CRCGN012_HEPG2_24H:F18 Gene Set
Genes
50 genes differentially expressed following the CRCGN012_HEPG2_24H:F18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
5.13703
|
|
CSK
|
c-src tyrosine kinase
|
5.05237
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.01116
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
4.43009
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
4.25126
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
4.23959
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
4.16277
|
|
MICALL1
|
MICAL-like 1
|
4.15943
|
|
CBR3
|
carbonyl reductase 3
|
4.0684
|
|
STIMATE
|
STIM activating enhancer
|
4.03522
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
3.92446
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.81594
|
|
E2F2
|
E2F transcription factor 2
|
3.68612
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
3.36073
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
3.19808
|
|
MKNK1
|
MAP kinase interacting serine/threonine kinase 1
|
3.05455
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.9046
|
|
ADO
|
2-aminoethanethiol (cysteamine) dioxygenase
|
2.79681
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.63611
|
|
FZD7
|
frizzled class receptor 7
|
2.536
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
2.44597
|
|
JADE2
|
jade family PHD finger 2
|
2.43705
|
|
EPN2
|
epsin 2
|
2.39687
|
|
RALGDS
|
ral guanine nucleotide dissociation stimulator
|
2.25969
|
|
ZNF761
|
zinc finger protein 761
|
2.25094
|
|
GATA3
|
GATA binding protein 3
|
2.20244
|
|
ZNF200
|
zinc finger protein 200
|
2.12971
|
|
SIAH2
|
siah E3 ubiquitin protein ligase 2
|
2.10846
|
|
ATAD2B
|
ATPase family, AAA domain containing 2B
|
2.05411
|
|
ANO10
|
anoctamin 10
|
2.0067
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-5.73226
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-5.2894
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.89467
|
|
YME1L1
|
YME1-like 1 ATPase
|
-4.03409
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.79998
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.65399
|
|
GNAS
|
GNAS complex locus
|
-3.63181
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.61037
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.50619
|
|
HSPB1
|
heat shock 27kDa protein 1
|
-3.38306
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.18125
|
|
SPAG4
|
sperm associated antigen 4
|
-3.1497
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.06547
|
|
TXNRD1
|
thioredoxin reductase 1
|
-2.50161
|
|
CCNB2
|
cyclin B2
|
-2.27916
|
|
PPOX
|
protoporphyrinogen oxidase
|
-2.26239
|
|
ERC2
|
ELKS/RAB6-interacting/CAST family member 2
|
-2.25901
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.22006
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-2.06813
|
|
ARHGAP15
|
Rho GTPase activating protein 15
|
-2.05638
|
