CRCGN012_HEPG2_24H:J15 Gene Set
Genes
46 genes differentially expressed following the CRCGN012_HEPG2_24H:J15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.54305
|
|
MAMLD1
|
mastermind-like domain containing 1
|
5.3013
|
|
UBQLN2
|
ubiquilin 2
|
4.9918
|
|
VGLL4
|
vestigial-like family member 4
|
4.93497
|
|
LCN2
|
lipocalin 2
|
4.86916
|
|
GPATCH8
|
G patch domain containing 8
|
4.0941
|
|
EVL
|
Enah/Vasp-like
|
3.66746
|
|
FCHO1
|
FCH domain only 1
|
3.65935
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.68356
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
2.64232
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
2.61316
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.57085
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.45178
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.37656
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.28214
|
|
PLS1
|
plastin 1
|
2.27597
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.23711
|
|
TBP
|
TATA box binding protein
|
2.22765
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.1624
|
|
MYLK
|
myosin light chain kinase
|
2.13131
|
|
MELK
|
maternal embryonic leucine zipper kinase
|
2.09953
|
|
PFKL
|
phosphofructokinase, liver
|
2.00884
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-6.26486
|
|
CCNB1
|
cyclin B1
|
-5.63815
|
|
TUBB6
|
tubulin, beta 6 class V
|
-5.2668
|
|
LDHD
|
lactate dehydrogenase D
|
-4.97629
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.87137
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.85576
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-4.74503
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.39153
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.8852
|
|
WASHC4
|
WASH complex subunit 4
|
-3.65062
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
-3.13271
|
|
CCNB2
|
cyclin B2
|
-2.98128
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-2.86045
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.78699
|
|
LAP3
|
leucine aminopeptidase 3
|
-2.68374
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.6743
|
|
LRRC41
|
leucine rich repeat containing 41
|
-2.58655
|
|
MACF1
|
microtubule-actin crosslinking factor 1
|
-2.41162
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.35942
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.28979
|
|
USP6NL
|
USP6 N-terminal like
|
-2.26856
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.17335
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
-2.10785
|
|
ZW10
|
zw10 kinetochore protein
|
-2.07586
|
