CRCGN012_HEPG2_24H:I03 Gene Set
Genes
51 genes differentially expressed following the CRCGN012_HEPG2_24H:I03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
UBQLN2
|
ubiquilin 2
|
10.0
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
7.56254
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
4.86909
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
4.78761
|
|
CYCS
|
cytochrome c, somatic
|
4.3302
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.25425
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.18478
|
|
RPL39L
|
ribosomal protein L39-like
|
4.08794
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.68562
|
|
HOXA10
|
homeobox A10
|
3.6671
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.59868
|
|
H2BC12
|
H2B clustered histone 12
|
3.5781
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.56276
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.34308
|
|
MAMLD1
|
mastermind-like domain containing 1
|
3.2664
|
|
CHEK2
|
checkpoint kinase 2
|
3.24952
|
|
SFTPB
|
surfactant protein B
|
3.24366
|
|
E2F2
|
E2F transcription factor 2
|
3.2362
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
3.13196
|
|
JADE2
|
jade family PHD finger 2
|
3.11978
|
|
CHN1
|
chimerin 1
|
3.05816
|
|
NOTCH1
|
notch 1
|
2.83011
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.77397
|
|
METTL16
|
methyltransferase like 16
|
2.25938
|
|
ZMYM3
|
zinc finger, MYM-type 3
|
2.15981
|
|
PARG
|
poly (ADP-ribose) glycohydrolase
|
2.06434
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.01988
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.01246
|
|
SQOR
|
sulfide quinone oxidoreductase
|
2.01113
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-10.0
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-7.95047
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-5.78224
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.97501
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.77907
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-3.50606
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.43551
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.36449
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.25136
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.23934
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.92432
|
|
MMP8
|
matrix metallopeptidase 8
|
-2.7245
|
|
GNAS
|
GNAS complex locus
|
-2.52135
|
|
CTNND1
|
catenin (cadherin-associated protein), delta 1
|
-2.43551
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-2.38147
|
|
SESN1
|
sestrin 1
|
-2.27136
|
|
POLR3F
|
polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
|
-2.25616
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.24083
|
|
GDF15
|
growth differentiation factor 15
|
-2.22185
|
|
LRRC41
|
leucine rich repeat containing 41
|
-2.21018
|
|
GSTO1
|
glutathione S-transferase omega 1
|
-2.09115
|
|
BIN3
|
bridging integrator 3
|
-2.05424
|
