CRCGN012_HEPG2_24H:H11 Gene Set
Genes
44 genes differentially expressed following the CRCGN012_HEPG2_24H:H11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
E2F2
|
E2F transcription factor 2
|
5.98584
|
|
CYCS
|
cytochrome c, somatic
|
5.29162
|
|
CHN1
|
chimerin 1
|
5.15113
|
|
PRR15L
|
proline rich 15-like
|
4.97208
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.47337
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.33073
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.20605
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.93931
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.89346
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.70401
|
|
MOK
|
MOK protein kinase
|
3.49961
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.36598
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.33234
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.19009
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.14782
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.05822
|
|
STXBP2
|
syntaxin binding protein 2
|
2.90137
|
|
GATA3
|
GATA binding protein 3
|
2.71442
|
|
EVL
|
Enah/Vasp-like
|
2.56921
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
2.4654
|
|
ZNF589
|
zinc finger protein 589
|
2.30887
|
|
LCN2
|
lipocalin 2
|
2.09599
|
|
DDX39A
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
|
2.09286
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.07786
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-4.43689
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.39565
|
|
VAT1
|
vesicle amine transport 1
|
-4.38242
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-4.31868
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-4.2788
|
|
LDHD
|
lactate dehydrogenase D
|
-4.27484
|
|
THAP11
|
THAP domain containing 11
|
-4.2311
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-4.20273
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.50866
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.2392
|
|
FASTKD5
|
FAST kinase domains 5
|
-3.22104
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-3.16681
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-3.01431
|
|
NUP62
|
nucleoporin 62kDa
|
-2.95817
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.61393
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.55445
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
-2.29934
|
|
EGF
|
epidermal growth factor
|
-2.17313
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.14356
|
|
SESN1
|
sestrin 1
|
-2.11023
|
