| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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47 genes differentially expressed following the CRCGN012_HEPG2_24H:J17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYLK | myosin light chain kinase | 8.60853 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 5.79787 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.92048 |
| RPL39L | ribosomal protein L39-like | 4.18653 |
| PNKP | polynucleotide kinase 3'-phosphatase | 4.04607 |
| NOTCH1 | notch 1 | 3.85049 |
| CSK | c-src tyrosine kinase | 3.83725 |
| STK10 | serine/threonine kinase 10 | 3.73969 |
| CHMP6 | charged multivesicular body protein 6 | 3.7118 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.27229 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.25917 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.11443 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 2.89702 |
| ZNF589 | zinc finger protein 589 | 2.78288 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 2.67182 |
| KLHL9 | kelch-like family member 9 | 2.59335 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.53244 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.53116 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.49407 |
| TLR4 | toll-like receptor 4 | 2.40139 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.35523 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 2.32992 |
| PFKL | phosphofructokinase, liver | 2.18077 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.09833 |
| IFT46 | intraflagellar transport 46 | 2.06713 |
| UBQLN2 | ubiquilin 2 | 2.0589 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) | 2.05444 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 2.05243 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -7.23897 |
| SLC35F2 | solute carrier family 35, member F2 | -6.20357 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.33538 |
| MAPK13 | mitogen-activated protein kinase 13 | -4.27932 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -4.18182 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -4.15652 |
| MRPS16 | mitochondrial ribosomal protein S16 | -4.12499 |
| TUBB6 | tubulin, beta 6 class V | -4.11598 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -3.90433 |
| MAP7 | microtubule-associated protein 7 | -3.80784 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -3.23139 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.96232 |
| SSBP2 | single-stranded DNA binding protein 2 | -2.65012 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.6039 |
| HMG20B | high mobility group 20B | -2.60276 |
| SEC24C | SEC24 family member C | -2.52286 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -2.49644 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.10224 |
| BOLA1 | bolA family member 1 | -2.08183 |
