| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | scopolamine hydrobromide tri-hydrate 40.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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53 genes differentially expressed following the CRCGN012_HEPG2_24H:H13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPER1 | G protein-coupled estrogen receptor 1 | 5.16771 |
| E2F2 | E2F transcription factor 2 | 5.10613 |
| ADRB2 | adrenoceptor beta 2, surface | 4.94494 |
| MAMLD1 | mastermind-like domain containing 1 | 4.80574 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.74966 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.13771 |
| CBR3 | carbonyl reductase 3 | 3.90136 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.85905 |
| PRR15L | proline rich 15-like | 3.85884 |
| CSK | c-src tyrosine kinase | 3.83873 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 3.77925 |
| CHMP6 | charged multivesicular body protein 6 | 3.66969 |
| IDE | insulin-degrading enzyme | 3.63691 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.51821 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.44642 |
| CHN1 | chimerin 1 | 2.81486 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.80602 |
| EVL | Enah/Vasp-like | 2.64922 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 2.60512 |
| MAP7 | microtubule-associated protein 7 | 2.58921 |
| GATA3 | GATA binding protein 3 | 2.56991 |
| LOC122526780 | uncharacterized LOC122526780 | 2.55173 |
| TBXA2R | thromboxane A2 receptor | 2.53358 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 2.3635 |
| ECD | ecdysoneless homolog (Drosophila) | 2.28344 |
| IGSF1 | immunoglobulin superfamily, member 1 | 2.14981 |
| PTH2R | parathyroid hormone 2 receptor | 2.0609 |
| SOCS2 | suppressor of cytokine signaling 2 | 2.02454 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 2.00267 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -6.6042 |
| MRPS2 | mitochondrial ribosomal protein S2 | -5.12819 |
| ZNF586 | zinc finger protein 586 | -4.96274 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.82622 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -4.5088 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -4.36301 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -4.27917 |
| WASHC4 | WASH complex subunit 4 | -3.89251 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.86066 |
| GDF15 | growth differentiation factor 15 | -3.80874 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.36469 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -3.23783 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.17919 |
| CAB39 | calcium binding protein 39 | -2.84738 |
| RNF167 | ring finger protein 167 | -2.71893 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.56582 |
| ZNF761 | zinc finger protein 761 | -2.44013 |
| SLC35F2 | solute carrier family 35, member F2 | -2.40368 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.20682 |
| ZNF587B | zinc finger protein 587B | -2.15429 |
| ZNF304 | zinc finger protein 304 | -2.11755 |
| EGF | epidermal growth factor | -2.08587 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -2.07225 |
| PRPF4 | pre-mRNA processing factor 4 | -2.02199 |
