CRCGN012_HEPG2_24H:G19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description endosulfan 40.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

1060 genes differentially expressed following the CRCGN012_HEPG2_24H:G19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 10.0
TIMP2 TIMP metallopeptidase inhibitor 2 8.60492
KIFBP kinesin family binding protein 8.14186
TRIB3 tribbles pseudokinase 3 8.11709
TXNRD1 thioredoxin reductase 1 7.95722
IGFBP3 insulin-like growth factor binding protein 3 7.32177
LCN2 lipocalin 2 7.22767
MYC v-myc avian myelocytomatosis viral oncogene homolog 7.21228
INPP1 inositol polyphosphate-1-phosphatase 7.17628
CIAO3 cytosolic iron-sulfur assembly component 3 7.04246
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 7.03243
FOSL1 FOS-like antigen 1 6.9773
STX1A syntaxin 1A (brain) 6.9679
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 6.92326
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 6.78646
LRP10 low density lipoprotein receptor-related protein 10 6.78202
SQOR sulfide quinone oxidoreductase 6.59055
MICALL1 MICAL-like 1 6.57266
EGR1 early growth response 1 6.47523
MVP major vault protein 6.28464
GFPT1 glutamine--fructose-6-phosphate transaminase 1 6.22481
IER3 immediate early response 3 6.10341
GFOD1 glucose-fructose oxidoreductase domain containing 1 6.08727
CASC3 cancer susceptibility candidate 3 6.06806
SQSTM1 sequestosome 1 6.04269
DDIT4 DNA-damage-inducible transcript 4 5.91076
PTPN12 protein tyrosine phosphatase, non-receptor type 12 5.58041
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 5.54055
PRAF2 PRA1 domain family, member 2 5.48402
ACOT9 acyl-CoA thioesterase 9 5.35994
CNPY3 canopy FGF signaling regulator 3 5.3465
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 5.21768
IL4R interleukin 4 receptor 5.1622
TRIB1 tribbles pseudokinase 1 5.05972
UBQLN2 ubiquilin 2 4.99683
ATP11B ATPase, class VI, type 11B 4.90532
KCNK1 potassium channel, two pore domain subfamily K, member 1 4.8536
TOMM34 translocase of outer mitochondrial membrane 34 4.79785
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 4.74135
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 4.68586
MNAT1 MNAT CDK-activating kinase assembly factor 1 4.59806
KLHL21 kelch-like family member 21 4.56441
CYCS cytochrome c, somatic 4.5455
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 4.49428
NUP58 nucleoporin 58 4.46152
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 4.43375
TERF2IP telomeric repeat binding factor 2, interacting protein 4.38934
CAB39 calcium binding protein 39 4.3665
SOX4 SRY (sex determining region Y)-box 4 4.33246
GPATCH8 G patch domain containing 8 4.30523
ZMYM2 zinc finger, MYM-type 2 4.29518
H2BC21 H2B clustered histone 21 4.29416
SHB Src homology 2 domain containing adaptor protein B 4.28883
CSNK1E casein kinase 1, epsilon 4.21793
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 4.21376
RALB v-ral simian leukemia viral oncogene homolog B 4.19291
NR1H2 nuclear receptor subfamily 1, group H, member 2 4.17189
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 4.15838
RAB11FIP2 RAB11 family interacting protein 2 (class I) 4.12959
GOLT1B golgi transport 1B 4.08152
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 4.06218
PHKA1 phosphorylase kinase, alpha 1 (muscle) 4.05959
MBNL1 muscleblind-like splicing regulator 1 4.05582
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 4.05259
BIRC2 baculoviral IAP repeat containing 2 4.04535
UBXN7 UBX domain protein 7 4.04213
AARS1 alanyl-tRNA synthetase 1 3.98752
CDK7 cyclin-dependent kinase 7 3.94993
ZNF410 zinc finger protein 410 3.91473
KDM5A lysine (K)-specific demethylase 5A 3.88796
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 3.88465
OSGIN2 oxidative stress induced growth inhibitor family member 2 3.88186
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 3.86416
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.8612
TICAM1 toll-like receptor adaptor molecule 1 3.84259
VAT1 vesicle amine transport 1 3.82727
CAMTA2 calmodulin binding transcription activator 2 3.82566
ABHD4 abhydrolase domain containing 4 3.82087
ANO1 anoctamin 1, calcium activated chloride channel 3.81863
TRIM13 tripartite motif containing 13 3.80454
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 3.8019
TES testin LIM domain protein 3.79941
ADGRG1 adhesion G protein-coupled receptor G1 3.73731
ANKRD11 ankyrin repeat domain 11 3.73119
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 3.72474
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.71999
LOC128125814 uncharacterized LOC128125814 3.69248
PNKP polynucleotide kinase 3'-phosphatase 3.68276
ATOSB atos homolog B 3.67726
SOCS2 suppressor of cytokine signaling 2 3.67472
GARS1 glycyl-tRNA synthetase 1 3.65541
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 3.63803
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 3.60591
SMAD3 SMAD family member 3 3.58512
PCDHB11 protocadherin beta 11 3.5607
ZFP36 ZFP36 ring finger protein 3.5453
MTFR1 mitochondrial fission regulator 1 3.51613
PPARD peroxisome proliferator-activated receptor delta 3.45124
MYH9 myosin, heavy chain 9, non-muscle 3.44837
PLK3 polo-like kinase 3 3.44628
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 3.40002
SARS1 seryl-tRNA synthetase 1 3.37028
ZFAND1 zinc finger, AN1-type domain 1 3.3492
CLIP4 CAP-GLY domain containing linker protein family, member 4 3.32975
TRAPPC14 trafficking protein particle complex subunit 14 3.30584
DHRS7 dehydrogenase/reductase (SDR family) member 7 3.30312
SH3GLB1 SH3-domain GRB2-like endophilin B1 3.29815
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 3.2699
SMNDC1 survival motor neuron domain containing 1 3.2603
BUD31 BUD31 homolog (S. cerevisiae) 3.24541
GDI1 GDP dissociation inhibitor 1 3.22257
BGN biglycan 3.21208
KRT86 keratin 86, type II 3.19931
GRB10 growth factor receptor-bound protein 10 3.19658
GIPC1 GIPC PDZ domain containing family, member 1 3.19337
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 3.1843
DNM1L dynamin 1-like 3.17971
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 3.16905
ASCC1 activating signal cointegrator 1 complex subunit 1 3.1524
IFRD1 interferon-related developmental regulator 1 3.14708
HDAC7 histone deacetylase 7 3.14255
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 3.13678
TMEM184B transmembrane protein 184B 3.10938
ZYX zyxin 3.09097
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 3.08453
P2RY10 purinergic receptor P2Y, G-protein coupled, 10 3.07313
UNC13A unc-13 homolog A (C. elegans) 3.06683
RUSC2 RUN and SH3 domain containing 2 3.05781
EAPP E2F-associated phosphoprotein 3.05528
ZNF195 zinc finger protein 195 3.04825
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 3.04299
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 3.02902
HTRA1 HtrA serine peptidase 1 3.02447
NPC1 Niemann-Pick disease, type C1 3.0164
SEC14L1 SEC14-like 1 (S. cerevisiae) 3.0076
PRR15L proline rich 15-like 3.00698
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 3.00622
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 3.00496
GPC1 glypican 1 3.00252
PTPN14 protein tyrosine phosphatase, non-receptor type 14 3.00117
STX5 syntaxin 5 2.98778
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.98089
EPN2 epsin 2 2.97701
YARS1 tyrosyl-tRNA synthetase 1 2.97315
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) 2.97099
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.96646
GREM1 gremlin 1, DAN family BMP antagonist 2.9629
GTPBP2 GTP binding protein 2 2.9595
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2.95916
EGFR epidermal growth factor receptor 2.94967
TESK1 testis-specific kinase 1 2.94806
MEST mesoderm specific transcript 2.9405
NIBAN1 niban apoptosis regulator 1 2.93745
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.93075
FOXJ3 forkhead box J3 2.92224
PSPC1 paraspeckle component 1 2.91524
TP53BP2 tumor protein p53 binding protein 2 2.91279
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 2.91147
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 2.91062
KDM6B lysine (K)-specific demethylase 6B 2.90926
EPHA2 EPH receptor A2 2.90869
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 2.90421
LIN37 lin-37 DREAM MuvB core complex component 2.90259
LARP6 La ribonucleoprotein domain family, member 6 2.89966
MSN moesin 2.89772
ALAS1 5'-aminolevulinate synthase 1 2.87847
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.86344
RHOG ras homolog family member G 2.86279
JOSD1 Josephin domain containing 1 2.86172
MEAK7 MTOR associated protein, eak-7 homolog 2.85345
MON1B MON1 secretory trafficking family member B 2.8524
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.84299
TM6SF1 transmembrane 6 superfamily member 1 2.84238
CFLAR CASP8 and FADD-like apoptosis regulator 2.84163
PRKCD protein kinase C, delta 2.83988
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 2.83155
SNW1 SNW domain containing 1 2.83149
DOHH deoxyhypusine hydroxylase/monooxygenase 2.81628
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.81368
DCP1A decapping mRNA 1A 2.81349
CCPG1 cell cycle progression 1 2.7989
ATF6 activating transcription factor 6 2.79327
CD9 CD9 molecule 2.79226
FASTKD5 FAST kinase domains 5 2.78718
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 2.78471
YIPF3 Yip1 domain family, member 3 2.78423
MTERF3 mitochondrial transcription termination factor 3 2.77898
IPO13 importin 13 2.76892
KLF7 Kruppel-like factor 7 (ubiquitous) 2.76286
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 2.75428
PPARG peroxisome proliferator-activated receptor gamma 2.75259
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 2.75158
CARS1 cysteinyl-tRNA synthetase 1 2.74719
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 2.74385
PRKCQ protein kinase C, theta 2.73556
MAP7D1 MAP7 domain containing 1 2.73493
SPINT1 serine peptidase inhibitor, Kunitz type 1 2.72939
CSNK1G3 casein kinase 1, gamma 3 2.72429
NPDC1 neural proliferation, differentiation and control, 1 2.72135
CHUK conserved helix-loop-helix ubiquitous kinase 2.71973
PTPRF protein tyrosine phosphatase, receptor type, F 2.716
LSG1 large 60S subunit nuclear export GTPase 1 2.70893
GHITM growth hormone inducible transmembrane protein 2.70031
FNDC3B fibronectin type III domain containing 3B 2.69699
GFI1 growth factor independent 1 transcription repressor 2.6884
WBP4 WW domain binding protein 4 2.68729
ZNF358 zinc finger protein 358 2.6802
SPAG7 sperm associated antigen 7 2.67482
KLHL36 kelch-like family member 36 2.67209
HABP4 hyaluronan binding protein 4 2.66722
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.66491
ZC3H15 zinc finger CCCH-type containing 15 2.66475
DUSP6 dual specificity phosphatase 6 2.66378
NCK2 NCK adaptor protein 2 2.66233
LIF leukemia inhibitory factor 2.65899
STN1 STN1 subunit of CST complex 2.65421
EXOC6B exocyst complex component 6B 2.65354
ITGB5 integrin, beta 5 2.65151
TCP11L1 t-complex 11, testis-specific-like 1 2.64998
AHDC1 AT hook, DNA binding motif, containing 1 2.64846
FHL2 four and a half LIM domains 2 2.64546
NARS1 asparaginyl-tRNA synthetase 1 2.64112
DUSP3 dual specificity phosphatase 3 2.6398
SPAG9 sperm associated antigen 9 2.63501
PPP1R13L protein phosphatase 1, regulatory subunit 13 like 2.63324
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 2.62902
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa 2.62531
SECISBP2L SECIS binding protein 2-like 2.60926
MBTD1 mbt domain containing 1 2.60723
MOK MOK protein kinase 2.601
SYNJ2 synaptojanin 2 2.59189
ITCH itchy E3 ubiquitin protein ligase 2.59021
NRBF2 nuclear receptor binding factor 2 2.58907
C2CD2L C2CD2-like 2.5836
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent 2.58025
EN1 engrailed homeobox 1 2.57475
ETV6 ets variant 6 2.57284
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.57199
CCSER2 coiled-coil serine-rich protein 2 2.57184
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 2.56658
UBE2W ubiquitin-conjugating enzyme E2W (putative) 2.56629
UPP1 uridine phosphorylase 1 2.56284
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 2.56001
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 2.55812
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 2.55608
EPN3 epsin 3 2.55474
NT5E 5'-nucleotidase, ecto (CD73) 2.54509
ZNF343 zinc finger protein 343 2.53932
GRAMD2B GRAM domain containing 2B 2.53865
ATF4 activating transcription factor 4 2.53857
MACF1 microtubule-actin crosslinking factor 1 2.53812
PUM3 pumilio RNA binding family member 3 2.52837
KLHL24 kelch-like family member 24 2.52764
ARL8B ADP-ribosylation factor-like 8B 2.52761
PEX26 peroxisomal biogenesis factor 26 2.52654
PDGFA platelet-derived growth factor alpha polypeptide 2.52594
RTCA RNA 3'-terminal phosphate cyclase 2.52071
DOCK10 dedicator of cytokinesis 10 2.50801
SYNGR3 synaptogyrin 3 2.50254
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) 2.50021
MEF2D myocyte enhancer factor 2D 2.49709
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 2.49477
ACTN4 actinin, alpha 4 2.49244
NANOS3 nanos homolog 3 (Drosophila) 2.49145
MAP1S microtubule-associated protein 1S 2.48795
ZNF23 zinc finger protein 23 2.48729
ADRA2C adrenoceptor alpha 2C 2.48306
YIPF4 Yip1 domain family, member 4 2.48209
SUMF2 sulfatase modifying factor 2 2.47713
TLN1 talin 1 2.47623
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 2.47504
RB1CC1 RB1-inducible coiled-coil 1 2.47465
PHF20L1 PHD finger protein 20-like 1 2.46987
PRTN3 proteinase 3 2.4691
TARS1 threonyl-tRNA synthetase 1 2.46753
BPGM 2,3-bisphosphoglycerate mutase 2.46098
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 2.45219
IARS1 isoleucyl-tRNA synthetase 1 2.45101
H2BC6 H2B clustered histone 6 2.44884
THAP1 THAP domain containing, apoptosis associated protein 1 2.44673
TGFB1I1 transforming growth factor beta 1 induced transcript 1 2.44175
TRPM6 transient receptor potential cation channel, subfamily M, member 6 2.44119
CMKLR2 chemerin chemokine-like receptor 2 2.43851
ITGA10 integrin, alpha 10 2.43316
RBM15B RNA binding motif protein 15B 2.43272
KIF26B kinesin family member 26B 2.43048
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.42642
BCL10 B-cell CLL/lymphoma 10 2.4253
CNIH4 cornichon family AMPA receptor auxiliary protein 4 2.42316
ADAM9 ADAM metallopeptidase domain 9 2.41493
MED15 mediator complex subunit 15 2.41483
ATXN3 ataxin 3 2.41477
FABP2 fatty acid binding protein 2, intestinal 2.41105
INHBA inhibin, beta A 2.40703
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 2.40693
QPCTL glutaminyl-peptide cyclotransferase-like 2.40559
TEX10 testis expressed 10 2.40512
STEEP1 STING1 ER exit protein 1 2.4027
EHD2 EH-domain containing 2 2.40153
PCNX1 pecanex 1 2.40058
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 2.39585
DRD1 dopamine receptor D1 2.39452
RNMT RNA (guanine-7-) methyltransferase 2.39384
UNC5B unc-5 homolog B (C. elegans) 2.3921
BCAT1 branched chain amino-acid transaminase 1, cytosolic 2.38689
BMAL2 basic helix-loop-helix ARNT like 2 2.38621
RFK riboflavin kinase 2.38554
BECN1 beclin 1, autophagy related 2.3824
RSF1 remodeling and spacing factor 1 2.38108
PTX3 pentraxin 3, long 2.3807
POMZP3 POM121 and ZP3 fusion 2.3792
IL5 interleukin 5 2.37864
IL2 interleukin 2 2.37366
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 2.37319
PCDH1 protocadherin 1 2.37115
LPGAT1 lysophosphatidylglycerol acyltransferase 1 2.36982
PXDC1 PX domain containing 1 2.36978
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 2.35862
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.35763
ANKRD40 ankyrin repeat domain 40 2.3566
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12 2.35613
TGFB2 transforming growth factor, beta 2 2.34809
LOC127933115 uncharacterized LOC127933115 2.34659
KRT23 keratin 23, type I 2.34453
LCOR ligand dependent nuclear receptor corepressor 2.34431
SMAD2 SMAD family member 2 2.34286
BCL2L13 BCL2-like 13 (apoptosis facilitator) 2.34281
YAF2 YY1 associated factor 2 2.34073
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 2.34036
NCF2 neutrophil cytosolic factor 2 2.33908
KAT6A K(lysine) acetyltransferase 6A 2.33904
CLDN4 claudin 4 2.3386
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 2.33711
CSRNP2 cysteine-serine-rich nuclear protein 2 2.33168
WDR13 WD repeat domain 13 2.3313
MED8 mediator complex subunit 8 2.32872
KLF13 Kruppel-like factor 13 2.32686
CST7 cystatin F (leukocystatin) 2.32662
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 2.32438
ZNF12 zinc finger protein 12 2.32012
DUSP8 dual specificity phosphatase 8 2.32009
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 2.31979
MYO6 myosin VI 2.31956
CDC37L1 cell division cycle 37-like 1 2.31709
IL7R interleukin 7 receptor 2.31586
ANKRD44 ankyrin repeat domain 44 2.31547
AFAP1 actin filament associated protein 1 2.31398
ARHGAP22 Rho GTPase activating protein 22 2.31268
ZBTB35 zinc finger and BTB domain containing 35 2.3095
IL10 interleukin 10 2.30658
PPP1R13B protein phosphatase 1, regulatory subunit 13B 2.30314
MMUT methylmalonyl-CoA mutase 2.30128
ST18 suppression of tumorigenicity 18, zinc finger 2.30112
ANXA1 annexin A1 2.29965
ITGA8 integrin, alpha 8 2.29825
RNF220 ring finger protein 220 2.29763
ULK1 unc-51 like autophagy activating kinase 1 2.29468
CTNND1 catenin (cadherin-associated protein), delta 1 2.29279
GNL1 guanine nucleotide binding protein-like 1 2.29244
ZMYM5 zinc finger, MYM-type 5 2.28901
KYAT3 kynurenine aminotransferase 3 2.28701
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 2.28672
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 2.28404
CYTH2 cytohesin 2 2.28168
H2BC17 H2B clustered histone 17 2.27154
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 2.27028
SCNN1B sodium channel, non voltage gated 1 beta subunit 2.26551
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 2.26477
SF3A2 splicing factor 3a, subunit 2, 66kDa 2.25899
GBE1 glucan (1,4-alpha-), branching enzyme 1 2.25816
PVR poliovirus receptor 2.25704
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas) 2.25656
PLAUR plasminogen activator, urokinase receptor 2.25525
SYF2 SYF2 pre-mRNA-splicing factor 2.25416
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) 2.25131
HPSE heparanase 2.25127
KCMF1 potassium channel modulatory factor 1 2.25046
DMTF1 cyclin D binding myb-like transcription factor 1 2.25039
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 2.24866
KRT7 keratin 7, type II 2.24815
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 2.24809
CHD1 chromodomain helicase DNA binding protein 1 2.24722
MMP1 matrix metallopeptidase 1 2.24664
EMP1 epithelial membrane protein 1 2.23839
IRAK4 interleukin-1 receptor-associated kinase 4 2.2339
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 2.23094
RWDD1 RWD domain containing 1 2.23084
KCNK2 potassium channel, two pore domain subfamily K, member 2 2.22973
GADD45A growth arrest and DNA-damage-inducible, alpha 2.22787
PADI2 peptidyl arginine deiminase, type II 2.22747
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2 2.22694
MCPH1 microcephalin 1 2.21911
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 2.21868
TFCP2L1 transcription factor CP2-like 1 2.21714
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 2.21692
RRAGA Ras-related GTP binding A 2.21622
FEZF2 FEZ family zinc finger 2 2.21517
PARVB parvin, beta 2.21497
AIRIM AFG2 interacting ribosome maturation factor 2.21468
RNF113A ring finger protein 113A 2.21407
NCALD neurocalcin delta 2.21397
EIF4A2 eukaryotic translation initiation factor 4A2 2.21335
LRRC8B leucine rich repeat containing 8 family, member B 2.21201
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 2.21194
MGLL monoglyceride lipase 2.20819
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 2.20549
ASNS asparagine synthetase (glutamine-hydrolyzing) 2.2053
SBSPON somatomedin B and thrombospondin, type 1 domain containing 2.20402
ZNF430 zinc finger protein 430 2.20092
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 2.19874
SMIM44 small integral membrane protein 44 2.19862
RBMX2 RNA binding motif protein, X-linked 2 2.19374
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria 2.19278
SPNS1 spinster homolog 1 (Drosophila) 2.19176
USP3 ubiquitin specific peptidase 3 2.18115
TM4SF1 transmembrane 4 L six family member 1 2.18075
EIF3A eukaryotic translation initiation factor 3, subunit A 2.17834
YY1AP1 YY1 associated protein 1 2.17757
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 2.17753
LIM2 lens intrinsic membrane protein 2, 19kDa 2.17578
DENND4C DENN/MADD domain containing 4C 2.17519
MAPK12 mitogen-activated protein kinase 12 2.17508
ETHE1 ethylmalonic encephalopathy 1 2.17155
SPRYD7 SPRY domain containing 7 2.17002
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 2.16869
SLC35F2 solute carrier family 35, member F2 2.16573
ARL5A ADP-ribosylation factor-like 5A 2.16518
EIF3D eukaryotic translation initiation factor 3, subunit D 2.16287
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 2.16243
TSTD2 thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 2.16123
LAMC2 laminin, gamma 2 2.16058
DGKA diacylglycerol kinase, alpha 80kDa 2.16051
IFNAR1 interferon (alpha, beta and omega) receptor 1 2.15922
MARS1 methionyl-tRNA synthetase 1 2.15921
RGS10 regulator of G-protein signaling 10 2.15917
CHMP5 charged multivesicular body protein 5 2.15495
PSORS1C2 psoriasis susceptibility 1 candidate 2 2.1545
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 2.15434
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2.15394
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) 2.1521
ARL14 ADP-ribosylation factor-like 14 2.15078
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 2.15048
ZMIZ1 zinc finger, MIZ-type containing 1 2.15015
ARID4B AT rich interactive domain 4B (RBP1-like) 2.1486
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 2.14744
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 2.14566
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 2.14389
ELAVL3 ELAV like neuron-specific RNA binding protein 3 2.14355
MARCHF5 membrane associated ring-CH-type finger 5 2.14165
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 2.13984
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 2.13921
ANXA11 annexin A11 2.13899
DDRGK1 DDRGK domain containing 1 2.13893
SP100 SP100 nuclear antigen 2.13837
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 2.13826
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 2.13723
MAGIX MAGI family member, X-linked 2.13582
CORO1A coronin, actin binding protein, 1A 2.13493
AGO2 argonaute RISC catalytic component 2 2.13362
MEAF6 MYST/Esa1-associated factor 6 2.13247
TMEM156 transmembrane protein 156 2.13219
PARP6 poly (ADP-ribose) polymerase family, member 6 2.13132
TRIM3 tripartite motif containing 3 2.1304
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 2.12932
RASAL2 RAS protein activator like 2 2.1282
FGF12 fibroblast growth factor 12 2.1271
PKN1 protein kinase N1 2.12448
STAT5A signal transducer and activator of transcription 5A 2.12351
IL37 interleukin 37 2.12289
JUN jun proto-oncogene 2.11906
ARHGAP10 Rho GTPase activating protein 10 2.11893
KCTD9 potassium channel tetramerization domain containing 9 2.11868
SUN2 Sad1 and UNC84 domain containing 2 2.11678
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 2.11652
MRPS18B mitochondrial ribosomal protein S18B 2.1155
SPAG1 sperm associated antigen 1 2.11377
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 2.11245
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.11004
CEP170 centrosomal protein 170kDa 2.10983
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2 2.10907
AZIN2 antizyme inhibitor 2 2.10885
IL18R1 interleukin 18 receptor 1 2.10723
CCNJ cyclin J 2.10535
KRT81 keratin 81, type II 2.10307
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 2.10236
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase 2.1018
TMEM204 transmembrane protein 204 2.10033
GABARAPL1 GABA(A) receptor-associated protein like 1 2.0992
ERCC6 excision repair cross-complementation group 6 2.09859
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 2.09759
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 2.09717
RMC1 regulator of MON1-CCZ1 2.09526
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma 2.09347
TEAD3 TEA domain family member 3 2.08651
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 2.08637
H3-4 H3.4 histone, cluster member 2.0853
BAMBI BMP and activin membrane-bound inhibitor 2.08334
SNX13 sorting nexin 13 2.08299
SFXN3 sideroflexin 3 2.07844
MKRN1 makorin ring finger protein 1 2.07597
CERS6 ceramide synthase 6 2.07575
COQ10B coenzyme Q10 homolog B (S. cerevisiae) 2.07537
RAB14 RAB14, member RAS oncogene family 2.0747
VAC14 Vac14 homolog (S. cerevisiae) 2.07464
KLF9 Kruppel-like factor 9 2.07407
UFC1 ubiquitin-fold modifier conjugating enzyme 1 2.07393
POGK pogo transposable element with KRAB domain 2.07384
MMP7 matrix metallopeptidase 7 2.07261
BAZ1B bromodomain adjacent to zinc finger domain, 1B 2.07079
ITPKC inositol-trisphosphate 3-kinase C 2.06697
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 2.06697
STRN4 striatin, calmodulin binding protein 4 2.06693
PLA2R1 phospholipase A2 receptor 1, 180kDa 2.06524
MSI1 musashi RNA-binding protein 1 2.06496
ATP13A3 ATPase type 13A3 2.06214
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 2.06212
STIM1 stromal interaction molecule 1 2.06198
PDGFB platelet-derived growth factor beta polypeptide 2.059
CLCF1 cardiotrophin-like cytokine factor 1 2.05454
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 2.05449
ARID5B AT rich interactive domain 5B (MRF1-like) 2.05421
BICRAL BICRA like chromatin remodeling complex associated protein 2.05312
GPATCH2L G patch domain containing 2-like 2.05291
BICRA BRD4 interacting chromatin remodeling complex associated protein 2.05171
SERINC1 serine incorporator 1 2.05159
PCGF1 polycomb group ring finger 1 2.05157
ZNHIT6 zinc finger, HIT-type containing 6 2.05145
PRPF3 pre-mRNA processing factor 3 2.05035
IL2RA interleukin 2 receptor, alpha 2.05004
CDK8 cyclin-dependent kinase 8 2.04993
IER2 immediate early response 2 2.0494
GOLT1A golgi transport 1A 2.04878
EPYC epiphycan 2.04772
PDCD1LG2 programmed cell death 1 ligand 2 2.04726
NTAQ1 N-terminal glutamine amidase 1 2.0471
XPOT exportin, tRNA 2.04597
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 2.04571
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13 2.04413
SUSD4 sushi domain containing 4 2.04074
CORO2B coronin, actin binding protein, 2B 2.04
TFE3 transcription factor binding to IGHM enhancer 3 2.03977
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit 2.03973
GOSR1 golgi SNAP receptor complex member 1 2.03915
OR7A10 olfactory receptor, family 7, subfamily A, member 10 2.03792
RBPJ recombination signal binding protein for immunoglobulin kappa J region 2.03641
LMO4 LIM domain only 4 2.0356
RGCC regulator of cell cycle 2.03369
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.03305
N4BP3 NEDD4 binding protein 3 2.0329
CREB5 cAMP responsive element binding protein 5 2.03181
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 2.02872
MCUR1 mitochondrial calcium uniporter regulator 1 2.0272
CAMK1D calcium/calmodulin-dependent protein kinase ID 2.02684
BLTP3B bridge-like lipid transfer protein family member 3B 2.02365
GRM3 glutamate receptor, metabotropic 3 2.02285
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 2.02284
UFM1 ubiquitin-fold modifier 1 2.02208
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.02133
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 2.02109
THBD thrombomodulin 2.01958
PTPRS protein tyrosine phosphatase, receptor type, S 2.0166
GABPB1 GA binding protein transcription factor, beta subunit 1 2.01524
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 2.01391
CALCOCO2 calcium binding and coiled-coil domain 2 2.01346
CRYGB crystallin, gamma B 2.01221
PURG purine-rich element binding protein G 2.00937
MRPL37 mitochondrial ribosomal protein L37 2.00758
EXO5 exonuclease 5 2.00632
FRMD4B FERM domain containing 4B 2.00607
ABHD5 abhydrolase domain containing 5 2.00138

decreased expression

Symbol Name Standardized Value
B4GAT1 beta-1,4-glucuronyltransferase 1 -10.0
TCTN1 tectonic family member 1 -9.78264
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -9.55791
CD320 CD320 molecule -8.87019
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -8.71361
MELK maternal embryonic leucine zipper kinase -8.35817
CCNB1 cyclin B1 -8.05291
PLK1 polo-like kinase 1 -8.008
CCDC86 coiled-coil domain containing 86 -7.57738
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -7.4231
PGAM4 phosphoglycerate mutase family member 4 -7.40416
NT5DC2 5'-nucleotidase domain containing 2 -7.33627
BLCAP bladder cancer associated protein -7.26577
PSRC1 proline/serine-rich coiled-coil 1 -7.09829
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -6.76291
PGM1 phosphoglucomutase 1 -6.73035
HSPB1 heat shock 27kDa protein 1 -6.71975
DERA deoxyribose-phosphate aldolase (putative) -6.71268
CCNA2 cyclin A2 -6.67328
ZW10 zw10 kinetochore protein -6.61052
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -6.39451
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -6.38794
CDK1 cyclin-dependent kinase 1 -6.35621
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -6.34651
LBR lamin B receptor -6.29093
TMEM109 transmembrane protein 109 -6.2273
ALDOC aldolase C, fructose-bisphosphate -6.21412
NUP85 nucleoporin 85kDa -6.20448
STMN1 stathmin 1 -6.09683
HMGA2 high mobility group AT-hook 2 -6.06381
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -6.04965
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -6.03247
AURKB aurora kinase B -6.00237
BIRC5 baculoviral IAP repeat containing 5 -5.9537
CDC20 cell division cycle 20 -5.92131
POLR1A polymerase (RNA) I polypeptide A, 194kDa -5.69501
ADI1 acireductone dioxygenase 1 -5.68322
TARBP1 TAR (HIV-1) RNA binding protein 1 -5.63966
SOAT2 sterol O-acyltransferase 2 -5.59015
TOP2A topoisomerase (DNA) II alpha 170kDa -5.5618
INTS3 integrator complex subunit 3 -5.56067
PCCB propionyl CoA carboxylase, beta polypeptide -5.48044
PARP1 poly (ADP-ribose) polymerase 1 -5.37568
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -5.36139
ANKRD10 ankyrin repeat domain 10 -5.25212
RUVBL1 RuvB-like AAA ATPase 1 -5.23002
GTF2A2 general transcription factor IIA, 2, 12kDa -5.21375
UBE2C ubiquitin-conjugating enzyme E2C -5.20347
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -5.16998
ASF1B anti-silencing function 1B histone chaperone -5.16714
CCNB2 cyclin B2 -5.14444
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -5.05206
ECH1 enoyl CoA hydratase 1, peroxisomal -5.0201
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -4.76619
PTTG1 pituitary tumor-transforming 1 -4.67015
COG7 component of oligomeric golgi complex 7 -4.58362
GAA glucosidase, alpha; acid -4.55383
HAT1 histone acetyltransferase 1 -4.48833
THAP11 THAP domain containing 11 -4.484
MLEC malectin -4.43577
UBE3C ubiquitin protein ligase E3C -4.38068
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -4.32309
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -4.30945
COG4 component of oligomeric golgi complex 4 -4.28471
MRPL12 mitochondrial ribosomal protein L12 -4.28106
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -4.24169
PAGR1 PAXIP1 associated glutamate-rich protein 1 -4.21501
CHEK2 checkpoint kinase 2 -4.17473
CDK4 cyclin-dependent kinase 4 -4.08313
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -4.07961
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -4.02771
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -4.02526
FBXL12 F-box and leucine-rich repeat protein 12 -3.9867
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -3.97621
PXMP2 peroxisomal membrane protein 2, 22kDa -3.95509
HADH hydroxyacyl-CoA dehydrogenase -3.94289
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.93015
CDCA3 cell division cycle associated 3 -3.85905
NUP62 nucleoporin 62kDa -3.85368
CBR1 carbonyl reductase 1 -3.84543
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -3.83337
TFDP1 transcription factor Dp-1 -3.80148
ISOC1 isochorismatase domain containing 1 -3.79548
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.7949
SCARB1 scavenger receptor class B, member 1 -3.79134
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -3.7684
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -3.75742
NIPSNAP1 nipsnap homolog 1 (C. elegans) -3.72618
CASP7 caspase 7, apoptosis-related cysteine peptidase -3.70189
ARFIP2 ADP-ribosylation factor interacting protein 2 -3.68102
NLRP2B NLR family pyrin domain containing 2B -3.64483
GAMT guanidinoacetate N-methyltransferase -3.62876
USP6NL USP6 N-terminal like -3.61357
KIF4A kinesin family member 4A -3.56982
TBC1D10C TBC1 domain family, member 10C -3.55143
FGFR4 fibroblast growth factor receptor 4 -3.55112
AKAP8 A kinase (PRKA) anchor protein 8 -3.54959
NCAPD2 non-SMC condensin I complex, subunit D2 -3.54556
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -3.52642
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -3.51177
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.50138
MRPS7 mitochondrial ribosomal protein S7 -3.50048
TRAP1 TNF receptor-associated protein 1 -3.49009
LDHD lactate dehydrogenase D -3.47084
CENPA centromere protein A -3.46843
FEN1 flap structure-specific endonuclease 1 -3.4649
NCAPG2 non-SMC condensin II complex, subunit G2 -3.45525
CENPX centromere protein X -3.45242
TEDC2 tubulin epsilon and delta complex 2 -3.41218
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -3.41032
CDKN3 cyclin-dependent kinase inhibitor 3 -3.40487
GALE UDP-galactose-4-epimerase -3.3994
MYCBP MYC binding protein -3.3853
RPA3 replication protein A3, 14kDa -3.36569
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -3.36411
NUP107 nucleoporin 107kDa -3.36365
SHMT1 serine hydroxymethyltransferase 1 (soluble) -3.36265
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.35426
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -3.35003
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -3.32633
TMEM97 transmembrane protein 97 -3.32577
EGF epidermal growth factor -3.32508
TWF2 twinfilin actin binding protein 2 -3.3206
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -3.31551
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -3.31332
FANCI Fanconi anemia, complementation group I -3.30411
NCAPH non-SMC condensin I complex, subunit H -3.28686
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -3.28154
ZWINT ZW10 interacting kinetochore protein -3.27424
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -3.26973
ICAM3 intercellular adhesion molecule 3 -3.26577
GPS1 G protein pathway suppressor 1 -3.25344
PRCP prolylcarboxypeptidase (angiotensinase C) -3.25159
COG2 component of oligomeric golgi complex 2 -3.24794
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -3.24648
TMEM14A transmembrane protein 14A -3.24028
PGRMC1 progesterone receptor membrane component 1 -3.23674
AMDHD2 amidohydrolase domain containing 2 -3.23367
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -3.20494
TK1 thymidine kinase 1, soluble -3.20077
PRUNE1 prune exopolyphosphatase 1 -3.18707
RPIA ribose 5-phosphate isomerase A -3.15107
DDB2 damage-specific DNA binding protein 2, 48kDa -3.13334
MGST2 microsomal glutathione S-transferase 2 -3.12294
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -3.10818
CPVL carboxypeptidase, vitellogenic-like -3.10742
RFC5 replication factor C (activator 1) 5, 36.5kDa -3.10536
UBE2S ubiquitin-conjugating enzyme E2S -3.07431
ALG6 ALG6, alpha-1,3-glucosyltransferase -3.07141
HNRNPM heterogeneous nuclear ribonucleoprotein M -3.0701
DNAAF5 dynein, axonemal, assembly factor 5 -3.06137
PIMREG PICALM interacting mitotic regulator -3.05804
GYG2 glycogenin 2 -3.04475
TRMT5 tRNA methyltransferase 5 -3.0398
ERBB2 erb-b2 receptor tyrosine kinase 2 -3.03947
HMMR hyaluronan-mediated motility receptor (RHAMM) -3.03671
IFT81 intraflagellar transport 81 -3.03521
PEPD peptidase D -3.03107
CCS copper chaperone for superoxide dismutase -3.02177
TRIP13 thyroid hormone receptor interactor 13 -2.99501
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -2.9934
HOOK2 hook microtubule-tethering protein 2 -2.97326
SRSF9 serine/arginine-rich splicing factor 9 -2.97279
QPRT quinolinate phosphoribosyltransferase -2.97111
RXYLT1 ribitol xylosyltransferase 1 -2.96574
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -2.96285
TRAPPC4 trafficking protein particle complex 4 -2.95268
GDF9 growth differentiation factor 9 -2.90745
DHFR dihydrofolate reductase -2.90221
NISCH nischarin -2.90204
CCND3 cyclin D3 -2.90158
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa -2.89724
CTSL cathepsin L -2.89375
CARHSP1 calcium regulated heat stable protein 1, 24kDa -2.88871
MCM10 minichromosome maintenance complex component 10 -2.88124
PDZK1 PDZ domain containing 1 -2.87697
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -2.87253
CDK2 cyclin-dependent kinase 2 -2.84965
H2AX H2A.X variant histone -2.84911
CD99 CD99 molecule -2.84292
LAGE3 L antigen family, member 3 -2.83862
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -2.83803
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -2.83802
WDR77 WD repeat domain 77 -2.836
COPS7A COP9 signalosome subunit 7A -2.82351
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.81398
MRPL16 mitochondrial ribosomal protein L16 -2.8084
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.79624
CDC37 cell division cycle 37 -2.79492
HDAC1 histone deacetylase 1 -2.79469
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.78946
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -2.78827
FOXM1 forkhead box M1 -2.77982
KHK ketohexokinase (fructokinase) -2.77698
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) -2.76687
CEP112 centrosomal protein 112kDa -2.76424
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.76367
ZNF318 zinc finger protein 318 -2.76281
SORD sorbitol dehydrogenase -2.75896
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.74622
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 -2.74517
EMC9 ER membrane protein complex subunit 9 -2.72865
KLHDC2 kelch domain containing 2 -2.71965
PBK PDZ binding kinase -2.71416
CEP43 centrosomal protein 43 -2.71171
PHKG2 phosphorylase kinase, gamma 2 (testis) -2.70684
RNASE7 ribonuclease, RNase A family, 7 -2.70475
LMNB1 lamin B1 -2.70437
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -2.70429
CDCA8 cell division cycle associated 8 -2.70043
PDIA5 protein disulfide isomerase family A, member 5 -2.6917
PROS1 protein S (alpha) -2.6913
SPAG5 sperm associated antigen 5 -2.68748
QTRT1 queuine tRNA-ribosyltransferase 1 -2.68591
DHRS1 dehydrogenase/reductase (SDR family) member 1 -2.67707
NCAPD3 non-SMC condensin II complex, subunit D3 -2.67649
KIF11 kinesin family member 11 -2.6734
TARBP2 TAR (HIV-1) RNA binding protein 2 -2.67112
CADPS2 Ca++-dependent secretion activator 2 -2.67037
GCDH glutaryl-CoA dehydrogenase -2.65923
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -2.65676
TROAP trophinin associated protein -2.65464
AAMP angio-associated, migratory cell protein -2.65462
AURKA aurora kinase A -2.64343
PEG10 paternally expressed 10 -2.63459
NRIP1 nuclear receptor interacting protein 1 -2.60748
KIF14 kinesin family member 14 -2.5991
BAX BCL2-associated X protein -2.59711
TNNC2 troponin C type 2 (fast) -2.57586
MIS18A MIS18 kinetochore protein A -2.57492
GLRX5 glutaredoxin 5 -2.57433
PYCARD PYD and CARD domain containing -2.56049
NME4 NME/NM23 nucleoside diphosphate kinase 4 -2.55495
ABHD14A abhydrolase domain containing 14A -2.5547
TSPAN4 tetraspanin 4 -2.54985
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -2.54648
MRGBP MRG/MORF4L binding protein -2.54594
TMEM106C transmembrane protein 106C -2.54535
MRNIP MRN complex interacting protein -2.53829
NENF neudesin neurotrophic factor -2.53823
CCNE1 cyclin E1 -2.53739
KIFC1 kinesin family member C1 -2.53545
CDC25B cell division cycle 25B -2.53136
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -2.53044
BCL7C B-cell CLL/lymphoma 7C -2.52991
SNX17 sorting nexin 17 -2.52906
ARHGAP19 Rho GTPase activating protein 19 -2.52684
UNC119B unc-119 homolog B (C. elegans) -2.52575
ZNF274 zinc finger protein 274 -2.52462
OAZ2 ornithine decarboxylase antizyme 2 -2.52053
TNNI1 troponin I type 1 (skeletal, slow) -2.5181
CCNG1 cyclin G1 -2.51295
MRPL23 mitochondrial ribosomal protein L23 -2.51041
ORC6 origin recognition complex, subunit 6 -2.503
SH3D19 SH3 domain containing 19 -2.4916
NFRKB nuclear factor related to kappaB binding protein -2.4862
MNS1 meiosis-specific nuclear structural 1 -2.48577
SCML2 sex comb on midleg-like 2 (Drosophila) -2.47858
SNF8 SNF8, ESCRT-II complex subunit -2.47656
CENPM centromere protein M -2.47351
FAM111A family with sequence similarity 111, member A -2.47303
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -2.47215
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -2.46915
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) -2.46042
HMGB2 high mobility group box 2 -2.45946
BBS1 Bardet-Biedl syndrome 1 -2.4579
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.44873
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.4464
OCA2 oculocutaneous albinism II -2.43844
GATD3 glutamine amidotransferase class 1 domain containing 3 -2.43276
EFNA4 ephrin-A4 -2.43245
ISOC2 isochorismatase domain containing 2 -2.43126
CEBPD CCAAT/enhancer binding protein (C/EBP), delta -2.42811
HMGN1 high mobility group nucleosome binding domain 1 -2.4269
OIP5 Opa interacting protein 5 -2.42005
PRMT1 protein arginine methyltransferase 1 -2.41632
COMMD4 COMM domain containing 4 -2.40474
UXT ubiquitously-expressed, prefoldin-like chaperone -2.40181
HIRA histone cell cycle regulator -2.40159
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -2.40149
NAP1L4 nucleosome assembly protein 1-like 4 -2.40127
SALL2 spalt-like transcription factor 2 -2.40085
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -2.37824
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) -2.37343
TSPAN13 tetraspanin 13 -2.37298
EXO1 exonuclease 1 -2.36825
ABAT 4-aminobutyrate aminotransferase -2.3671
VAV3 vav 3 guanine nucleotide exchange factor -2.36609
MYF6 myogenic factor 6 (herculin) -2.36458
LMAN2L lectin, mannose-binding 2-like -2.36257
PCNA proliferating cell nuclear antigen -2.36206
CERS4 ceramide synthase 4 -2.36017
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa -2.35807
THOP1 thimet oligopeptidase 1 -2.35767
HMGN3 high mobility group nucleosomal binding domain 3 -2.35576
AVPR1B arginine vasopressin receptor 1B -2.35252
AMT aminomethyltransferase -2.35181
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -2.34561
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.34184
GALK1 galactokinase 1 -2.33596
RRM2 ribonucleotide reductase M2 -2.33294
IQGAP2 IQ motif containing GTPase activating protein 2 -2.33071
MATN2 matrilin 2 -2.32113
ELOVL2 ELOVL fatty acid elongase 2 -2.31701
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -2.31212
DHRS4 dehydrogenase/reductase (SDR family) member 4 -2.31064
CDC6 cell division cycle 6 -2.30991
TRAPPC3 trafficking protein particle complex 3 -2.30628
PYGL phosphorylase, glycogen, liver -2.30601
SPPL2A signal peptide peptidase like 2A -2.30323
MYOT myotilin -2.29817
ARF5 ADP-ribosylation factor 5 -2.29782
TSEN2 TSEN2 tRNA splicing endonuclease subunit -2.29725
TMX1 thioredoxin-related transmembrane protein 1 -2.29529
SOD1 superoxide dismutase 1, soluble -2.29291
HMGN2 high mobility group nucleosomal binding domain 2 -2.28692
APOA1 apolipoprotein A-I -2.28632
HGH1 HGH1 homolog (S. cerevisiae) -2.28551
LPCAT1 lysophosphatidylcholine acyltransferase 1 -2.28524
PYCR1 pyrroline-5-carboxylate reductase 1 -2.2832
VKORC1 vitamin K epoxide reductase complex, subunit 1 -2.28245
COLGALT1 collagen beta(1-O)galactosyltransferase 1 -2.28205
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -2.27927
PHF10 PHD finger protein 10 -2.27826
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites -2.26289
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle -2.26078
SPC25 SPC25, NDC80 kinetochore complex component -2.25879
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 -2.25701
GTPBP3 GTP binding protein 3 (mitochondrial) -2.25647
GYS1 glycogen synthase 1 (muscle) -2.25572
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 -2.25527
ICMT isoprenylcysteine carboxyl methyltransferase -2.25486
CPA2 carboxypeptidase A2 (pancreatic) -2.2531
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme -2.24792
TTC38 tetratricopeptide repeat domain 38 -2.24716
PRPF19 pre-mRNA processing factor 19 -2.2464
KIF18A kinesin family member 18A -2.24528
ITGA7 integrin, alpha 7 -2.24499
CYBA cytochrome b-245, alpha polypeptide -2.23913
GMNN geminin, DNA replication inhibitor -2.23748
DPYSL2 dihydropyrimidinase-like 2 -2.23235
GPC3 glypican 3 -2.23204
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa -2.23021
PPT2 palmitoyl-protein thioesterase 2 -2.22906
NLRP4 NLR family, pyrin domain containing 4 -2.22555
KDM3A lysine (K)-specific demethylase 3A -2.2242
PPIC peptidylprolyl isomerase C (cyclophilin C) -2.22211
SPATA6 spermatogenesis associated 6 -2.21943
GSTK1 glutathione S-transferase kappa 1 -2.21718
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 -2.21563
ERCC6L excision repair cross-complementation group 6-like -2.21545
TTR transthyretin -2.21358
PRC1 protein regulator of cytokinesis 1 -2.21288
PIGF phosphatidylinositol glycan anchor biosynthesis, class F -2.21282
PMPCA peptidase (mitochondrial processing) alpha -2.20863
TLCD3A TLC domain containing 3A -2.20852
NEK11 NIMA-related kinase 11 -2.20804
PPIF peptidylprolyl isomerase F -2.20715
PPP4C protein phosphatase 4, catalytic subunit -2.20455
CLDN15 claudin 15 -2.19793
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) -2.19776
ELP5 elongator acetyltransferase complex subunit 5 -2.19646
CKAP2 cytoskeleton associated protein 2 -2.19644
ACOD1 aconitate decarboxylase 1 -2.19365
SPINK4 serine peptidase inhibitor, Kazal type 4 -2.19345
MSH2 mutS homolog 2 -2.19249
QDPR quinoid dihydropteridine reductase -2.19164
UNC119 unc-119 homolog (C. elegans) -2.1904
RIDA reactive intermediate imine deaminase A homolog -2.18475
ZCCHC24 zinc finger, CCHC domain containing 24 -2.18374
ZNF83 zinc finger protein 83 -2.17364
HMBS hydroxymethylbilane synthase -2.17174
POLE polymerase (DNA directed), epsilon, catalytic subunit -2.16426
PDF peptide deformylase (mitochondrial) -2.16334
ZNF443 zinc finger protein 443 -2.15967
LOC102724594 splicing factor U2AF 35 kDa subunit -2.15857
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) -2.15384
AURKC aurora kinase C -2.15255
DEXI Dexi homolog (mouse) -2.14961
CASQ2 calsequestrin 2 (cardiac muscle) -2.14615
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.14569
ALDH4A1 aldehyde dehydrogenase 4 family, member A1 -2.14552
FABP5 fatty acid binding protein 5 (psoriasis-associated) -2.14446
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H') -2.14387
POLR2G polymerase (RNA) II (DNA directed) polypeptide G -2.14262
ENDOG endonuclease G -2.14236
SLC38A10 solute carrier family 38, member 10 -2.14133
APOM apolipoprotein M -2.13875
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) -2.1387
RHBG Rh family, B glycoprotein (gene/pseudogene) -2.13365
RACGAP1 Rac GTPase activating protein 1 -2.13256
GSTM2 glutathione S-transferase mu 2 (muscle) -2.13164
KLHL41 kelch-like family member 41 -2.13066
GLT8D1 glycosyltransferase 8 domain containing 1 -2.13046
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 -2.12956
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.12832
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor -2.11964
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) -2.11705
COQ7 coenzyme Q7 homolog, ubiquinone (yeast) -2.11624
PARM1 prostate androgen-regulated mucin-like protein 1 -2.11461
CYB561D2 cytochrome b561 family, member D2 -2.11453
RMI1 RecQ mediated genome instability 1 -2.11369
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A -2.11265
AAAS achalasia, adrenocortical insufficiency, alacrimia -2.11238
NPTN neuroplastin -2.11154
TUBB4B tubulin, beta 4B class IVb -2.10713
CETN2 centrin, EF-hand protein, 2 -2.10632
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) -2.10615
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -2.10572
FUCA1 fucosidase, alpha-L- 1, tissue -2.10394
CFI complement factor I -2.1023
NPY neuropeptide Y -2.10174
MYL2 myosin, light chain 2, regulatory, cardiac, slow -2.09866
ATAD2 ATPase family, AAA domain containing 2 -2.09765
MRPL11 mitochondrial ribosomal protein L11 -2.0976
PARN poly(A)-specific ribonuclease -2.09728
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.09657
ECI2 enoyl-CoA delta isomerase 2 -2.09568
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) -2.09552
PEBP1 phosphatidylethanolamine binding protein 1 -2.09175
MYL11 myosin light chain 11 -2.09155
TUBG1 tubulin, gamma 1 -2.09136
CST3 cystatin C -2.0911
WDR70 WD repeat domain 70 -2.08832
SIRT3 sirtuin 3 -2.08729
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 -2.08425
CDC25A cell division cycle 25A -2.07909
MARCKSL1 MARCKS-like 1 -2.07857
CERK ceramide kinase -2.07696
MSH6 mutS homolog 6 -2.07687
HYDIN HYDIN, axonemal central pair apparatus protein -2.07363
ABHD3 abhydrolase domain containing 3 -2.07327
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -2.07305
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial -2.07264
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa -2.07261
WASF1 WAS protein family, member 1 -2.07172
IGSF1 immunoglobulin superfamily, member 1 -2.0695
ISL1 ISL LIM homeobox 1 -2.06944
TCTN2 tectonic family member 2 -2.06413
PEX11A peroxisomal biogenesis factor 11 alpha -2.06353
DYNLL1 dynein, light chain, LC8-type 1 -2.0632
CAPN10 calpain 10 -2.0625
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.0619
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) -2.06098
LYSET lysosomal enzyme trafficking factor -2.05997
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -2.0599
SLC38A3 solute carrier family 38, member 3 -2.05974
NDUFAF3 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 -2.0595
ZFTA zinc finger translocation associated -2.05841
PARPBP PARP1 binding protein -2.05839
POLK polymerase (DNA directed) kappa -2.05788
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.05446
NBPF3 neuroblastoma breakpoint family, member 3 -2.05427
VSTM4 V-set and transmembrane domain containing 4 -2.05319
SRSF3 serine/arginine-rich splicing factor 3 -2.05262
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) -2.04946
SRSF2 serine/arginine-rich splicing factor 2 -2.04946
EIF3G eukaryotic translation initiation factor 3, subunit G -2.04927
VRK1 vaccinia related kinase 1 -2.04905
ABHD17A abhydrolase domain containing 17A -2.04854
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -2.04777
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 -2.04752
UROS uroporphyrinogen III synthase -2.04653
WRAP53 WD repeat containing, antisense to TP53 -2.04214
CRTAP cartilage associated protein -2.03877
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.03629
OCEL1 occludin/ELL domain containing 1 -2.03488
RNPS1 RNA binding protein S1, serine-rich domain -2.03235
UTRN utrophin -2.03149
RPS27L ribosomal protein S27-like -2.03075
SNX1 sorting nexin 1 -2.03074
MYH2 myosin, heavy chain 2, skeletal muscle, adult -2.03024
PREB prolactin regulatory element binding -2.02948
ACTA1 actin, alpha 1, skeletal muscle -2.02875
MCM3 minichromosome maintenance complex component 3 -2.0284
ALG8 ALG8, alpha-1,3-glucosyltransferase -2.02652
STK25 serine/threonine kinase 25 -2.02579
PDGFRL platelet-derived growth factor receptor-like -2.02546
PAAF1 proteasomal ATPase-associated factor 1 -2.02541
TPM3 tropomyosin 3 -2.02473
CCDC92 coiled-coil domain containing 92 -2.02133
SCAND1 SCAN domain containing 1 -2.02064
SIVA1 SIVA1, apoptosis-inducing factor -2.01897
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 -2.01875
C2CD5 C2 calcium-dependent domain containing 5 -2.01838
MAP2K2 mitogen-activated protein kinase kinase 2 -2.01483
RNF123 ring finger protein 123 -2.01372
SEPHS1 selenophosphate synthetase 1 -2.01167
TSPAN6 tetraspanin 6 -2.00833
MYL1 myosin, light chain 1, alkali; skeletal, fast -2.0005