CRCGN012_HEPG2_24H:J14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

51 genes differentially expressed following the CRCGN012_HEPG2_24H:J14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 6.96392
CBR3 carbonyl reductase 3 6.20111
PEX11A peroxisomal biogenesis factor 11 alpha 5.64866
GPATCH8 G patch domain containing 8 5.60495
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 5.50079
PLSCR1 phospholipid scramblase 1 4.98348
UBQLN2 ubiquilin 2 4.31549
CIAO3 cytosolic iron-sulfur assembly component 3 3.86051
DYNLT3 dynein, light chain, Tctex-type 3 3.72337
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 3.68847
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 3.44539
BZW2 basic leucine zipper and W2 domains 2 3.31119
PPARG peroxisome proliferator-activated receptor gamma 3.19207
E2F2 E2F transcription factor 2 2.97988
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 2.97469
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.92754
C2CD2 C2 calcium-dependent domain containing 2 2.82225
CYCS cytochrome c, somatic 2.80543
RPL39L ribosomal protein L39-like 2.61321
NOTCH1 notch 1 2.54818
H2BC12 H2B clustered histone 12 2.47126
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.4113
IDE insulin-degrading enzyme 2.39797
TBC1D31 TBC1 domain family, member 31 2.35165
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 2.34407
GATA3 GATA binding protein 3 2.30915
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae) 2.28158
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 2.10233
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 2.07631
CXCL12 chemokine (C-X-C motif) ligand 12 2.05841
CALML5 calmodulin-like 5 2.04602
LPAR2 lysophosphatidic acid receptor 2 2.00456

decreased expression

Symbol Name Standardized Value
CCNB2 cyclin B2 -7.15734
MRPS2 mitochondrial ribosomal protein S2 -4.48506
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -3.60316
FGFR4 fibroblast growth factor receptor 4 -3.28919
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -3.14944
NT5DC2 5'-nucleotidase domain containing 2 -3.13008
RPS4Y1 ribosomal protein S4, Y-linked 1 -3.03782
NGRN neugrin, neurite outgrowth associated -2.9826
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.97535
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.82756
PECR peroxisomal trans-2-enoyl-CoA reductase -2.78646
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.75883
LDHD lactate dehydrogenase D -2.67004
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.53133
ADI1 acireductone dioxygenase 1 -2.48094
PHKG2 phosphorylase kinase, gamma 2 (testis) -2.26981
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) -2.22126
GNAS GNAS complex locus -2.12749
POLM polymerase (DNA directed), mu -2.03684