| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 1-amino-2-methylanthraquinone 4.95 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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52 genes differentially expressed following the CRCGN012_HEPG2_24H:H04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 4.57534 |
| ADAM10 | ADAM metallopeptidase domain 10 | 4.49966 |
| AMDHD2 | amidohydrolase domain containing 2 | 4.39497 |
| PNKP | polynucleotide kinase 3'-phosphatase | 4.37862 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.13426 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.10403 |
| STIMATE | STIM activating enhancer | 3.95131 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 3.82738 |
| HOXA10 | homeobox A10 | 3.7348 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 3.53135 |
| CBR3 | carbonyl reductase 3 | 3.18555 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 3.12036 |
| LCN2 | lipocalin 2 | 3.09913 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.08729 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.89082 |
| CSK | c-src tyrosine kinase | 2.73017 |
| LOC122526780 | uncharacterized LOC122526780 | 2.71268 |
| PFKL | phosphofructokinase, liver | 2.69211 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.65757 |
| GPATCH8 | G patch domain containing 8 | 2.577 |
| MTA2 | metastasis associated 1 family, member 2 | 2.48875 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 2.21348 |
| PCNP | PEST proteolytic signal containing nuclear protein | 2.19279 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.11665 |
| GATA3 | GATA binding protein 3 | 2.11377 |
| JADE2 | jade family PHD finger 2 | 2.10902 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 2.08537 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.02356 |
| VAT1 | vesicle amine transport 1 | 2.00801 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.85161 |
| LDHD | lactate dehydrogenase D | -4.27963 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -4.21771 |
| PEG10 | paternally expressed 10 | -3.75805 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.7057 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -3.2807 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.16554 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.04441 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -3.02903 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -2.99234 |
| THAP11 | THAP domain containing 11 | -2.9821 |
| GNAS | GNAS complex locus | -2.94755 |
| CCNB1 | cyclin B1 | -2.72654 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.57257 |
| EGF | epidermal growth factor | -2.23386 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -2.22632 |
| SLC35A1 | solute carrier family 35 (CMP-sialic acid transporter), member A1 | -2.17638 |
| PCMT1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase | -2.07025 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -2.06493 |
| ZW10 | zw10 kinetochore protein | -2.04639 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -2.04295 |
| FKBP4 | FK506 binding protein 4, 59kDa | -2.01474 |
| TSPAN4 | tetraspanin 4 | -2.01031 |
