CRCGN012_HEPG2_24H:H05 Gene Set
Genes
46 genes differentially expressed following the CRCGN012_HEPG2_24H:H05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
6.24674
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
5.5655
|
|
DRAP1
|
DR1-associated protein 1 (negative cofactor 2 alpha)
|
4.04975
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.7355
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.57101
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.56681
|
|
JADE2
|
jade family PHD finger 2
|
3.49967
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
3.29587
|
|
UBQLN2
|
ubiquilin 2
|
3.2034
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.03621
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
2.79303
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.73154
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.72609
|
|
CHN1
|
chimerin 1
|
2.70646
|
|
E2F2
|
E2F transcription factor 2
|
2.69307
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.61143
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.59362
|
|
RRAGA
|
Ras-related GTP binding A
|
2.4971
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.33991
|
|
KIF14
|
kinesin family member 14
|
2.26004
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.25992
|
|
CBR3
|
carbonyl reductase 3
|
2.16265
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
2.14076
|
|
COPZ1
|
coatomer protein complex, subunit zeta 1
|
2.13311
|
|
VAT1
|
vesicle amine transport 1
|
2.1029
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-8.50758
|
|
LDHD
|
lactate dehydrogenase D
|
-6.87874
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-6.77635
|
|
SPAG4
|
sperm associated antigen 4
|
-3.64439
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.55914
|
|
LAP3
|
leucine aminopeptidase 3
|
-3.54893
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.26799
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.17073
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.10243
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.91072
|
|
COG2
|
component of oligomeric golgi complex 2
|
-2.76461
|
|
ILK
|
integrin-linked kinase
|
-2.59992
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.50439
|
|
CDC25B
|
cell division cycle 25B
|
-2.46271
|
|
CDC20
|
cell division cycle 20
|
-2.35681
|
|
NVL
|
nuclear VCP-like
|
-2.30262
|
|
SLC12A8
|
solute carrier family 12, member 8
|
-2.2811
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.24946
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.18309
|
|
RHEB
|
Ras homolog enriched in brain
|
-2.18094
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-2.08115
|
