| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | scopolamine hydrobromide tri-hydrate 2.5 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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62 genes differentially expressed following the CRCGN012_HEPG2_24H:H17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 6.37338 |
| PNKP | polynucleotide kinase 3'-phosphatase | 5.90012 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 5.74674 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 4.92537 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.9113 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.75889 |
| UBQLN2 | ubiquilin 2 | 4.25835 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 4.13647 |
| CBR3 | carbonyl reductase 3 | 4.03733 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.96446 |
| MYLK | myosin light chain kinase | 3.92725 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.71978 |
| CCNF | cyclin F | 3.66544 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.64558 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 3.60201 |
| TAC4 | tachykinin 4 (hemokinin) | 3.58646 |
| ABHD6 | abhydrolase domain containing 6 | 3.50396 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 3.39884 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.35988 |
| R3HDM2 | R3H domain containing 2 | 2.39505 |
| DNMBP | dynamin binding protein | 2.38007 |
| KIF14 | kinesin family member 14 | 2.37427 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.35904 |
| RPA3 | replication protein A3, 14kDa | 2.2723 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.20021 |
| TXNL4B | thioredoxin-like 4B | 2.16915 |
| EXO1 | exonuclease 1 | 2.16656 |
| TMEM164 | transmembrane protein 164 | 2.15985 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.14986 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.14896 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 2.14821 |
| TBC1D17 | TBC1 domain family, member 17 | 2.14502 |
| LOC122526780 | uncharacterized LOC122526780 | 2.12686 |
| RAD51C | RAD51 paralog C | 2.12635 |
| SPC25 | SPC25, NDC80 kinetochore complex component | 2.08991 |
| MX1 | MX dynamin-like GTPase 1 | 2.07262 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -7.46189 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -5.2366 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -4.96495 |
| CDC20 | cell division cycle 20 | -4.95919 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.66674 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.54335 |
| GNAS | GNAS complex locus | -3.74457 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -3.67913 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -3.65927 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.63221 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.47326 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa | -3.44637 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.15832 |
| VDAC1 | voltage-dependent anion channel 1 | -2.99562 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -2.944 |
| IFRD2 | interferon-related developmental regulator 2 | -2.84779 |
| CPNE3 | copine III | -2.72656 |
| TLCD3A | TLC domain containing 3A | -2.583 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | -2.28363 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -2.11166 |
| PCDHB13 | protocadherin beta 13 | -2.09707 |
| CASP8AP2 | caspase 8 associated protein 2 | -2.07724 |
| WDR46 | WD repeat domain 46 | -2.04414 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.03155 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) | -2.01263 |
| RNF130 | ring finger protein 130 | -2.00838 |
