CRCGN012_HEPG2_24H:G06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description rotenone 1.26 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

479 genes differentially expressed following the CRCGN012_HEPG2_24H:G06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
UBQLN2 ubiquilin 2 10.0
KIFBP kinesin family binding protein 9.51688
INPP1 inositol polyphosphate-1-phosphatase 8.86946
TIMP2 TIMP metallopeptidase inhibitor 2 8.33359
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 7.5362
TXNRD1 thioredoxin reductase 1 7.1366
LCN2 lipocalin 2 7.11212
MVP major vault protein 6.99785
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 6.71065
VAT1 vesicle amine transport 1 6.65434
IER3 immediate early response 3 6.49775
TRIB3 tribbles pseudokinase 3 6.3934
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 6.17232
BZW2 basic leucine zipper and W2 domains 2 6.1497
EGR1 early growth response 1 6.01852
STX1A syntaxin 1A (brain) 5.93147
FOSL1 FOS-like antigen 1 5.60682
SQSTM1 sequestosome 1 5.55622
CDPF1 cysteine-rich, DPF motif domain containing 1 5.43688
LRP10 low density lipoprotein receptor-related protein 10 5.34163
FHL2 four and a half LIM domains 2 4.88451
SQOR sulfide quinone oxidoreductase 4.82129
NANOS3 nanos homolog 3 (Drosophila) 4.78211
PNKP polynucleotide kinase 3'-phosphatase 4.72824
ZFP36 ZFP36 ring finger protein 4.62812
NPC1 Niemann-Pick disease, type C1 4.59474
PRKCQ protein kinase C, theta 4.5908
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 4.54825
CASC3 cancer susceptibility candidate 3 4.53897
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 4.43619
MYC v-myc avian myelocytomatosis viral oncogene homolog 4.40254
PPARG peroxisome proliferator-activated receptor gamma 4.38805
GPER1 G protein-coupled estrogen receptor 1 4.37404
IGFBP3 insulin-like growth factor binding protein 3 4.36089
TOMM34 translocase of outer mitochondrial membrane 34 4.34233
CAB39 calcium binding protein 39 4.20377
ACOT9 acyl-CoA thioesterase 9 4.18287
IL4R interleukin 4 receptor 4.17214
DSG2 desmoglein 2 4.02224
NR1H2 nuclear receptor subfamily 1, group H, member 2 3.94121
TRIB1 tribbles pseudokinase 1 3.9236
RALB v-ral simian leukemia viral oncogene homolog B 3.87777
SOX4 SRY (sex determining region Y)-box 4 3.86903
CYCS cytochrome c, somatic 3.77686
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 3.61147
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 3.61064
ISOC1 isochorismatase domain containing 1 3.56334
AARS1 alanyl-tRNA synthetase 1 3.49374
PRKCD protein kinase C, delta 3.4821
DNM1 dynamin 1 3.47838
GSTZ1 glutathione S-transferase zeta 1 3.46395
PCDHB11 protocadherin beta 11 3.42206
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.40432
TERF2IP telomeric repeat binding factor 2, interacting protein 3.39296
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 3.35488
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 3.33781
MACF1 microtubule-actin crosslinking factor 1 3.3001
MICALL1 MICAL-like 1 3.27984
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 3.26845
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 3.20511
PHKA1 phosphorylase kinase, alpha 1 (muscle) 3.18706
DUSP6 dual specificity phosphatase 6 3.18558
KLHL21 kelch-like family member 21 3.15563
MAMLD1 mastermind-like domain containing 1 3.12191
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 3.11925
MYH9 myosin, heavy chain 9, non-muscle 3.10451
UBR4 ubiquitin protein ligase E3 component n-recognin 4 3.09433
TBC1D15 TBC1 domain family, member 15 3.08396
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 3.04745
NUP58 nucleoporin 58 3.04471
PYGB phosphorylase, glycogen; brain 3.04044
GFOD1 glucose-fructose oxidoreductase domain containing 1 3.01487
CSNK1E casein kinase 1, epsilon 2.98605
CNPY3 canopy FGF signaling regulator 3 2.96415
GLRX glutaredoxin (thioltransferase) 2.95597
PPARD peroxisome proliferator-activated receptor delta 2.95261
MBNL1 muscleblind-like splicing regulator 1 2.93164
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.92218
SKIC2 SKI2 subunit of superkiller complex 2.91617
PTPN12 protein tyrosine phosphatase, non-receptor type 12 2.90597
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 2.89621
TICAM1 toll-like receptor adaptor molecule 1 2.88832
KDM5C lysine (K)-specific demethylase 5C 2.8816
NMU neuromedin U 2.84579
ALAS1 5'-aminolevulinate synthase 1 2.83388
CHN1 chimerin 1 2.83307
SAA2 serum amyloid A2 2.80901
SUN2 Sad1 and UNC84 domain containing 2 2.8076
TXNL4B thioredoxin-like 4B 2.80111
CDK7 cyclin-dependent kinase 7 2.7996
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.79588
GDI1 GDP dissociation inhibitor 1 2.79415
DDIT4 DNA-damage-inducible transcript 4 2.78595
YARS1 tyrosyl-tRNA synthetase 1 2.77129
MBNL2 muscleblind-like splicing regulator 2 2.75412
SMAD3 SMAD family member 3 2.75312
MEST mesoderm specific transcript 2.75054
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.71361
PXDC1 PX domain containing 1 2.68891
TP53BP2 tumor protein p53 binding protein 2 2.67459
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 2.67237
BIRC3 baculoviral IAP repeat containing 3 2.66356
JOSD1 Josephin domain containing 1 2.64706
CHIC2 cysteine-rich hydrophobic domain 2 2.64415
PLK3 polo-like kinase 3 2.63027
BLVRA biliverdin reductase A 2.61638
POLH polymerase (DNA directed), eta 2.61544
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 2.61485
FBXO7 F-box protein 7 2.61393
ZYX zyxin 2.59965
C2CD2L C2CD2-like 2.59168
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 2.59026
BYSL bystin-like 2.58701
MT1G metallothionein 1G 2.58248
UBA1 ubiquitin-like modifier activating enzyme 1 2.5732
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 2.56884
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 2.55765
PHC2 polyhomeotic homolog 2 (Drosophila) 2.54921
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.54718
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 2.54663
MGLL monoglyceride lipase 2.53578
ITGB5 integrin, beta 5 2.53159
SYNGR3 synaptogyrin 3 2.52951
OSGIN2 oxidative stress induced growth inhibitor family member 2 2.52646
SARS1 seryl-tRNA synthetase 1 2.52056
CLIP4 CAP-GLY domain containing linker protein family, member 4 2.51408
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.51102
WDTC1 WD and tetratricopeptide repeats 1 2.50525
GIPC1 GIPC PDZ domain containing family, member 1 2.48961
H2BC6 H2B clustered histone 6 2.4746
GFPT1 glutamine--fructose-6-phosphate transaminase 1 2.46738
STAP2 signal transducing adaptor family member 2 2.46623
GRB10 growth factor receptor-bound protein 10 2.46249
MAG myelin associated glycoprotein 2.4613
NPDC1 neural proliferation, differentiation and control, 1 2.45655
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 2.45008
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 2.44885
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 2.44832
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 2.4453
CCDC68 coiled-coil domain containing 68 2.43444
BIRC2 baculoviral IAP repeat containing 2 2.42867
CAMTA2 calmodulin binding transcription activator 2 2.42851
PDGFA platelet-derived growth factor alpha polypeptide 2.41974
NT5M 5',3'-nucleotidase, mitochondrial 2.41072
TGM5 transglutaminase 5 2.37909
PDZD8 PDZ domain containing 8 2.37905
IL37 interleukin 37 2.37484
FLNB filamin B, beta 2.37304
MAP1S microtubule-associated protein 1S 2.36939
SH3GLB1 SH3-domain GRB2-like endophilin B1 2.36482
TMEM184B transmembrane protein 184B 2.36218
EIF3D eukaryotic translation initiation factor 3, subunit D 2.36048
ATG2A autophagy related 2A 2.35002
MMP1 matrix metallopeptidase 1 2.35001
AGFG1 ArfGAP with FG repeats 1 2.34234
ST18 suppression of tumorigenicity 18, zinc finger 2.32856
EPN2 epsin 2 2.30556
MAST2 microtubule associated serine/threonine kinase 2 2.29876
TRIM13 tripartite motif containing 13 2.29416
ELOVL4 ELOVL fatty acid elongase 4 2.29327
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.29194
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 2.29111
ZNF358 zinc finger protein 358 2.27836
TESK1 testis-specific kinase 1 2.27667
FEZF2 FEZ family zinc finger 2 2.27124
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 2.26484
ABHD4 abhydrolase domain containing 4 2.25862
HTRA1 HtrA serine peptidase 1 2.25193
E2F2 E2F transcription factor 2 2.24336
ITGAV integrin, alpha V 2.23889
PRAF2 PRA1 domain family, member 2 2.2322
GARS1 glycyl-tRNA synthetase 1 2.23102
IL7R interleukin 7 receptor 2.22326
NXF3 nuclear RNA export factor 3 2.2154
KDM6B lysine (K)-specific demethylase 6B 2.20739
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.20724
WDR13 WD repeat domain 13 2.20559
LIF leukemia inhibitory factor 2.20261
VGLL4 vestigial-like family member 4 2.19885
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 2.18723
ATG14 autophagy related 14 2.1785
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 2.17222
IGFBP1 insulin-like growth factor binding protein 1 2.17063
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 2.16518
PTPN14 protein tyrosine phosphatase, non-receptor type 14 2.15925
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 2.14589
PHLDA2 pleckstrin homology-like domain, family A, member 2 2.13804
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 2.1369
LGALS8 lectin, galactoside-binding, soluble, 8 2.13421
BCAR3 breast cancer anti-estrogen resistance 3 2.13253
ADGRE5 adhesion G protein-coupled receptor E5 2.1273
SF3A2 splicing factor 3a, subunit 2, 66kDa 2.11923
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 2.11583
APMAP adipocyte plasma membrane associated protein 2.11554
CYTH2 cytohesin 2 2.11229
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 2.1106
MT1H metallothionein 1H 2.1087
KDM5A lysine (K)-specific demethylase 5A 2.1087
ELOVL5 ELOVL fatty acid elongase 5 2.10795
MIER2 mesoderm induction early response 1, family member 2 2.10308
ARHGAP22 Rho GTPase activating protein 22 2.1005
ZMIZ1 zinc finger, MIZ-type containing 1 2.09398
MAP7D1 MAP7 domain containing 1 2.08607
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2.08234
DOCK5 dedicator of cytokinesis 5 2.08054
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 2.0727
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein 2.07013
SDC4 syndecan 4 2.06551
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 2.06344
DVL1 dishevelled segment polarity protein 1 2.06251
GPATCH8 G patch domain containing 8 2.06101
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 2.06039
STXBP2 syntaxin binding protein 2 2.05988
DYNLT3 dynein, light chain, Tctex-type 3 2.05894
ZFP69B ZFP69 zinc finger protein B 2.05594
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 2.05525
FSCN1 fascin actin-bundling protein 1 2.05364
FAM222B family with sequence similarity 222, member B 2.0515
MOG myelin oligodendrocyte glycoprotein 2.05011
KLF7 Kruppel-like factor 7 (ubiquitous) 2.0465
H2BC21 H2B clustered histone 21 2.04318
CCL20 chemokine (C-C motif) ligand 20 2.03915
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 2.0388
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 2.038
EPS8L3 EPS8-like 3 2.03782
IL18R1 interleukin 18 receptor 1 2.03605
IL18RAP interleukin 18 receptor accessory protein 2.02955
BTG1 B-cell translocation gene 1, anti-proliferative 2.0281
WDR44 WD repeat domain 44 2.02719
SCT secretin 2.02233
BABAM2 BRISC and BRCA1 A complex member 2 2.01942
CCDC57 coiled-coil domain containing 57 2.01236
STBD1 starch binding domain 1 2.01092
GADD45A growth arrest and DNA-damage-inducible, alpha 2.00787
CTTN cortactin 2.00328
DIPK1A divergent protein kinase domain 1A 2.00272
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.00201

decreased expression

Symbol Name Standardized Value
LDHD lactate dehydrogenase D -10.0
NT5DC2 5'-nucleotidase domain containing 2 -10.0
TCTN1 tectonic family member 1 -9.04026
B4GAT1 beta-1,4-glucuronyltransferase 1 -8.7076
MELK maternal embryonic leucine zipper kinase -7.06062
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -6.8869
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -6.71716
CCNB1 cyclin B1 -6.57635
RPS4Y1 ribosomal protein S4, Y-linked 1 -6.21328
AURKB aurora kinase B -6.04852
BLCAP bladder cancer associated protein -6.03483
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -5.97082
DERA deoxyribose-phosphate aldolase (putative) -5.84677
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -5.78125
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -5.65366
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -5.60485
CDK1 cyclin-dependent kinase 1 -5.49502
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -5.42756
GNAS GNAS complex locus -5.20597
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -5.16257
PGAM4 phosphoglycerate mutase family member 4 -5.13221
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -4.91957
PSRC1 proline/serine-rich coiled-coil 1 -4.9192
SOAT2 sterol O-acyltransferase 2 -4.91539
PGM1 phosphoglucomutase 1 -4.82439
STMN1 stathmin 1 -4.74782
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -4.56017
CCNA2 cyclin A2 -4.47003
GTF2A2 general transcription factor IIA, 2, 12kDa -4.46957
THAP11 THAP domain containing 11 -4.46884
ALDOC aldolase C, fructose-bisphosphate -4.44386
TMEM109 transmembrane protein 109 -4.39957
HSPB1 heat shock 27kDa protein 1 -4.34735
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -4.30766
POLR1A polymerase (RNA) I polypeptide A, 194kDa -4.27801
NUP85 nucleoporin 85kDa -4.17433
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -4.15166
HAT1 histone acetyltransferase 1 -3.96445
CDK4 cyclin-dependent kinase 4 -3.9153
ICAM3 intercellular adhesion molecule 3 -3.91393
ZW10 zw10 kinetochore protein -3.86711
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.84676
CDC20 cell division cycle 20 -3.83679
RFC2 replication factor C (activator 1) 2, 40kDa -3.77233
CASP7 caspase 7, apoptosis-related cysteine peptidase -3.7197
BIRC5 baculoviral IAP repeat containing 5 -3.67303
RNASE7 ribonuclease, RNase A family, 7 -3.66625
ZNF274 zinc finger protein 274 -3.64194
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -3.6351
LBR lamin B receptor -3.62842
TOP2A topoisomerase (DNA) II alpha 170kDa -3.61218
COG7 component of oligomeric golgi complex 7 -3.57449
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -3.55018
HMGA2 high mobility group AT-hook 2 -3.46189
CHEK2 checkpoint kinase 2 -3.39496
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -3.39401
ASF1B anti-silencing function 1B histone chaperone -3.38662
RPIA ribose 5-phosphate isomerase A -3.38539
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -3.35265
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -3.34788
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -3.26972
GLT8D1 glycosyltransferase 8 domain containing 1 -3.26597
PARP1 poly (ADP-ribose) polymerase 1 -3.26523
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -3.21223
UBE3C ubiquitin protein ligase E3C -3.2038
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -3.20374
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.19549
ZDHHC6 zinc finger, DHHC-type containing 6 -3.19356
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 -3.19253
MIS18A MIS18 kinetochore protein A -3.17153
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -3.1614
SHMT1 serine hydroxymethyltransferase 1 (soluble) -3.15055
STIMATE STIM activating enhancer -3.14956
LAGE3 L antigen family, member 3 -3.14401
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -3.13939
RFC5 replication factor C (activator 1) 5, 36.5kDa -3.1354
CETN2 centrin, EF-hand protein, 2 -3.06351
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.02981
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -3.02867
VDAC1 voltage-dependent anion channel 1 -3.02036
ARFIP2 ADP-ribosylation factor interacting protein 2 -3.02015
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -3.01083
NUCB2 nucleobindin 2 -3.00232
TK1 thymidine kinase 1, soluble -2.99176
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.98046
LOC124907782 dual specificity protein phosphatase 22 -2.9668
PRUNE1 prune exopolyphosphatase 1 -2.9192
HADH hydroxyacyl-CoA dehydrogenase -2.91593
ECH1 enoyl CoA hydratase 1, peroxisomal -2.9021
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -2.89675
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.89189
TFDP1 transcription factor Dp-1 -2.88924
MRPS2 mitochondrial ribosomal protein S2 -2.88238
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -2.87375
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -2.87155
TSEN2 TSEN2 tRNA splicing endonuclease subunit -2.866
NLRP2B NLR family pyrin domain containing 2B -2.85447
DHFR dihydrofolate reductase -2.84127
TMEM97 transmembrane protein 97 -2.82731
RBM15B RNA binding motif protein 15B -2.8196
PPIC peptidylprolyl isomerase C (cyclophilin C) -2.80474
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A -2.79893
FBXL12 F-box and leucine-rich repeat protein 12 -2.79586
PAGR1 PAXIP1 associated glutamate-rich protein 1 -2.79134
TBC1D10C TBC1 domain family, member 10C -2.78393
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 -2.77607
HMGN3 high mobility group nucleosomal binding domain 3 -2.7736
NCAPG2 non-SMC condensin II complex, subunit G2 -2.77029
HSPA1A heat shock 70kDa protein 1A -2.7697
ARF5 ADP-ribosylation factor 5 -2.75068
PGRMC1 progesterone receptor membrane component 1 -2.74467
CCNB2 cyclin B2 -2.72346
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 -2.72325
HTD2 hydroxyacyl-thioester dehydratase type 2 -2.70372
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -2.70294
TRIP13 thyroid hormone receptor interactor 13 -2.6625
UNC119B unc-119 homolog B (C. elegans) -2.64882
FANCI Fanconi anemia, complementation group I -2.64394
HMOX1 heme oxygenase 1 -2.63326
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -2.63114
LZTFL1 leucine zipper transcription factor-like 1 -2.60533
ATP5IF1 ATP synthase inhibitory factor subunit 1 -2.60037
FEN1 flap structure-specific endonuclease 1 -2.5877
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -2.58336
KIF15 kinesin family member 15 -2.58189
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -2.58124
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -2.56181
IFT81 intraflagellar transport 81 -2.55444
PXMP2 peroxisomal membrane protein 2, 22kDa -2.5347
MAPK9 mitogen-activated protein kinase 9 -2.51903
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -2.51399
INTS3 integrator complex subunit 3 -2.5137
NENF neudesin neurotrophic factor -2.50288
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.48791
RUVBL1 RuvB-like AAA ATPase 1 -2.47972
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -2.4793
KLHDC2 kelch domain containing 2 -2.46267
TOR3A torsin family 3, member A -2.46014
MLEC malectin -2.45858
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.45413
ZNF83 zinc finger protein 83 -2.44997
MYH10 myosin, heavy chain 10, non-muscle -2.44963
NEK4 NIMA-related kinase 4 -2.44823
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -2.43762
CDK2 cyclin-dependent kinase 2 -2.42775
PEX11A peroxisomal biogenesis factor 11 alpha -2.42375
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -2.42231
ADI1 acireductone dioxygenase 1 -2.42112
MRPL11 mitochondrial ribosomal protein L11 -2.41844
MSH6 mutS homolog 6 -2.40366
TMCO1 transmembrane and coiled-coil domains 1 -2.40186
MSTO1 misato 1, mitochondrial distribution and morphology regulator -2.39787
TM9SF3 transmembrane 9 superfamily member 3 -2.38689
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.37367
TEDC2 tubulin epsilon and delta complex 2 -2.36763
PARN poly(A)-specific ribonuclease -2.34861
BCL7C B-cell CLL/lymphoma 7C -2.3453
CASP3 caspase 3, apoptosis-related cysteine peptidase -2.33978
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.33868
CCDC47 coiled-coil domain containing 47 -2.33524
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.3292
MYCBP MYC binding protein -2.32841
RPA3 replication protein A3, 14kDa -2.32673
HIRA histone cell cycle regulator -2.32602
HMGN2 high mobility group nucleosomal binding domain 2 -2.32312
PYCR3 pyrroline-5-carboxylate reductase 3 -2.32166
CDC6 cell division cycle 6 -2.32131
MRPS7 mitochondrial ribosomal protein S7 -2.31915
SLC2A4RG SLC2A4 regulator -2.31875
MRPL39 mitochondrial ribosomal protein L39 -2.31251
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 -2.31007
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor -2.30981
QTRT1 queuine tRNA-ribosyltransferase 1 -2.29782
KIF11 kinesin family member 11 -2.29289
ELP5 elongator acetyltransferase complex subunit 5 -2.29278
MRPL16 mitochondrial ribosomal protein L16 -2.28682
GAMT guanidinoacetate N-methyltransferase -2.28626
CPA2 carboxypeptidase A2 (pancreatic) -2.27927
NUP62 nucleoporin 62kDa -2.27582
PDF peptide deformylase (mitochondrial) -2.27481
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -2.27359
ZNF273 zinc finger protein 273 -2.27093
POLR2J3 polymerase (RNA) II (DNA directed) polypeptide J3 -2.26775
KIF14 kinesin family member 14 -2.26649
NELFCD negative elongation factor complex member C/D -2.25739
KIFC1 kinesin family member C1 -2.25727
CADM1 cell adhesion molecule 1 -2.25477
CENPS-CORT CENPS-CORT readthrough -2.25464
UBE3B ubiquitin protein ligase E3B -2.23845
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.23142
PLK1 polo-like kinase 1 -2.22716
FZD7 frizzled class receptor 7 -2.22327
FAM174B family with sequence similarity 174, member B -2.22263
PDIA5 protein disulfide isomerase family A, member 5 -2.21777
TRIM52 tripartite motif containing 52 -2.21423
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.20203
PRCP prolylcarboxypeptidase (angiotensinase C) -2.2002
TRMT5 tRNA methyltransferase 5 -2.19442
CDC40 cell division cycle 40 -2.18804
C2CD5 C2 calcium-dependent domain containing 5 -2.18461
COPS7A COP9 signalosome subunit 7A -2.17216
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.17028
RMI1 RecQ mediated genome instability 1 -2.16985
TATDN2 TatD DNase domain containing 2 -2.15385
CFAP20 cilia and flagella associated protein 20 -2.14477
COG4 component of oligomeric golgi complex 4 -2.14008
TMEM183A transmembrane protein 183A -2.13835
UBE2A ubiquitin-conjugating enzyme E2A -2.13719
TMEM243 transmembrane protein 243, mitochondrial -2.13438
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.13053
SPPL2A signal peptide peptidase like 2A -2.13006
MSH2 mutS homolog 2 -2.12205
FANCG Fanconi anemia, complementation group G -2.12194
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) -2.12121
KANSL1 KAT8 regulatory NSL complex subunit 1 -2.11521
CDK5 cyclin-dependent kinase 5 -2.11295
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -2.10751
POLI polymerase (DNA directed) iota -2.1057
RXYLT1 ribitol xylosyltransferase 1 -2.10264
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -2.10163
ECM2 extracellular matrix protein 2, female organ and adipocyte specific -2.09842
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -2.07465
TP53RK TP53 regulating kinase -2.07313
UBE2G2 ubiquitin-conjugating enzyme E2G 2 -2.07038
CIRBP cold inducible RNA binding protein -2.06478
MOCS2 molybdenum cofactor synthesis 2 -2.05662
RRM2 ribonucleotide reductase M2 -2.05459
GID8 GID complex subunit 8 -2.04387
PIGN phosphatidylinositol glycan anchor biosynthesis, class N -2.03997
PROS1 protein S (alpha) -2.03915
IFT52 intraflagellar transport 52 -2.03511
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -2.02714
MCM10 minichromosome maintenance complex component 10 -2.02321
CD99 CD99 molecule -2.02206
RPL26L1 ribosomal protein L26-like 1 -2.01979
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.01866
DUT deoxyuridine triphosphatase -2.0186
ANKRD10 ankyrin repeat domain 10 -2.0173
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -2.00958
ABT1 activator of basal transcription 1 -2.00902
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -2.00542
PTTG1 pituitary tumor-transforming 1 -2.0017