CRCGN012_HEPG2_24H:G23 Gene Set
Genes
53 genes differentially expressed following the CRCGN012_HEPG2_24H:G23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
6.47365
|
|
UBQLN2
|
ubiquilin 2
|
6.32633
|
|
LOC122526780
|
uncharacterized LOC122526780
|
4.48549
|
|
MAMLD1
|
mastermind-like domain containing 1
|
4.06288
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
4.0113
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
3.58048
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.55452
|
|
KLHL21
|
kelch-like family member 21
|
3.46435
|
|
CHEK2
|
checkpoint kinase 2
|
3.35034
|
|
DHX29
|
DEAH (Asp-Glu-Ala-His) box polypeptide 29
|
3.30023
|
|
HOXA10
|
homeobox A10
|
3.29721
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.27
|
|
E2F2
|
E2F transcription factor 2
|
3.11274
|
|
CBR3
|
carbonyl reductase 3
|
2.97911
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.92493
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.8308
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.7852
|
|
STIMATE
|
STIM activating enhancer
|
2.75854
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.62299
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.55838
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.44432
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.22602
|
|
CYCS
|
cytochrome c, somatic
|
2.2083
|
|
PIH1D1
|
PIH1 domain containing 1
|
2.19812
|
|
LRP3
|
low density lipoprotein receptor-related protein 3
|
2.10141
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.08112
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.51921
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-5.37383
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.54062
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.05351
|
|
NCK1
|
NCK adaptor protein 1
|
-3.74908
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.7084
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.58028
|
|
LDHD
|
lactate dehydrogenase D
|
-3.53379
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.52216
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-3.36205
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.32914
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.29961
|
|
CCNB2
|
cyclin B2
|
-3.22844
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.18497
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
-2.88333
|
|
CD58
|
CD58 molecule
|
-2.67772
|
|
ZW10
|
zw10 kinetochore protein
|
-2.67281
|
|
STMN1
|
stathmin 1
|
-2.60149
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.51029
|
|
SESN1
|
sestrin 1
|
-2.20706
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-2.16339
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.16292
|
|
ALKBH1
|
alkB, alkylation repair homolog 1 (E. coli)
|
-2.08262
|
|
PGM1
|
phosphoglucomutase 1
|
-2.06747
|
|
NVL
|
nuclear VCP-like
|
-2.06147
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
-2.05942
|
|
EGF
|
epidermal growth factor
|
-2.05355
|
