| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | BRD-K88965984 5.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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64 genes differentially expressed following the CRCGN012_HEPG2_24H:H10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 6.26027 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 6.11804 |
| STIMATE | STIM activating enhancer | 6.02826 |
| AMDHD2 | amidohydrolase domain containing 2 | 5.96305 |
| CCL2 | chemokine (C-C motif) ligand 2 | 5.53227 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 4.21017 |
| EGF | epidermal growth factor | 4.11973 |
| ADRB2 | adrenoceptor beta 2, surface | 4.11655 |
| ATP11B | ATPase, class VI, type 11B | 4.06837 |
| MAMLD1 | mastermind-like domain containing 1 | 4.03035 |
| ABHD4 | abhydrolase domain containing 4 | 3.94126 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 3.814 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.78468 |
| STK10 | serine/threonine kinase 10 | 3.76056 |
| E2F2 | E2F transcription factor 2 | 3.51052 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.44071 |
| EVL | Enah/Vasp-like | 3.1624 |
| GATA3 | GATA binding protein 3 | 3.13152 |
| MYLK | myosin light chain kinase | 2.84767 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 2.673 |
| CHN1 | chimerin 1 | 2.66151 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 2.60126 |
| TNP1 | transition protein 1 (during histone to protamine replacement) | 2.58766 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 2.5612 |
| LCN2 | lipocalin 2 | 2.45839 |
| LOC122526780 | uncharacterized LOC122526780 | 2.42854 |
| ANO10 | anoctamin 10 | 2.37526 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.25094 |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin | 2.22193 |
| MAP7 | microtubule-associated protein 7 | 2.12882 |
| DIPK1A | divergent protein kinase domain 1A | 2.10424 |
| CCNO | cyclin O | 2.03527 |
| SORBS1 | sorbin and SH3 domain containing 1 | 2.03299 |
| PRM2 | protamine 2 | 2.03259 |
| CBARP | CACN subunit beta associated regulatory protein | 2.02641 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 2.0202 |
| CCDC70 | coiled-coil domain containing 70 | 2.00084 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -5.99638 |
| PCNA | proliferating cell nuclear antigen | -4.81706 |
| CD320 | CD320 molecule | -3.98014 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.91339 |
| MRPS2 | mitochondrial ribosomal protein S2 | -3.79235 |
| TRIB3 | tribbles pseudokinase 3 | -3.76511 |
| ANKRD10 | ankyrin repeat domain 10 | -3.40071 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -3.37782 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.05669 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.92918 |
| NGRN | neugrin, neurite outgrowth associated | -2.89755 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.7524 |
| GNAS | GNAS complex locus | -2.70445 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.70228 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.64057 |
| SNX11 | sorting nexin 11 | -2.58666 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -2.37993 |
| CCNB2 | cyclin B2 | -2.26125 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -2.21227 |
| CHMP4B | charged multivesicular body protein 4B | -2.2002 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.15109 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.12727 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 | -2.1235 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.05197 |
| RGS2 | regulator of G-protein signaling 2 | -2.04365 |
| ZFHX4 | zinc finger homeobox 4 | -2.01359 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -2.0098 |
