| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | penicillin-v-potassium 10.3 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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62 genes differentially expressed following the CRCGN012_HEPG2_24H:I02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 7.83378 |
| EPHB2 | EPH receptor B2 | 4.97972 |
| NFIL3 | nuclear factor, interleukin 3 regulated | 4.73687 |
| NOTCH1 | notch 1 | 4.33914 |
| LCN2 | lipocalin 2 | 4.33638 |
| LOC122526780 | uncharacterized LOC122526780 | 4.15078 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 3.83169 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.73314 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.69077 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.57773 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 3.56441 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 3.36366 |
| EPHA3 | EPH receptor A3 | 3.27962 |
| LPAR2 | lysophosphatidic acid receptor 2 | 3.06172 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 3.03701 |
| CBR3 | carbonyl reductase 3 | 3.03664 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 2.74079 |
| TLR4 | toll-like receptor 4 | 2.69831 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.68272 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.66443 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.65541 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.53331 |
| PMM2 | phosphomannomutase 2 | 2.45585 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 2.36273 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.25783 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 2.20407 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 2.17304 |
| RGPD2 | RANBP2-like and GRIP domain containing 2 | 2.16406 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.15273 |
| WASF3 | WAS protein family, member 3 | 2.08016 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 2.01138 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -6.1262 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -5.44546 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -5.38114 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -5.12542 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.94618 |
| TLCD3A | TLC domain containing 3A | -4.07631 |
| TRIB3 | tribbles pseudokinase 3 | -3.90461 |
| HMG20B | high mobility group 20B | -3.65718 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -3.60371 |
| RAI14 | retinoic acid induced 14 | -3.59034 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.47803 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -3.47009 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.42591 |
| ADI1 | acireductone dioxygenase 1 | -3.21221 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.94631 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.91528 |
| CCNB2 | cyclin B2 | -2.90721 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.61521 |
| RNF167 | ring finger protein 167 | -2.59152 |
| SSBP2 | single-stranded DNA binding protein 2 | -2.54018 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.43372 |
| KIFAP3 | kinesin-associated protein 3 | -2.24006 |
| FJX1 | four jointed box 1 (Drosophila) | -2.15746 |
| PMCH | pro-melanin-concentrating hormone | -2.14304 |
| HOXD9 | homeobox D9 | -2.13018 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -2.09809 |
| IPO13 | importin 13 | -2.08115 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.07018 |
| WDR7 | WD repeat domain 7 | -2.05299 |
| HOXD10 | homeobox D10 | -2.01576 |
| POT1 | protection of telomeres 1 | -2.00938 |
