CRCGN012_HEPG2_24H:I23 Gene Set
Genes
48 genes differentially expressed following the CRCGN012_HEPG2_24H:I23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
E2F2
|
E2F transcription factor 2
|
6.48178
|
|
CSK
|
c-src tyrosine kinase
|
6.13341
|
|
NUCB2
|
nucleobindin 2
|
5.66227
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.76708
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.31943
|
|
CBR3
|
carbonyl reductase 3
|
4.07071
|
|
UBQLN2
|
ubiquilin 2
|
3.9044
|
|
NOTCH1
|
notch 1
|
3.7641
|
|
RPL39L
|
ribosomal protein L39-like
|
2.91484
|
|
TEX10
|
testis expressed 10
|
2.88268
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.85815
|
|
WDR7
|
WD repeat domain 7
|
2.83489
|
|
GATA3
|
GATA binding protein 3
|
2.8033
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.77478
|
|
EVL
|
Enah/Vasp-like
|
2.73543
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.73377
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.70601
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
2.69562
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.64284
|
|
CHN1
|
chimerin 1
|
2.56242
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.52195
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.49719
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
2.4859
|
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
2.41934
|
|
HYOU1
|
hypoxia up-regulated 1
|
2.38384
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.11918
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.02805
|
|
ELAPOR1
|
endosome-lysosome associated apoptosis and autophagy regulator 1
|
2.01495
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-7.07372
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-4.23468
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-4.20136
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.89215
|
|
ZNF586
|
zinc finger protein 586
|
-3.88185
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-3.0825
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.02563
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-2.98514
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-2.97561
|
|
CAB39
|
calcium binding protein 39
|
-2.81652
|
|
SPAG4
|
sperm associated antigen 4
|
-2.62835
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-2.56867
|
|
HMG20B
|
high mobility group 20B
|
-2.54612
|
|
NFKBIA
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
|
-2.3901
|
|
ABCF3
|
ATP-binding cassette, sub-family F (GCN20), member 3
|
-2.3898
|
|
NUP93
|
nucleoporin 93kDa
|
-2.19383
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.18272
|
|
FAM174C
|
family with sequence similarity 174 member C
|
-2.08364
|
|
RNF167
|
ring finger protein 167
|
-2.06577
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
-2.05109
|
