CRCGN012_HEPG2_24H:I18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description sodium 4-((e)-{5-methoxy-4-[(e)-(4-methoxyphenyl)diazenyl]-2-methylphenyl}diazenyl)benzenesulfonate 0.64 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

68 genes differentially expressed following the CRCGN012_HEPG2_24H:I18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
E2F2 E2F transcription factor 2 10.0
CHMP6 charged multivesicular body protein 6 6.22549
ZNF589 zinc finger protein 589 5.74018
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 4.95311
VGLL4 vestigial-like family member 4 4.51277
LYN LYN proto-oncogene, Src family tyrosine kinase 4.21981
UBQLN2 ubiquilin 2 4.05583
IKZF1 IKAROS family zinc finger 1 (Ikaros) 3.99886
CCL2 chemokine (C-C motif) ligand 2 3.76409
STK10 serine/threonine kinase 10 3.59879
ABHD6 abhydrolase domain containing 6 3.57152
ADGRE5 adhesion G protein-coupled receptor E5 3.44981
LOC122526780 uncharacterized LOC122526780 3.17585
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 3.05053
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 2.99568
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2.80328
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.6933
KIF5C kinesin family member 5C 2.68267
GPER1 G protein-coupled estrogen receptor 1 2.66167
AMDHD2 amidohydrolase domain containing 2 2.5868
FPGS folylpolyglutamate synthase 2.51604
WNT3 wingless-type MMTV integration site family, member 3 2.3854
CHEK2 checkpoint kinase 2 2.36435
DIO3 deiodinase, iodothyronine, type III 2.36044
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit 2.32844
YPEL1 yippee-like 1 (Drosophila) 2.30236
RPS27 ribosomal protein S27 2.19496
EPHA3 EPH receptor A3 2.16383
AKAP7 A kinase (PRKA) anchor protein 7 2.1133
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 2.11118
RAB31 RAB31, member RAS oncogene family 2.11107
TEX10 testis expressed 10 2.09232
PUM1 pumilio RNA-binding family member 1 2.08192
SPATA6 spermatogenesis associated 6 2.08174
CA5A carbonic anhydrase VA, mitochondrial 2.08096
MBL2 mannose-binding lectin (protein C) 2, soluble 2.05054
GRWD1 glutamate-rich WD repeat containing 1 2.03269
APOA2 apolipoprotein A-II 2.02136
CHRND cholinergic receptor, nicotinic, delta (muscle) 2.00957
LYRM9 LYR motif containing 9 2.0005

decreased expression

Symbol Name Standardized Value
LDHD lactate dehydrogenase D -7.46921
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -5.84552
FGFR4 fibroblast growth factor receptor 4 -5.65429
NT5DC2 5'-nucleotidase domain containing 2 -5.33722
PCNA proliferating cell nuclear antigen -5.3136
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -4.435
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -4.31187
MEST mesoderm specific transcript -3.9929
LAP3 leucine aminopeptidase 3 -3.47912
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -3.0482
ACAA1 acetyl-CoA acyltransferase 1 -2.93946
VAT1 vesicle amine transport 1 -2.77344
ZNF304 zinc finger protein 304 -2.69933
EPS8L2 EPS8-like 2 -2.69061
GOLT1B golgi transport 1B -2.63317
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.56229
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.522
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.45272
CD58 CD58 molecule -2.3127
CRELD2 cysteine-rich with EGF-like domains 2 -2.27926
ZNF586 zinc finger protein 586 -2.24669
TRAPPC6A trafficking protein particle complex 6A -2.17433
ADI1 acireductone dioxygenase 1 -2.17105
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.14547
SLC35F2 solute carrier family 35, member F2 -2.13812
CCNB2 cyclin B2 -2.13099
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.11675
GRAMD2B GRAM domain containing 2B -2.00022