| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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70 genes differentially expressed following the CRCGN012_HEPG2_24H:J13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 7.87836 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 6.89601 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 5.34589 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 4.89755 |
| ATP11B | ATPase, class VI, type 11B | 4.80398 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 4.6835 |
| RAB21 | RAB21, member RAS oncogene family | 4.44611 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 3.73522 |
| CHMP6 | charged multivesicular body protein 6 | 3.72157 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 3.70658 |
| VGLL4 | vestigial-like family member 4 | 3.36856 |
| TBC1D10C | TBC1 domain family, member 10C | 3.2782 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 3.1643 |
| KLHL9 | kelch-like family member 9 | 3.15303 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 3.04849 |
| EVL | Enah/Vasp-like | 3.021 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.00953 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 2.95126 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.91189 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 2.81285 |
| LOC128031832 | uncharacterized LOC128031832 | 2.44302 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.42593 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.42022 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 2.39294 |
| CEP57 | centrosomal protein 57kDa | 2.32137 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 2.15662 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 | 2.11519 |
| C1RL | complement component 1, r subcomponent-like | 2.10148 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 2.09306 |
| RPP30 | ribonuclease P/MRP 30kDa subunit | 2.05926 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | 2.04704 |
| MRPL42 | mitochondrial ribosomal protein L42 | 2.04014 |
| PCDHB11 | protocadherin beta 11 | 2.01782 |
| CCNF | cyclin F | 2.00075 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -7.80178 |
| ADI1 | acireductone dioxygenase 1 | -6.90397 |
| CDC20 | cell division cycle 20 | -6.88968 |
| CD58 | CD58 molecule | -6.16029 |
| CCNB2 | cyclin B2 | -5.73673 |
| TP53BP2 | tumor protein p53 binding protein 2 | -5.47262 |
| THAP11 | THAP domain containing 11 | -5.20752 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -5.17817 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.92796 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.86152 |
| CHMP4B | charged multivesicular body protein 4B | -4.76558 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -4.56682 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | -4.37997 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.12647 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.90916 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -3.58198 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.31931 |
| SPAG4 | sperm associated antigen 4 | -3.29591 |
| CTSD | cathepsin D | -3.22078 |
| TRIB3 | tribbles pseudokinase 3 | -3.21991 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -3.11261 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -3.01548 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.99033 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.83054 |
| TENT4A | terminal nucleotidyltransferase 4A | -2.82165 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -2.67372 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -2.60774 |
| RAB38 | RAB38, member RAS oncogene family | -2.4622 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.30452 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -2.29635 |
| SNX11 | sorting nexin 11 | -2.21793 |
| WDR47 | WD repeat domain 47 | -2.20916 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.19987 |
| REEP5 | receptor accessory protein 5 | -2.12623 |
| FADS2 | fatty acid desaturase 2 | -2.11581 |
| PCNA | proliferating cell nuclear antigen | -2.08017 |
