CRCGN012_HEPG2_24H:G24 Gene Set
Genes
57 genes differentially expressed following the CRCGN012_HEPG2_24H:G24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ATP11B
|
ATPase, class VI, type 11B
|
7.52385
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
6.97844
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
6.90721
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
6.85772
|
|
CSK
|
c-src tyrosine kinase
|
5.92321
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.85127
|
|
CHN1
|
chimerin 1
|
4.09167
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.01563
|
|
ZNF589
|
zinc finger protein 589
|
3.53186
|
|
MAMLD1
|
mastermind-like domain containing 1
|
3.33893
|
|
STIMATE
|
STIM activating enhancer
|
3.10294
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
3.06791
|
|
RRAGA
|
Ras-related GTP binding A
|
3.04701
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.01992
|
|
NFKBIE
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
|
3.00925
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.76424
|
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
2.70763
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.62702
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.61743
|
|
HOXA10
|
homeobox A10
|
2.59668
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.40625
|
|
TLR4
|
toll-like receptor 4
|
2.19988
|
|
PCNA
|
proliferating cell nuclear antigen
|
2.16469
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.07831
|
|
ATP4B
|
ATPase, H+/K+ exchanging, beta polypeptide
|
2.07522
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.0262
|
|
NRDC
|
nardilysin convertase
|
2.01478
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
GDF15
|
growth differentiation factor 15
|
-5.8442
|
|
CCNB2
|
cyclin B2
|
-5.34897
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.39227
|
|
TRIB3
|
tribbles pseudokinase 3
|
-4.12438
|
|
PEG10
|
paternally expressed 10
|
-3.8702
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.78026
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
-3.286
|
|
ZNF586
|
zinc finger protein 586
|
-3.26625
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.26061
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.22071
|
|
TUBB6
|
tubulin, beta 6 class V
|
-3.1349
|
|
DSG2
|
desmoglein 2
|
-3.0823
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-3.02605
|
|
LAP3
|
leucine aminopeptidase 3
|
-2.95999
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.89453
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.83888
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.82379
|
|
GNAS
|
GNAS complex locus
|
-2.58396
|
|
CD58
|
CD58 molecule
|
-2.56649
|
|
WASHC4
|
WASH complex subunit 4
|
-2.47301
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.32057
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.24513
|
|
CRYZ
|
crystallin, zeta (quinone reductase)
|
-2.2237
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.18615
|
|
APOA4
|
apolipoprotein A-IV
|
-2.1761
|
|
HELZ
|
helicase with zinc finger
|
-2.17324
|
|
ARVCF
|
armadillo repeat gene deleted in velocardiofacial syndrome
|
-2.06498
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
-2.05294
|
|
CTNND1
|
catenin (cadherin-associated protein), delta 1
|
-2.04622
|
|
CD82
|
CD82 molecule
|
-2.01328
|
