CRCGN012_HEPG2_24H:F24 Gene Set
Genes
46 genes differentially expressed following the CRCGN012_HEPG2_24H:F24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
7.96654
|
|
E2F2
|
E2F transcription factor 2
|
4.96781
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.91448
|
|
MYLK
|
myosin light chain kinase
|
4.68737
|
|
RPL39L
|
ribosomal protein L39-like
|
4.62062
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.44215
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.33105
|
|
NOTCH1
|
notch 1
|
4.11879
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
4.10361
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
3.88394
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.692
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.43565
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.109
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.93406
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.76016
|
|
FPGS
|
folylpolyglutamate synthase
|
2.66449
|
|
CCNH
|
cyclin H
|
2.49817
|
|
GPATCH8
|
G patch domain containing 8
|
2.44718
|
|
JADE2
|
jade family PHD finger 2
|
2.3533
|
|
NENF
|
neudesin neurotrophic factor
|
2.34155
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.28841
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.21557
|
|
PCNA
|
proliferating cell nuclear antigen
|
2.20104
|
|
FAM168B
|
family with sequence similarity 168, member B
|
2.17098
|
|
STXBP2
|
syntaxin binding protein 2
|
2.10421
|
|
CLTC
|
clathrin, heavy chain (Hc)
|
2.10264
|
|
BAHCC1
|
BAH domain and coiled-coil containing 1
|
2.04147
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-8.74677
|
|
ZNF586
|
zinc finger protein 586
|
-5.02724
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.70425
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.63696
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.63191
|
|
EGF
|
epidermal growth factor
|
-3.52204
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.2377
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.22813
|
|
SCAND1
|
SCAN domain containing 1
|
-2.68063
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-2.62209
|
|
TSEN2
|
TSEN2 tRNA splicing endonuclease subunit
|
-2.42223
|
|
TRIM5
|
tripartite motif containing 5
|
-2.32508
|
|
PHACTR4
|
phosphatase and actin regulator 4
|
-2.26981
|
|
PPIB
|
peptidylprolyl isomerase B (cyclophilin B)
|
-2.1727
|
|
BBS7
|
Bardet-Biedl syndrome 7
|
-2.15661
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.14425
|
|
ASB8
|
ankyrin repeat and SOCS box containing 8
|
-2.04121
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.02263
|
|
MAGT1
|
magnesium transporter 1
|
-2.00432
|
