CRCGN012_HEPG2_24H:J12 Gene Set
Genes
47 genes differentially expressed following the CRCGN012_HEPG2_24H:J12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
E2F2
|
E2F transcription factor 2
|
8.01866
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
6.51858
|
|
CYCS
|
cytochrome c, somatic
|
5.72191
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.67739
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.95636
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
4.8961
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
4.15542
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.99734
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.90747
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
3.82276
|
|
EPHB2
|
EPH receptor B2
|
3.74681
|
|
LCN2
|
lipocalin 2
|
3.70487
|
|
CSK
|
c-src tyrosine kinase
|
3.52377
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
3.30797
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
3.12511
|
|
SMIM40
|
small integral membrane protein 40
|
3.08363
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.68467
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.38619
|
|
ASIC1
|
acid sensing (proton gated) ion channel 1
|
2.37202
|
|
FBXO17
|
F-box protein 17
|
2.28393
|
|
ARMCX2
|
armadillo repeat containing, X-linked 2
|
2.27101
|
|
BAMBI
|
BMP and activin membrane-bound inhibitor
|
2.19626
|
|
GPR162
|
G protein-coupled receptor 162
|
2.19445
|
|
NNAT
|
neuronatin
|
2.12041
|
|
ZNF589
|
zinc finger protein 589
|
2.05432
|
|
CTR9
|
CTR9, Paf1/RNA polymerase II complex component
|
2.02186
|
|
RBMS3
|
RNA binding motif, single stranded interacting protein 3
|
2.00601
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-8.13436
|
|
CD320
|
CD320 molecule
|
-5.05896
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.4959
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.2489
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-4.08377
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.04426
|
|
FBXO7
|
F-box protein 7
|
-3.66541
|
|
ZNF586
|
zinc finger protein 586
|
-3.62674
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.78614
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-2.77256
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-2.58921
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.47098
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.40947
|
|
RNF167
|
ring finger protein 167
|
-2.33665
|
|
S100A9
|
S100 calcium binding protein A9
|
-2.24398
|
|
GNG10
|
guanine nucleotide binding protein (G protein), gamma 10
|
-2.12198
|
|
RAPGEF6
|
Rap guanine nucleotide exchange factor (GEF) 6
|
-2.09392
|
|
MGRN1
|
mahogunin ring finger 1, E3 ubiquitin protein ligase
|
-2.09162
|
|
RGPD2
|
RANBP2-like and GRIP domain containing 2
|
-2.091
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.0347
|
