CRCGN012_HEPG2_24H:J18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

63 genes differentially expressed following the CRCGN012_HEPG2_24H:J18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 8.08314
RPL39L ribosomal protein L39-like 7.82097
E2F2 E2F transcription factor 2 6.81084
PNKP polynucleotide kinase 3'-phosphatase 5.14264
CCL2 chemokine (C-C motif) ligand 2 5.10354
UBQLN2 ubiquilin 2 4.97987
TAC4 tachykinin 4 (hemokinin) 4.86318
MAMLD1 mastermind-like domain containing 1 4.76958
CSK c-src tyrosine kinase 4.53278
TIAM1 T-cell lymphoma invasion and metastasis 1 4.42484
CASP2 caspase 2, apoptosis-related cysteine peptidase 4.25813
CBR1 carbonyl reductase 1 3.8424
NOSIP nitric oxide synthase interacting protein 3.63651
RXYLT1 ribitol xylosyltransferase 1 3.14797
GARRE1 granule associated Rac and RHOG effector 1 2.94414
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.82635
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.71764
SNX17 sorting nexin 17 2.59466
CYCS cytochrome c, somatic 2.52532
RECK reversion-inducing-cysteine-rich protein with kazal motifs 2.49898
ADGRE5 adhesion G protein-coupled receptor E5 2.45178
SCRN1 secernin 1 2.41439
GCH1 GTP cyclohydrolase 1 2.26472
RRAGA Ras-related GTP binding A 2.12596
CEPT1 choline/ethanolamine phosphotransferase 1 2.10158
ADA2 adenosine deaminase 2 2.08769
DIPK1A divergent protein kinase domain 1A 2.06366

decreased expression

Symbol Name Standardized Value
GDF15 growth differentiation factor 15 -6.05766
GNAS GNAS complex locus -5.34456
CCDC86 coiled-coil domain containing 86 -5.09611
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -4.96351
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -4.94695
FASTKD5 FAST kinase domains 5 -4.8729
LDHD lactate dehydrogenase D -4.86475
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -4.70152
SLC35F2 solute carrier family 35, member F2 -4.03273
CCNB2 cyclin B2 -3.69335
UGDH UDP-glucose 6-dehydrogenase -3.65882
TBCB tubulin folding cofactor B -3.59894
PCNA proliferating cell nuclear antigen -3.38875
RGS2 regulator of G-protein signaling 2 -3.16697
THAP11 THAP domain containing 11 -2.82455
ARID5B AT rich interactive domain 5B (MRF1-like) -2.62971
IPO13 importin 13 -2.62921
FABP5 fatty acid binding protein 5 (psoriasis-associated) -2.4211
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -2.38972
ZNF146 zinc finger protein 146 -2.36549
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -2.3062
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -2.28355
LIN37 lin-37 DREAM MuvB core complex component -2.27963
FBRS fibrosin -2.24164
CAPNS1 calpain, small subunit 1 -2.23489
RBM42 RNA binding motif protein 42 -2.22514
CANT1 calcium activated nucleotidase 1 -2.1919
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 -2.16422
HSPB6 heat shock protein, alpha-crystallin-related, B6 -2.13995
RNF40 ring finger protein 40, E3 ubiquitin protein ligase -2.11021
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) -2.06496
ADRM1 adhesion regulating molecule 1 -2.04618
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -2.04144
RPRD2 regulation of nuclear pre-mRNA domain containing 2 -2.02639
THYN1 thymocyte nuclear protein 1 -2.01838
LRFN3 leucine rich repeat and fibronectin type III domain containing 3 -2.00984