CRCGN012_HEPG2_24H:G21 Gene Set
Genes
40 genes differentially expressed following the CRCGN012_HEPG2_24H:G21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
7.42669
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
6.29982
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
5.07834
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.14712
|
|
CSK
|
c-src tyrosine kinase
|
4.02519
|
|
MYLK
|
myosin light chain kinase
|
3.78081
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
3.77428
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.32789
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.25663
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.96314
|
|
RPL39L
|
ribosomal protein L39-like
|
2.78993
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.742
|
|
STAP2
|
signal transducing adaptor family member 2
|
2.50941
|
|
HOXA10
|
homeobox A10
|
2.41576
|
|
TLR4
|
toll-like receptor 4
|
2.36442
|
|
PRKCH
|
protein kinase C, eta
|
2.22211
|
|
PMM2
|
phosphomannomutase 2
|
2.12505
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.1164
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
2.10252
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.08706
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-5.16382
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
-4.21154
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.50845
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.19876
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.19472
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.13057
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-2.982
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.93107
|
|
TCTN1
|
tectonic family member 1
|
-2.87451
|
|
GNAS
|
GNAS complex locus
|
-2.66124
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-2.62285
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.53338
|
|
CCDC86
|
coiled-coil domain containing 86
|
-2.45528
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.44588
|
|
SCAND1
|
SCAN domain containing 1
|
-2.35929
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.34473
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-2.30126
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-2.29406
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.19378
|
|
RPS5
|
ribosomal protein S5
|
-2.01133
|
