CRCGN012_HEPG2_24H:H20 Gene Set
Genes
40 genes differentially expressed following the CRCGN012_HEPG2_24H:H20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
EPHB2
|
EPH receptor B2
|
4.21909
|
|
ABHD4
|
abhydrolase domain containing 4
|
4.11431
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.03664
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
3.15385
|
|
PRKCH
|
protein kinase C, eta
|
2.99857
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
2.95373
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.73685
|
|
CSK
|
c-src tyrosine kinase
|
2.71261
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.53742
|
|
JADE2
|
jade family PHD finger 2
|
2.52073
|
|
TLR4
|
toll-like receptor 4
|
2.4383
|
|
DHDDS
|
dehydrodolichyl diphosphate synthase
|
2.3782
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
2.31371
|
|
E2F2
|
E2F transcription factor 2
|
2.2988
|
|
MAPKAPK2
|
mitogen-activated protein kinase-activated protein kinase 2
|
2.27952
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
2.22834
|
|
PFKL
|
phosphofructokinase, liver
|
2.16209
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
2.13617
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.13318
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-8.66902
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-7.17884
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.16467
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.84141
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.8291
|
|
GOLT1B
|
golgi transport 1B
|
-3.67736
|
|
CDC20
|
cell division cycle 20
|
-3.62423
|
|
ZNF586
|
zinc finger protein 586
|
-3.51125
|
|
LAP3
|
leucine aminopeptidase 3
|
-3.45863
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.88798
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.7545
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.59524
|
|
RAI14
|
retinoic acid induced 14
|
-2.50569
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.48127
|
|
PSRC1
|
proline/serine-rich coiled-coil 1
|
-2.41759
|
|
DNM1L
|
dynamin 1-like
|
-2.38548
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.37197
|
|
MAP7
|
microtubule-associated protein 7
|
-2.31145
|
|
PEG10
|
paternally expressed 10
|
-2.26348
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.15137
|
|
EGF
|
epidermal growth factor
|
-2.10065
|
