| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | endosulfan 20.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
65 genes differentially expressed following the CRCGN012_HEPG2_24H:G20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 6.70199 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 6.23025 |
| MOK | MOK protein kinase | 3.89904 |
| CYCS | cytochrome c, somatic | 3.5985 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 3.59438 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.52909 |
| PRKCH | protein kinase C, eta | 3.4957 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 3.44853 |
| ADRB2 | adrenoceptor beta 2, surface | 3.42631 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 3.27143 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.27037 |
| RPL39L | ribosomal protein L39-like | 3.26985 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 3.15634 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.10563 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 3.09172 |
| UBQLN2 | ubiquilin 2 | 2.86952 |
| IDE | insulin-degrading enzyme | 2.86931 |
| VGLL4 | vestigial-like family member 4 | 2.86613 |
| CSK | c-src tyrosine kinase | 2.81319 |
| E2F2 | E2F transcription factor 2 | 2.77102 |
| NOTCH1 | notch 1 | 2.73639 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.6775 |
| ZFP36 | ZFP36 ring finger protein | 2.67456 |
| INTS3 | integrator complex subunit 3 | 2.66434 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.61943 |
| HOXA10 | homeobox A10 | 2.59619 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 2.56307 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.52773 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.42807 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.41731 |
| LOC122526780 | uncharacterized LOC122526780 | 2.35774 |
| MELK | maternal embryonic leucine zipper kinase | 2.25657 |
| FZD7 | frizzled class receptor 7 | 2.25444 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | 2.04239 |
| COPS7A | COP9 signalosome subunit 7A | 2.0211 |
| INPP1 | inositol polyphosphate-1-phosphatase | 2.01662 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | -4.15092 |
| ISOC1 | isochorismatase domain containing 1 | -3.94756 |
| GTPBP8 | GTP-binding protein 8 (putative) | -3.52961 |
| CCNB1 | cyclin B1 | -3.45782 |
| LDHD | lactate dehydrogenase D | -3.28009 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.19509 |
| CDC25B | cell division cycle 25B | -3.1622 |
| GDF15 | growth differentiation factor 15 | -3.11918 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -2.99585 |
| ADI1 | acireductone dioxygenase 1 | -2.94337 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | -2.93338 |
| TRIB3 | tribbles pseudokinase 3 | -2.92745 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.92306 |
| CD320 | CD320 molecule | -2.87518 |
| TLCD3A | TLC domain containing 3A | -2.84782 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -2.84573 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.77648 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.60361 |
| WASHC4 | WASH complex subunit 4 | -2.567 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.49389 |
| GNAS | GNAS complex locus | -2.26736 |
| MEST | mesoderm specific transcript | -2.26443 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -2.22923 |
| SNX11 | sorting nexin 11 | -2.08305 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -2.06519 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.04097 |
| HMG20B | high mobility group 20B | -2.03647 |
| TCTN1 | tectonic family member 1 | -2.03353 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.01748 |
