CRCGN012_HEPG2_24H:H23 Gene Set
Genes
38 genes differentially expressed following the CRCGN012_HEPG2_24H:H23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
5.10145
|
|
NOTCH1
|
notch 1
|
4.79854
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.54107
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
3.46531
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.45718
|
|
UBQLN2
|
ubiquilin 2
|
3.44641
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.39675
|
|
CSK
|
c-src tyrosine kinase
|
3.32845
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.28868
|
|
ADGRG1
|
adhesion G protein-coupled receptor G1
|
2.75255
|
|
PHKG2
|
phosphorylase kinase, gamma 2 (testis)
|
2.75242
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.67631
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.65298
|
|
EPHA3
|
EPH receptor A3
|
2.4946
|
|
CBR3
|
carbonyl reductase 3
|
2.3462
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.32002
|
|
CCNA1
|
cyclin A1
|
2.25228
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
2.17663
|
|
E2F8
|
E2F transcription factor 8
|
2.05196
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
2.03472
|
|
MAP7
|
microtubule-associated protein 7
|
2.03295
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.02251
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.63293
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-6.24493
|
|
CCNB1
|
cyclin B1
|
-5.39256
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-5.02331
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.96507
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-4.55592
|
|
CTSD
|
cathepsin D
|
-3.49317
|
|
CCNB2
|
cyclin B2
|
-3.4569
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-3.41656
|
|
CDC20
|
cell division cycle 20
|
-3.16651
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.06854
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.91372
|
|
PEG10
|
paternally expressed 10
|
-2.69123
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.20895
|
|
MACF1
|
microtubule-actin crosslinking factor 1
|
-2.1854
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.11221
|
