35596 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -2.31662 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -2.30073 |
| PDLIM1 | PDZ and LIM domain 1 | -2.26753 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | -2.26327 |
| HOXA2 | homeobox A2 | -2.25609 |
| ZMYM6 | zinc finger, MYM-type 6 | -2.18177 |
| ANKRD10 | ankyrin repeat domain 10 | -2.17017 |
| PRPF4 | pre-mRNA processing factor 4 | -2.14107 |
| USP3 | ubiquitin specific peptidase 3 | -2.12659 |
| YME1L1 | YME1-like 1 ATPase | -2.12412 |
| RAI14 | retinoic acid induced 14 | -2.0741 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -2.07092 |
| EFS | embryonal Fyn-associated substrate | -2.05643 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.02398 |
| EPHB2 | EPH receptor B2 | -2.01095 |
| CDC25B | cell division cycle 25B | -2.00247 |
| CHKB | choline kinase beta | -2.00075 |
