CRCGN012_HEPG2_24H:F23 Gene Set
Genes
48 genes differentially expressed following the CRCGN012_HEPG2_24H:F23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
10.0
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
6.5892
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.14946
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.09646
|
|
KLHL21
|
kelch-like family member 21
|
3.94433
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.71641
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.55011
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.14005
|
|
MAP7
|
microtubule-associated protein 7
|
2.88734
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
2.86929
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.65085
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.63407
|
|
IDE
|
insulin-degrading enzyme
|
2.47421
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.47363
|
|
CDC45
|
cell division cycle 45
|
2.46108
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
2.4155
|
|
LCN2
|
lipocalin 2
|
2.3548
|
|
EPHB2
|
EPH receptor B2
|
2.33695
|
|
CARM1
|
coactivator-associated arginine methyltransferase 1
|
2.24522
|
|
SOCS6
|
suppressor of cytokine signaling 6
|
2.17802
|
|
CRYL1
|
crystallin, lambda 1
|
2.141
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.10486
|
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
2.10081
|
|
HOXA10-HOXA9
|
HOXA10-HOXA9 readthrough
|
2.07214
|
|
TLR4
|
toll-like receptor 4
|
2.06571
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-7.37203
|
|
LAP3
|
leucine aminopeptidase 3
|
-3.94901
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-3.91027
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.82487
|
|
LDHD
|
lactate dehydrogenase D
|
-3.81406
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-3.78037
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.6699
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.6381
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-3.46486
|
|
GDF15
|
growth differentiation factor 15
|
-3.37395
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.89388
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.81069
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.76267
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.57471
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.48359
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.31166
|
|
ERO1A
|
endoplasmic reticulum oxidoreductase 1 alpha
|
-2.30802
|
|
NDC80
|
NDC80 kinetochore complex component
|
-2.30446
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.29059
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.21512
|
|
TSPAN4
|
tetraspanin 4
|
-2.05938
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.02457
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.00014
|
