CRCGN012_HEPG2_24H:J09 Gene Set
Genes
47 genes differentially expressed following the CRCGN012_HEPG2_24H:J09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.98977
|
|
MAMLD1
|
mastermind-like domain containing 1
|
4.11201
|
|
LCN2
|
lipocalin 2
|
3.91096
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.82109
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
3.67997
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
3.39803
|
|
GPATCH8
|
G patch domain containing 8
|
3.15276
|
|
LAGE3
|
L antigen family, member 3
|
3.12328
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.04955
|
|
CSK
|
c-src tyrosine kinase
|
2.96261
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.9377
|
|
MYLK
|
myosin light chain kinase
|
2.80049
|
|
EPHA3
|
EPH receptor A3
|
2.50402
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.49003
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.46362
|
|
CYCS
|
cytochrome c, somatic
|
2.4166
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.41304
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
2.34758
|
|
ZKSCAN7
|
zinc finger with KRAB and SCAN domains 7
|
2.27541
|
|
MYBL2
|
v-myb avian myeloblastosis viral oncogene homolog-like 2
|
2.17102
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
2.14377
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.06631
|
|
PTPN1
|
protein tyrosine phosphatase, non-receptor type 1
|
2.04716
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-6.20493
|
|
DNM1L
|
dynamin 1-like
|
-5.55653
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-5.53544
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.03471
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.82734
|
|
ENOPH1
|
enolase-phosphatase 1
|
-3.65538
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.53125
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-3.33849
|
|
MAP7
|
microtubule-associated protein 7
|
-3.29045
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-3.25064
|
|
TNFRSF21
|
tumor necrosis factor receptor superfamily, member 21
|
-3.03448
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-2.99325
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
-2.95126
|
|
GDF15
|
growth differentiation factor 15
|
-2.8754
|
|
GOLT1B
|
golgi transport 1B
|
-2.84633
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.66145
|
|
PDHX
|
pyruvate dehydrogenase complex, component X
|
-2.49928
|
|
RBM15B
|
RNA binding motif protein 15B
|
-2.3466
|
|
TXNRD1
|
thioredoxin reductase 1
|
-2.23085
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.17091
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.11629
|
|
H2AB2
|
H2A.B variant histone 2
|
-2.10694
|
|
SCAND1
|
SCAN domain containing 1
|
-2.05791
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.00012
|
