CRCGN012_HEPG2_24H:J16 Gene Set
Genes
51 genes differentially expressed following the CRCGN012_HEPG2_24H:J16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
E2F2
|
E2F transcription factor 2
|
5.87943
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.97896
|
|
STIMATE
|
STIM activating enhancer
|
3.67724
|
|
LCN2
|
lipocalin 2
|
3.54958
|
|
SATB1
|
SATB homeobox 1
|
3.37189
|
|
STK10
|
serine/threonine kinase 10
|
3.31153
|
|
EPHB2
|
EPH receptor B2
|
3.22515
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.18556
|
|
UBQLN2
|
ubiquilin 2
|
3.0885
|
|
DNAJB2
|
DnaJ (Hsp40) homolog, subfamily B, member 2
|
3.0621
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
2.91143
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.83893
|
|
CSK
|
c-src tyrosine kinase
|
2.76493
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.69257
|
|
NOTCH1
|
notch 1
|
2.68909
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
2.68331
|
|
CCNH
|
cyclin H
|
2.66329
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.63919
|
|
HOXA10
|
homeobox A10
|
2.61563
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.49496
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
2.44237
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.41525
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
2.2967
|
|
CEP57
|
centrosomal protein 57kDa
|
2.16473
|
|
TPD52L2
|
tumor protein D52-like 2
|
2.13625
|
|
PRKCQ
|
protein kinase C, theta
|
2.08426
|
|
CASP10
|
caspase 10, apoptosis-related cysteine peptidase
|
2.02619
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLCD3A
|
TLC domain containing 3A
|
-4.76861
|
|
MAP7
|
microtubule-associated protein 7
|
-4.41287
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.43385
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.32817
|
|
ZNF586
|
zinc finger protein 586
|
-3.31719
|
|
FASTKD5
|
FAST kinase domains 5
|
-3.28256
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.20874
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.20686
|
|
VAT1
|
vesicle amine transport 1
|
-3.11415
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-2.9424
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.8841
|
|
CD58
|
CD58 molecule
|
-2.72184
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.66463
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.6332
|
|
MTFR1
|
mitochondrial fission regulator 1
|
-2.60701
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.5867
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-2.53146
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.42349
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.26046
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.22254
|
|
XPO7
|
exportin 7
|
-2.07664
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.06984
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.06428
|
|
LSG1
|
large 60S subunit nuclear export GTPase 1
|
-2.00141
|
