CRCGN012_HEPG2_24H:F22 Gene Set
Genes
50 genes differentially expressed following the CRCGN012_HEPG2_24H:F22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CSK
|
c-src tyrosine kinase
|
8.21203
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
5.39492
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.95896
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.84255
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
4.68095
|
|
ATP11B
|
ATPase, class VI, type 11B
|
4.03982
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
3.97804
|
|
STK10
|
serine/threonine kinase 10
|
3.94599
|
|
NFIL3
|
nuclear factor, interleukin 3 regulated
|
3.91624
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.91391
|
|
PRR15L
|
proline rich 15-like
|
3.74259
|
|
CYCS
|
cytochrome c, somatic
|
3.23405
|
|
SCYL3
|
SCY1-like 3 (S. cerevisiae)
|
3.12497
|
|
IDE
|
insulin-degrading enzyme
|
3.00198
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
2.97649
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
2.75015
|
|
MPC2
|
mitochondrial pyruvate carrier 2
|
2.53819
|
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
2.40687
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
2.35623
|
|
FSD1
|
fibronectin type III and SPRY domain containing 1
|
2.16423
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.11283
|
|
DRAP1
|
DR1-associated protein 1 (negative cofactor 2 alpha)
|
2.06355
|
|
AHR
|
aryl hydrocarbon receptor
|
2.03483
|
|
PTEN
|
phosphatase and tensin homolog
|
2.02964
|
|
TBPL1
|
TBP-like 1
|
2.01997
|
|
SLC2A6
|
solute carrier family 2 (facilitated glucose transporter), member 6
|
2.0132
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-5.14262
|
|
RPIA
|
ribose 5-phosphate isomerase A
|
-4.63839
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-4.3693
|
|
TRIB3
|
tribbles pseudokinase 3
|
-4.18136
|
|
EGF
|
epidermal growth factor
|
-4.16474
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.84249
|
|
GNAS
|
GNAS complex locus
|
-3.70798
|
|
GDF15
|
growth differentiation factor 15
|
-3.35009
|
|
YME1L1
|
YME1-like 1 ATPase
|
-3.33206
|
|
ZW10
|
zw10 kinetochore protein
|
-2.91969
|
|
TCERG1
|
transcription elongation regulator 1
|
-2.87639
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
-2.6172
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.5864
|
|
CLOCK
|
clock circadian regulator
|
-2.40151
|
|
CANT1
|
calcium activated nucleotidase 1
|
-2.37507
|
|
CADPS2
|
Ca++-dependent secretion activator 2
|
-2.20623
|
|
DEFA4
|
defensin, alpha 4, corticostatin
|
-2.18831
|
|
UCMA
|
upper zone of growth plate and cartilage matrix associated
|
-2.16709
|
|
AIFM2
|
apoptosis-inducing factor, mitochondrion-associated, 2
|
-2.16226
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.15655
|
|
APOD
|
apolipoprotein D
|
-2.07147
|
|
CHAMP1
|
chromosome alignment maintaining phosphoprotein 1
|
-2.05897
|
|
CEACAM8
|
carcinoembryonic antigen-related cell adhesion molecule 8
|
-2.03066
|
|
BPI
|
bactericidal/permeability-increasing protein
|
-2.02368
|
