| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | sodium 4-((e)-{5-methoxy-4-[(e)-(4-methoxyphenyl)diazenyl]-2-methylphenyl}diazenyl)benzenesulfonate 10.16 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
59 genes differentially expressed following the CRCGN012_HEPG2_24H:I14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 6.23977 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 4.4417 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 4.0274 |
| MSRA | methionine sulfoxide reductase A | 3.84079 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.55901 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 3.20849 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.20756 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.10278 |
| NOTCH1 | notch 1 | 3.10157 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 3.04282 |
| CHN1 | chimerin 1 | 2.99915 |
| ATP11B | ATPase, class VI, type 11B | 2.98981 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 2.98278 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 2.78595 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 2.77256 |
| MCM3 | minichromosome maintenance complex component 3 | 2.71517 |
| NOSIP | nitric oxide synthase interacting protein | 2.58783 |
| EPHA3 | EPH receptor A3 | 2.41739 |
| ABHD6 | abhydrolase domain containing 6 | 2.34882 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 2.34212 |
| TLR4 | toll-like receptor 4 | 2.28072 |
| PIH1D1 | PIH1 domain containing 1 | 2.26049 |
| PRCP | prolylcarboxypeptidase (angiotensinase C) | 2.19599 |
| BLMH | bleomycin hydrolase | 2.18754 |
| KIF20A | kinesin family member 20A | 2.07984 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.06206 |
| CBR3 | carbonyl reductase 3 | 2.04777 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.02407 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -8.07728 |
| ADI1 | acireductone dioxygenase 1 | -5.89379 |
| TLCD3A | TLC domain containing 3A | -4.30071 |
| YME1L1 | YME1-like 1 ATPase | -3.84628 |
| KDM3A | lysine (K)-specific demethylase 3A | -3.81646 |
| TRIB3 | tribbles pseudokinase 3 | -3.79105 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -3.77936 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.74297 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -3.6292 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.61221 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -3.55255 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -3.5135 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.3807 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -3.18273 |
| ZNF586 | zinc finger protein 586 | -3.05917 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.90088 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -2.85341 |
| WASHC4 | WASH complex subunit 4 | -2.84093 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -2.78292 |
| CTSD | cathepsin D | -2.68609 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.53281 |
| FASTKD5 | FAST kinase domains 5 | -2.42791 |
| CDC20 | cell division cycle 20 | -2.37963 |
| HMG20B | high mobility group 20B | -2.27774 |
| MMP23B | matrix metallopeptidase 23B | -2.24063 |
| AMH | anti-Mullerian hormone | -2.17703 |
| SCAND1 | SCAN domain containing 1 | -2.13694 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.12206 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.12077 |
| ABI1 | abl-interactor 1 | -2.09405 |
| GRB7 | growth factor receptor-bound protein 7 | -2.01108 |
