CRCGN012_HEPG2_24H:H21 Gene Set
Genes
32 genes differentially expressed following the CRCGN012_HEPG2_24H:H21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.99824
|
|
GNAI2
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
|
3.7969
|
|
MYLK
|
myosin light chain kinase
|
3.65213
|
|
CBR3
|
carbonyl reductase 3
|
3.55467
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.48272
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.38321
|
|
ABHD4
|
abhydrolase domain containing 4
|
3.37981
|
|
MAMLD1
|
mastermind-like domain containing 1
|
3.32844
|
|
LCN2
|
lipocalin 2
|
3.16968
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.79646
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
2.59188
|
|
PCDHB11
|
protocadherin beta 11
|
2.53957
|
|
NMU
|
neuromedin U
|
2.4428
|
|
EVL
|
Enah/Vasp-like
|
2.4119
|
|
TEX10
|
testis expressed 10
|
2.41178
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.3969
|
|
STK10
|
serine/threonine kinase 10
|
2.34867
|
|
HDGFL3
|
HDGF like 3
|
2.24689
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.11959
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.60664
|
|
PCNA
|
proliferating cell nuclear antigen
|
-5.56936
|
|
VAT1
|
vesicle amine transport 1
|
-3.75471
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.68225
|
|
DNTTIP2
|
deoxynucleotidyltransferase, terminal, interacting protein 2
|
-3.46071
|
|
RPIA
|
ribose 5-phosphate isomerase A
|
-3.25835
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.17915
|
|
WASHC4
|
WASH complex subunit 4
|
-3.0669
|
|
ZNF586
|
zinc finger protein 586
|
-2.89929
|
|
CCNB2
|
cyclin B2
|
-2.8185
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.4485
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.40072
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.15062
|
