| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | penicillin-v-potassium 2.57 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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48 genes differentially expressed following the CRCGN012_HEPG2_24H:I04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPP38 | ribonuclease P/MRP 38kDa subunit | 7.53129 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 6.77762 |
| MOK | MOK protein kinase | 6.45944 |
| CCL2 | chemokine (C-C motif) ligand 2 | 5.89131 |
| SQOR | sulfide quinone oxidoreductase | 5.72681 |
| E2F2 | E2F transcription factor 2 | 5.53292 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.80547 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 3.75874 |
| CBR3 | carbonyl reductase 3 | 3.71063 |
| CSK | c-src tyrosine kinase | 3.41997 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.39363 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.27384 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 3.24181 |
| FZD7 | frizzled class receptor 7 | 2.84648 |
| CYCS | cytochrome c, somatic | 2.79115 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 2.66755 |
| CEP57 | centrosomal protein 57kDa | 2.59918 |
| H2BC12 | H2B clustered histone 12 | 2.59088 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.59037 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.5823 |
| JADE2 | jade family PHD finger 2 | 2.54078 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | 2.51168 |
| KIF14 | kinesin family member 14 | 2.4862 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 2.43009 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 2.4089 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.309 |
| HSPA1A | heat shock 70kDa protein 1A | 2.27457 |
| ATP11B | ATPase, class VI, type 11B | 2.16915 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.00346 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -7.57995 |
| LDHD | lactate dehydrogenase D | -7.52208 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -3.89858 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.80026 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.75774 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.62296 |
| KDM3A | lysine (K)-specific demethylase 3A | -3.49869 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -3.45701 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -3.21143 |
| UBE3C | ubiquitin protein ligase E3C | -3.17175 |
| GNAS | GNAS complex locus | -2.86346 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.76792 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -2.76744 |
| SCAND1 | SCAN domain containing 1 | -2.44991 |
| ZNHIT1 | zinc finger, HIT-type containing 1 | -2.41437 |
| SNX11 | sorting nexin 11 | -2.19653 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -2.16089 |
| PDHX | pyruvate dehydrogenase complex, component X | -2.06774 |
| SPAG4 | sperm associated antigen 4 | -2.0101 |
