CRCGN012_HEPG2_24H:J11 Gene Set
Genes
46 genes differentially expressed following the CRCGN012_HEPG2_24H:J11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
8.50951
|
|
CSK
|
c-src tyrosine kinase
|
8.3723
|
|
E2F2
|
E2F transcription factor 2
|
5.74722
|
|
SQOR
|
sulfide quinone oxidoreductase
|
5.03094
|
|
JADE2
|
jade family PHD finger 2
|
4.82563
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.48424
|
|
STK10
|
serine/threonine kinase 10
|
3.93382
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.92157
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.86026
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.82532
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
3.26581
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.76009
|
|
GATA3
|
GATA binding protein 3
|
2.59429
|
|
DRAP1
|
DR1-associated protein 1 (negative cofactor 2 alpha)
|
2.52982
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.38342
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.37397
|
|
LCN2
|
lipocalin 2
|
2.37295
|
|
VGLL4
|
vestigial-like family member 4
|
2.3379
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.18592
|
|
MMAB
|
methylmalonic aciduria (cobalamin deficiency) cblB type
|
2.02274
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TRIB3
|
tribbles pseudokinase 3
|
-8.25441
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.45668
|
|
LDHD
|
lactate dehydrogenase D
|
-4.23271
|
|
DSG2
|
desmoglein 2
|
-4.17416
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-4.09541
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.04622
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-4.04107
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.02247
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.80158
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.44365
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-3.34894
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.23874
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.21844
|
|
RGS2
|
regulator of G-protein signaling 2
|
-3.05909
|
|
YME1L1
|
YME1-like 1 ATPase
|
-3.03039
|
|
GDF15
|
growth differentiation factor 15
|
-2.82932
|
|
NVL
|
nuclear VCP-like
|
-2.81437
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.51645
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.47668
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.43754
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.37993
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-2.29891
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
-2.21975
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
-2.20635
|
|
STMN1
|
stathmin 1
|
-2.19839
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-2.05117
|
