CRCGN012_HEPG2_24H:J08 Gene Set
Genes
54 genes differentially expressed following the CRCGN012_HEPG2_24H:J08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
5.18606
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.85653
|
|
CBR3
|
carbonyl reductase 3
|
4.14864
|
|
CCNA1
|
cyclin A1
|
3.48962
|
|
CHN1
|
chimerin 1
|
3.46116
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
3.38652
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.23344
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.2096
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
3.16963
|
|
NENF
|
neudesin neurotrophic factor
|
2.70377
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.69947
|
|
DRAP1
|
DR1-associated protein 1 (negative cofactor 2 alpha)
|
2.68301
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.58928
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.45073
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.44409
|
|
LCN2
|
lipocalin 2
|
2.43033
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.42232
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.35521
|
|
PIH1D1
|
PIH1 domain containing 1
|
2.34282
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
2.31306
|
|
TAC4
|
tachykinin 4 (hemokinin)
|
2.30849
|
|
CSK
|
c-src tyrosine kinase
|
2.28533
|
|
TBP
|
TATA box binding protein
|
2.2459
|
|
PRR15L
|
proline rich 15-like
|
2.23977
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.23544
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.11961
|
|
PEF1
|
penta-EF-hand domain containing 1
|
2.07396
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
2.07388
|
|
UBQLN2
|
ubiquilin 2
|
2.04566
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-7.31334
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-6.17885
|
|
TUBB6
|
tubulin, beta 6 class V
|
-5.09485
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.85349
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-4.84015
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.70625
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.25463
|
|
TSEN2
|
TSEN2 tRNA splicing endonuclease subunit
|
-4.18852
|
|
ID2
|
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
|
-4.04579
|
|
DPH2
|
DPH2 homolog (S. cerevisiae)
|
-3.71072
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.66627
|
|
GNAS
|
GNAS complex locus
|
-3.51185
|
|
RBM15B
|
RNA binding motif protein 15B
|
-3.12901
|
|
DNM1L
|
dynamin 1-like
|
-2.94804
|
|
ZNF586
|
zinc finger protein 586
|
-2.93973
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-2.8648
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.62206
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.45275
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.28664
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.26501
|
|
TOR1A
|
torsin family 1, member A (torsin A)
|
-2.25119
|
|
LDHD
|
lactate dehydrogenase D
|
-2.20763
|
|
PEG10
|
paternally expressed 10
|
-2.14835
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-2.13724
|
|
ABCF3
|
ATP-binding cassette, sub-family F (GCN20), member 3
|
-2.12951
|
