CRCGN012_HEPG2_24H:I24 Gene Set
Genes
46 genes differentially expressed following the CRCGN012_HEPG2_24H:I24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
6.71647
|
|
RPL39L
|
ribosomal protein L39-like
|
6.32375
|
|
STIMATE
|
STIM activating enhancer
|
5.7
|
|
NUCB2
|
nucleobindin 2
|
5.4264
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.49109
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.28164
|
|
NOTCH1
|
notch 1
|
3.17004
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.03455
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
2.96948
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.83177
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.82949
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
2.81428
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
2.68371
|
|
AKT1
|
v-akt murine thymoma viral oncogene homolog 1
|
2.58392
|
|
FCHO1
|
FCH domain only 1
|
2.56213
|
|
SLC35B1
|
solute carrier family 35, member B1
|
2.3409
|
|
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha
|
2.33924
|
|
ADH5
|
alcohol dehydrogenase 5 (class III), chi polypeptide
|
2.33567
|
|
SQOR
|
sulfide quinone oxidoreductase
|
2.28282
|
|
RNPS1
|
RNA binding protein S1, serine-rich domain
|
2.1572
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.06175
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.0215
|
|
SLC2A6
|
solute carrier family 2 (facilitated glucose transporter), member 6
|
2.00298
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-6.24888
|
|
ADI1
|
acireductone dioxygenase 1
|
-6.1407
|
|
CD320
|
CD320 molecule
|
-6.05831
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-4.03323
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.40199
|
|
TUBB6
|
tubulin, beta 6 class V
|
-3.34645
|
|
FASTKD5
|
FAST kinase domains 5
|
-3.05967
|
|
VAT1
|
vesicle amine transport 1
|
-2.88921
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.87349
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.85702
|
|
CDC42
|
cell division cycle 42
|
-2.68952
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-2.64903
|
|
CCNB2
|
cyclin B2
|
-2.60029
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.56882
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.55706
|
|
GNAS
|
GNAS complex locus
|
-2.44131
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.26747
|
|
KIFC1
|
kinesin family member C1
|
-2.17792
|
|
G3BP1
|
GTPase activating protein (SH3 domain) binding protein 1
|
-2.08293
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.04303
|
|
CTSL
|
cathepsin L
|
-2.04248
|
|
BTNL2
|
butyrophilin-like 2
|
-2.03727
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.00942
|
