CRCGN012_HEPG2_24H:H16 Gene Set
Genes
53 genes differentially expressed following the CRCGN012_HEPG2_24H:H16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
EAPP
|
E2F-associated phosphoprotein
|
6.25604
|
|
NMU
|
neuromedin U
|
5.71475
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.04327
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.92063
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
4.47222
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
3.92861
|
|
SMIM40
|
small integral membrane protein 40
|
3.85088
|
|
TESK1
|
testis-specific kinase 1
|
3.72787
|
|
UBQLN2
|
ubiquilin 2
|
3.72361
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.57125
|
|
PRKCH
|
protein kinase C, eta
|
3.56705
|
|
JADE2
|
jade family PHD finger 2
|
3.45704
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.2579
|
|
SATB1
|
SATB homeobox 1
|
3.19616
|
|
CCNA1
|
cyclin A1
|
2.74392
|
|
ZNF589
|
zinc finger protein 589
|
2.7339
|
|
CHN1
|
chimerin 1
|
2.71819
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.67748
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.56654
|
|
CEP57
|
centrosomal protein 57kDa
|
2.40233
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.34443
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
2.30765
|
|
LCN2
|
lipocalin 2
|
2.29721
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
2.24343
|
|
TLR4
|
toll-like receptor 4
|
2.11045
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.09266
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.07265
|
|
PCNA
|
proliferating cell nuclear antigen
|
2.05918
|
|
LRRC59
|
leucine rich repeat containing 59
|
2.04617
|
|
CNTRL
|
centriolin
|
2.038
|
|
JRKL
|
JRK-like
|
2.00554
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-8.17368
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-5.70466
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-4.74798
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.63506
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-3.97582
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.76929
|
|
GDF15
|
growth differentiation factor 15
|
-3.63571
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.5147
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.26944
|
|
VAT1
|
vesicle amine transport 1
|
-3.25861
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.11597
|
|
CDC25B
|
cell division cycle 25B
|
-2.92639
|
|
EGF
|
epidermal growth factor
|
-2.84602
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.78629
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.77037
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.76498
|
|
CCNB1
|
cyclin B1
|
-2.43963
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-2.24104
|
|
KBTBD2
|
kelch repeat and BTB (POZ) domain containing 2
|
-2.18645
|
|
TBCA
|
tubulin folding cofactor A
|
-2.06942
|
|
FKBP9
|
FK506 binding protein 9, 63 kDa
|
-2.02346
|
|
HSPA2
|
heat shock 70kDa protein 2
|
-2.01205
|
