| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | BRD-K88965984 1.25 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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68 genes differentially expressed following the CRCGN012_HEPG2_24H:H12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 6.84608 |
| ADRB2 | adrenoceptor beta 2, surface | 5.98543 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 4.32276 |
| CSK | c-src tyrosine kinase | 3.88718 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 3.58629 |
| STIMATE | STIM activating enhancer | 3.49702 |
| E2F2 | E2F transcription factor 2 | 3.45583 |
| NMU | neuromedin U | 3.42336 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 3.33573 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 3.30245 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.21262 |
| UBQLN2 | ubiquilin 2 | 3.20813 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.16695 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 3.15935 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.04437 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.03559 |
| BZW2 | basic leucine zipper and W2 domains 2 | 2.8868 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 2.86412 |
| MYLK | myosin light chain kinase | 2.69994 |
| EPN2 | epsin 2 | 2.65144 |
| PLS1 | plastin 1 | 2.63981 |
| MOK | MOK protein kinase | 2.61471 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.61228 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | 2.61142 |
| CHMP6 | charged multivesicular body protein 6 | 2.61055 |
| CYCS | cytochrome c, somatic | 2.49551 |
| CCNF | cyclin F | 2.32217 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.25361 |
| PDLIM3 | PDZ and LIM domain 3 | 2.19318 |
| NOSIP | nitric oxide synthase interacting protein | 2.18773 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.15692 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.15617 |
| FAM184A | family with sequence similarity 184, member A | 2.13958 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.11825 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.09503 |
| HBD | hemoglobin, delta | 2.09335 |
| ZNF778 | zinc finger protein 778 | 2.03415 |
| IFI44L | interferon-induced protein 44-like | 2.02238 |
| PRR15L | proline rich 15-like | 2.00598 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -6.85996 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -6.76613 |
| SLC35F2 | solute carrier family 35, member F2 | -6.50735 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.83068 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.73626 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -3.53613 |
| VAT1 | vesicle amine transport 1 | -3.53212 |
| SMNDC1 | survival motor neuron domain containing 1 | -3.49116 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.46805 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.44712 |
| LDHD | lactate dehydrogenase D | -3.33557 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.12008 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.50711 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.50495 |
| RBM6 | RNA binding motif protein 6 | -2.46978 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.38603 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.33324 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.29179 |
| GLOD4 | glyoxalase domain containing 4 | -2.26665 |
| RNF167 | ring finger protein 167 | -2.25692 |
| IPO13 | importin 13 | -2.24346 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.19688 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.16752 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.14144 |
| CDC25B | cell division cycle 25B | -2.13853 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain | -2.12889 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.12731 |
| CD320 | CD320 molecule | -2.04356 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -2.01334 |
