CRCGN012_HEPG2_24H:I01 Gene Set
Genes
44 genes differentially expressed following the CRCGN012_HEPG2_24H:I01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CSK
|
c-src tyrosine kinase
|
7.69526
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
5.75222
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.25922
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
5.09496
|
|
ZNF589
|
zinc finger protein 589
|
5.0061
|
|
PRR15L
|
proline rich 15-like
|
4.98652
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
4.87743
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.7773
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.70513
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
4.16239
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.3455
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.1919
|
|
CHN1
|
chimerin 1
|
2.82322
|
|
EPHB2
|
EPH receptor B2
|
2.81732
|
|
JADE2
|
jade family PHD finger 2
|
2.35177
|
|
ZFP36
|
ZFP36 ring finger protein
|
2.31442
|
|
TLR4
|
toll-like receptor 4
|
2.2596
|
|
CPSF7
|
cleavage and polyadenylation specific factor 7, 59kDa
|
2.1402
|
|
SLC15A3
|
solute carrier family 15 (oligopeptide transporter), member 3
|
2.1257
|
|
ALPL
|
alkaline phosphatase, liver/bone/kidney
|
2.1081
|
|
GRIP2
|
glutamate receptor interacting protein 2
|
2.02839
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-5.25764
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-4.29567
|
|
EGF
|
epidermal growth factor
|
-4.27597
|
|
COG7
|
component of oligomeric golgi complex 7
|
-3.94659
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-3.71221
|
|
CDC20
|
cell division cycle 20
|
-3.68046
|
|
FASTKD5
|
FAST kinase domains 5
|
-3.44097
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-3.38689
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.21816
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.17358
|
|
GNAS
|
GNAS complex locus
|
-3.13639
|
|
DUSP11
|
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
|
-2.68706
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
-2.37945
|
|
ID2
|
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
|
-2.23969
|
|
NVL
|
nuclear VCP-like
|
-2.21823
|
|
USP36
|
ubiquitin specific peptidase 36
|
-2.10645
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.10402
|
|
CLN8
|
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
|
-2.08841
|
|
CCP110
|
centriolar coiled coil protein 110kDa
|
-2.08063
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
-2.06582
|
|
MPV17L-BMERB1
|
MPV17L-BMERB1 readthrough
|
-2.05057
|
|
IPP
|
intracisternal A particle-promoted polypeptide
|
-2.01827
|
|
RBM6
|
RNA binding motif protein 6
|
-2.01412
|
