CRCGN012_HEPG2_24H:J21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description ethyl 2-{(3z)-6-(ethylamino)-3-[(z)-ethylimino]-2,7-dimethyl-3h-xanthen-9-yl}benzoate hydrochloride 5.11 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

1006 genes differentially expressed following the CRCGN012_HEPG2_24H:J21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 10.0
INPP1 inositol polyphosphate-1-phosphatase 9.64149
TXNRD1 thioredoxin reductase 1 9.22812
FOSL1 FOS-like antigen 1 8.06845
TIMP2 TIMP metallopeptidase inhibitor 2 7.98273
IGFBP3 insulin-like growth factor binding protein 3 7.31252
TRIB3 tribbles pseudokinase 3 7.12713
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 7.0347
LRP10 low density lipoprotein receptor-related protein 10 7.01053
LCN2 lipocalin 2 6.94507
SQSTM1 sequestosome 1 6.69305
E2F2 E2F transcription factor 2 6.6459
ABHD4 abhydrolase domain containing 4 6.59217
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 6.47167
ZFP36 ZFP36 ring finger protein 6.40194
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 6.32287
MVP major vault protein 6.13608
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 5.99155
DDIT4 DNA-damage-inducible transcript 4 5.88002
CNPY3 canopy FGF signaling regulator 3 5.82601
CHMP6 charged multivesicular body protein 6 5.61071
IL4R interleukin 4 receptor 5.56322
SHB Src homology 2 domain containing adaptor protein B 5.56073
KLHL21 kelch-like family member 21 5.45742
MICALL1 MICAL-like 1 5.30899
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 5.30707
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 5.22915
VAT1 vesicle amine transport 1 5.21417
GFOD1 glucose-fructose oxidoreductase domain containing 1 5.09327
GFPT1 glutamine--fructose-6-phosphate transaminase 1 5.02528
AARS1 alanyl-tRNA synthetase 1 5.00705
EGR1 early growth response 1 4.86663
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 4.86173
STX1A syntaxin 1A (brain) 4.7619
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 4.74856
ASCC3 activating signal cointegrator 1 complex subunit 3 4.68003
KIFBP kinesin family binding protein 4.62774
BZW2 basic leucine zipper and W2 domains 2 4.56556
SLC35F2 solute carrier family 35, member F2 4.49404
PTPN12 protein tyrosine phosphatase, non-receptor type 12 4.44958
ADO 2-aminoethanethiol (cysteamine) dioxygenase 4.37781
MYC v-myc avian myelocytomatosis viral oncogene homolog 4.37331
CCDC92 coiled-coil domain containing 92 4.31526
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 4.31018
CAMTA2 calmodulin binding transcription activator 2 4.30239
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 4.26519
CAB39 calcium binding protein 39 4.26453
IER3 immediate early response 3 4.17225
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 4.07826
DSG2 desmoglein 2 4.07652
ANO1 anoctamin 1, calcium activated chloride channel 4.07618
PRAF2 PRA1 domain family, member 2 4.01547
ADGRE5 adhesion G protein-coupled receptor E5 4.01297
ATF6 activating transcription factor 6 3.97014
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 3.87659
CIAO3 cytosolic iron-sulfur assembly component 3 3.82537
TRIM13 tripartite motif containing 13 3.81641
TRIB1 tribbles pseudokinase 1 3.81596
ACOT9 acyl-CoA thioesterase 9 3.78705
ADRB2 adrenoceptor beta 2, surface 3.74496
TES testin LIM domain protein 3.73237
LOC128125814 uncharacterized LOC128125814 3.70522
NANOS3 nanos homolog 3 (Drosophila) 3.65171
UGDH UDP-glucose 6-dehydrogenase 3.64367
SMIM40 small integral membrane protein 40 3.62696
BYSL bystin-like 3.6243
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 3.57191
YIPF3 Yip1 domain family, member 3 3.54261
SQOR sulfide quinone oxidoreductase 3.53674
IL37 interleukin 37 3.52627
TERF2IP telomeric repeat binding factor 2, interacting protein 3.51178
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 3.49629
CASC3 cancer susceptibility candidate 3 3.44111
ZFP69B ZFP69 zinc finger protein B 3.42767
FOXO4 forkhead box O4 3.38752
TOMM34 translocase of outer mitochondrial membrane 34 3.38731
YARS1 tyrosyl-tRNA synthetase 1 3.34701
GTPBP2 GTP binding protein 2 3.32315
ZYX zyxin 3.31397
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 3.30001
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 3.2964
PPARD peroxisome proliferator-activated receptor delta 3.29548
SARS1 seryl-tRNA synthetase 1 3.24348
GARS1 glycyl-tRNA synthetase 1 3.23568
NPDC1 neural proliferation, differentiation and control, 1 3.22392
EPN2 epsin 2 3.20191
FPGS folylpolyglutamate synthase 3.19664
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3.18852
TBPL1 TBP-like 1 3.17849
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 3.17472
BICRAL BICRA like chromatin remodeling complex associated protein 3.15608
NABP1 nucleic acid binding protein 1 3.15592
STAT4 signal transducer and activator of transcription 4 3.14831
SRC SRC proto-oncogene, non-receptor tyrosine kinase 3.14659
MAMLD1 mastermind-like domain containing 1 3.14544
H2BC21 H2B clustered histone 21 3.13515
PHKA1 phosphorylase kinase, alpha 1 (muscle) 3.11598
DPP4 dipeptidyl-peptidase 4 3.11513
IKZF1 IKAROS family zinc finger 1 (Ikaros) 3.10627
ATOSB atos homolog B 3.10045
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.093
P2RY10 purinergic receptor P2Y, G-protein coupled, 10 3.08782
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 3.0755
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 3.06527
PXDC1 PX domain containing 1 3.0506
UPP1 uridine phosphorylase 1 3.03724
PDGFA platelet-derived growth factor alpha polypeptide 3.01457
TFE3 transcription factor binding to IGHM enhancer 3 3.00623
SYNGR3 synaptogyrin 3 2.99788
TP53BP2 tumor protein p53 binding protein 2 2.99647
UFM1 ubiquitin-fold modifier 1 2.99441
PRKCQ protein kinase C, theta 2.98558
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 2.98527
NIBAN1 niban apoptosis regulator 1 2.97063
SLC35F6 solute carrier family 35, member F6 2.95706
NPC1 Niemann-Pick disease, type C1 2.9459
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 2.94467
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 2.94463
GALR1 galanin receptor 1 2.92672
LCOR ligand dependent nuclear receptor corepressor 2.90961
RAP1GAP RAP1 GTPase activating protein 2.90418
CDK7 cyclin-dependent kinase 7 2.90297
RTCA RNA 3'-terminal phosphate cyclase 2.89438
SNX6 sorting nexin 6 2.89057
ARHGAP22 Rho GTPase activating protein 22 2.88216
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.88055
PSPC1 paraspeckle component 1 2.8725
GNLY granulysin 2.86169
FBXO7 F-box protein 7 2.85957
ALAS1 5'-aminolevulinate synthase 1 2.85678
SOCS2 suppressor of cytokine signaling 2 2.85615
LIF leukemia inhibitory factor 2.83496
ZNF225 zinc finger protein 225 2.83301
NARS1 asparaginyl-tRNA synthetase 1 2.82919
MYH9 myosin, heavy chain 9, non-muscle 2.8268
NR1H2 nuclear receptor subfamily 1, group H, member 2 2.82429
PARP8 poly (ADP-ribose) polymerase family, member 8 2.82034
ASNS asparagine synthetase (glutamine-hydrolyzing) 2.80979
GID4 GID complex subunit 4 2.80463
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.80234
HKDC1 hexokinase domain containing 1 2.80006
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 2.79921
OPTN optineurin 2.79852
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.79841
KLRC4-KLRK1 KLRC4-KLRK1 readthrough 2.78944
PKN1 protein kinase N1 2.78714
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 2.77869
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 2.77528
SH3GLB1 SH3-domain GRB2-like endophilin B1 2.77315
XPOT exportin, tRNA 2.76972
STEEP1 STING1 ER exit protein 1 2.7667
CASS4 Cas scaffolding protein family member 4 2.75616
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 2.75539
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 2.74913
JOSD1 Josephin domain containing 1 2.74578
EXOC6B exocyst complex component 6B 2.74223
FASLG Fas ligand (TNF superfamily, member 6) 2.73943
ZBTB35 zinc finger and BTB domain containing 35 2.73894
FHL2 four and a half LIM domains 2 2.73701
PHLDA2 pleckstrin homology-like domain, family A, member 2 2.73186
EGFR epidermal growth factor receptor 2.72604
PYGB phosphorylase, glycogen; brain 2.72491
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 2.72338
TARS1 threonyl-tRNA synthetase 1 2.70459
TESK1 testis-specific kinase 1 2.70057
TAS2R10 taste receptor, type 2, member 10 2.6977
TGFB1I1 transforming growth factor beta 1 induced transcript 1 2.69715
TMEM156 transmembrane protein 156 2.69609
VSIG2 V-set and immunoglobulin domain containing 2 2.68401
RIN1 Ras and Rab interactor 1 2.68028
MOSPD1 motile sperm domain containing 1 2.6794
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa 2.67856
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.67598
CCDC68 coiled-coil domain containing 68 2.67458
GRB10 growth factor receptor-bound protein 10 2.67424
CA6 carbonic anhydrase VI 2.67312
CYSLTR1 cysteinyl leukotriene receptor 1 2.67162
BPGM 2,3-bisphosphoglycerate mutase 2.64078
ULK1 unc-51 like autophagy activating kinase 1 2.63747
MYH4 myosin, heavy chain 4, skeletal muscle 2.63688
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 2.63348
DRD1 dopamine receptor D1 2.63036
OSGIN2 oxidative stress induced growth inhibitor family member 2 2.6296
CSNK1E casein kinase 1, epsilon 2.62147
ATF4 activating transcription factor 4 2.61798
SIRT2 sirtuin 2 2.61443
IPO13 importin 13 2.60871
IFNW1 interferon, omega 1 2.60104
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 2.5982
JUN jun proto-oncogene 2.59416
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 2.59069
MPC2 mitochondrial pyruvate carrier 2 2.58734
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2.58721
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 2.58566
C6ORF89 chromosome 6 open reading frame 89 2.5856
RAB3B RAB3B, member RAS oncogene family 2.57777
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 2.55953
DUSP3 dual specificity phosphatase 3 2.55881
MAP1S microtubule-associated protein 1S 2.55872
GLRX glutaredoxin (thioltransferase) 2.55816
NT5E 5'-nucleotidase, ecto (CD73) 2.55812
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 2.55691
ZMYM5 zinc finger, MYM-type 5 2.55253
ZNF79 zinc finger protein 79 2.5524
VAC14 Vac14 homolog (S. cerevisiae) 2.55102
SNAI1 snail family zinc finger 1 2.54998
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 2.54653
H2BC17 H2B clustered histone 17 2.54599
HABP4 hyaluronan binding protein 4 2.54421
KLRC4 killer cell lectin-like receptor subfamily C, member 4 2.54227
C2CD2L C2CD2-like 2.53797
MEAK7 MTOR associated protein, eak-7 homolog 2.53471
DCAF4 DDB1 and CUL4 associated factor 4 2.52968
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 2.5275
PHF20L1 PHD finger protein 20-like 1 2.52644
TM4SF20 transmembrane 4 L six family member 20 2.5236
RBM41 RNA binding motif protein 41 2.52352
CST7 cystatin F (leukocystatin) 2.52348
TPSD1 tryptase delta 1 2.51977
PSORS1C2 psoriasis susceptibility 1 candidate 2 2.51879
PLK3 polo-like kinase 3 2.51783
VNN1 vanin 1 2.51744
LAMB4 laminin, beta 4 2.51721
SH2D2A SH2 domain containing 2A 2.51665
SAA2 serum amyloid A2 2.51446
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2 2.50292
HDAC7 histone deacetylase 7 2.50262
GABARAPL1 GABA(A) receptor-associated protein like 1 2.50169
ATF3 activating transcription factor 3 2.49799
PLSCR2 phospholipid scramblase 2 2.49799
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.49481
PLA2G2F phospholipase A2, group IIF 2.49213
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 2.49061
GIPC1 GIPC PDZ domain containing family, member 1 2.48482
ZNF574 zinc finger protein 574 2.48408
GBA1 glucosylceramidase beta 1 2.48352
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2.48281
BCAT1 branched chain amino-acid transaminase 1, cytosolic 2.48175
POMZP3 POM121 and ZP3 fusion 2.48156
SPATA1 spermatogenesis associated 1 2.47959
BCL7B B-cell CLL/lymphoma 7B 2.47939
PCDH1 protocadherin 1 2.47861
ADAM9 ADAM metallopeptidase domain 9 2.47519
UNC13A unc-13 homolog A (C. elegans) 2.47054
AKAP5 A kinase (PRKA) anchor protein 5 2.46457
MAPK12 mitogen-activated protein kinase 12 2.4641
CYLC2 cylicin, basic protein of sperm head cytoskeleton 2 2.46352
HOXA3 homeobox A3 2.45799
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 2.45631
KEAP1 kelch-like ECH-associated protein 1 2.45445
SPINT1 serine peptidase inhibitor, Kunitz type 1 2.45184
CEP57 centrosomal protein 57kDa 2.45058
CARD14 caspase recruitment domain family, member 14 2.45054
GPR171 G protein-coupled receptor 171 2.44736
BRDT bromodomain, testis-specific 2.44717
CRYGB crystallin, gamma B 2.44659
RASA2 RAS p21 protein activator 2 2.44475
RALB v-ral simian leukemia viral oncogene homolog B 2.44459
ETV6 ets variant 6 2.44119
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa 2.43996
TUBB6 tubulin, beta 6 class V 2.43764
TIMP1 TIMP metallopeptidase inhibitor 1 2.43636
CRISP2 cysteine-rich secretory protein 2 2.43265
MROH7 maestro heat-like repeat family member 7 2.4296
IFRD1 interferon-related developmental regulator 1 2.42911
ETV7 ets variant 7 2.42796
OR7A10 olfactory receptor, family 7, subfamily A, member 10 2.42522
HS3ST3B1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 2.42272
RBM34 RNA binding motif protein 34 2.41839
MBNL2 muscleblind-like splicing regulator 2 2.41684
LPAR4 lysophosphatidic acid receptor 4 2.41437
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 2.41392
ZNF585B zinc finger protein 585B 2.41159
MPPED1 metallophosphoesterase domain containing 1 2.41147
ELL2 elongation factor, RNA polymerase II, 2 2.41008
TIGD6 tigger transposable element derived 6 2.40654
IGF2R insulin-like growth factor 2 receptor 2.40582
GRIK3 glutamate receptor, ionotropic, kainate 3 2.40193
CLEC2D C-type lectin domain family 2, member D 2.40108
TRPV6 transient receptor potential cation channel, subfamily V, member 6 2.39854
BEST1 bestrophin 1 2.39617
DMTF1 cyclin D binding myb-like transcription factor 1 2.39614
GPC1 glypican 1 2.39593
ALOXE3 arachidonate lipoxygenase 3 2.39569
GFI1 growth factor independent 1 transcription repressor 2.39422
ERC2 ELKS/RAB6-interacting/CAST family member 2 2.39367
SEMG2 semenogelin II 2.392
CCR6 chemokine (C-C motif) receptor 6 2.39084
IFNA5 interferon, alpha 5 2.38965
SBDS Shwachman-Bodian-Diamond syndrome 2.38828
DLX6 distal-less homeobox 6 2.38749
DNASE2B deoxyribonuclease II beta 2.38705
MRPS10 mitochondrial ribosomal protein S10 2.38683
AANAT aralkylamine N-acetyltransferase 2.38439
TMEM19 transmembrane protein 19 2.38279
ZNF81 zinc finger protein 81 2.38205
FABP2 fatty acid binding protein 2, intestinal 2.38024
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 2.37986
YIF1B Yip1 interacting factor homolog B (S. cerevisiae) 2.37942
FAM131B family with sequence similarity 131, member B 2.37829
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent 2.37724
CCNJ cyclin J 2.37357
AGBL3 ATP/GTP binding protein-like 3 2.37213
MBTD1 mbt domain containing 1 2.37183
LSR lipolysis stimulated lipoprotein receptor 2.37087
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 2.37051
KRT86 keratin 86, type II 2.36799
SOX4 SRY (sex determining region Y)-box 4 2.363
LIM2 lens intrinsic membrane protein 2, 19kDa 2.36096
PFKP phosphofructokinase, platelet 2.35776
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 2.3562
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 2.3486
N4BP3 NEDD4 binding protein 3 2.34773
GABPB1 GA binding protein transcription factor, beta subunit 1 2.34562
LARP6 La ribonucleoprotein domain family, member 6 2.34464
HLA-DMB major histocompatibility complex, class II, DM beta 2.34324
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 2.33685
SKIC3 SKI3 subunit of superkiller complex 2.33647
PTGES prostaglandin E synthase 2.33282
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 2.33277
ASL argininosuccinate lyase 2.3319
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 2.33126
SCT secretin 2.32564
ATP8B3 ATPase, aminophospholipid transporter, class I, type 8B, member 3 2.32531
FURIN furin (paired basic amino acid cleaving enzyme) 2.32523
KIF21B kinesin family member 21B 2.32356
MAP1B microtubule-associated protein 1B 2.32072
C2CD2 C2 calcium-dependent domain containing 2 2.32054
TACR3 tachykinin receptor 3 2.32043
ITGB5 integrin, beta 5 2.31806
YBX3 Y box binding protein 3 2.31618
MC3R melanocortin 3 receptor 2.31565
ZPR1 ZPR1 zinc finger 2.31391
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 2.31373
CHRNE cholinergic receptor, nicotinic, epsilon (muscle) 2.31365
FBXO22 F-box protein 22 2.31363
HOMER2 homer scaffolding protein 2 2.31296
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 2.31183
LMX1B LIM homeobox transcription factor 1, beta 2.30919
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.30844
IL2RA interleukin 2 receptor, alpha 2.30733
NME8 NME/NM23 family member 8 2.30713
CCDC144A coiled-coil domain containing 144A 2.30509
WBP4 WW domain binding protein 4 2.30419
TSBP1 testis expressed basic protein 1 2.3037
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic 2.30199
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 2.30136
SMR3B submaxillary gland androgen regulated protein 3B 2.30133
NGB neuroglobin 2.30017
AXIN1 axin 1 2.29463
ZNF362 zinc finger protein 362 2.29422
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.29373
MAGEB3 melanoma antigen family B3 2.2936
PSORS1C1 psoriasis susceptibility 1 candidate 1 2.29296
PPIE peptidylprolyl isomerase E (cyclophilin E) 2.29216
ZXDB zinc finger, X-linked, duplicated B 2.28714
GRIK4 glutamate receptor, ionotropic, kainate 4 2.28664
IL4 interleukin 4 2.28646
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 2.28591
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.28157
MINK1 misshapen-like kinase 1 2.28154
COL4A4 collagen, type IV, alpha 4 2.2796
KLRC1 killer cell lectin-like receptor subfamily C, member 1 2.27923
MAGIX MAGI family member, X-linked 2.27775
SERINC1 serine incorporator 1 2.277
TAS2R13 taste receptor, type 2, member 13 2.27602
GDAP1L1 ganglioside induced differentiation associated protein 1-like 1 2.27533
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 2.27424
ZNF780B zinc finger protein 780B 2.27372
TJAP1 tight junction associated protein 1 (peripheral) 2.27238
FAM135A family with sequence similarity 135, member A 2.2722
ELOA2 elongin A2 2.2714
DUSP5 dual specificity phosphatase 5 2.27117
ACOXL acyl-CoA oxidase-like 2.26907
MUC13 mucin 13, cell surface associated 2.26864
PORCN porcupine homolog (Drosophila) 2.26692
ADAM21 ADAM metallopeptidase domain 21 2.26619
RPE65 retinal pigment epithelium-specific protein 65kDa 2.26193
IL5 interleukin 5 2.26119
TRIM23 tripartite motif containing 23 2.26109
IL11 interleukin 11 2.26047
ITGA1 integrin, alpha 1 2.25953
FEZF2 FEZ family zinc finger 2 2.2585
TPD52L2 tumor protein D52-like 2 2.2585
OXCT2 3-oxoacid CoA transferase 2 2.25773
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 2.25608
KYAT3 kynurenine aminotransferase 3 2.25549
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 2.25424
KLF13 Kruppel-like factor 13 2.25417
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 2.25389
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2 2.25014
STBD1 starch binding domain 1 2.24773
PTTG2 pituitary tumor-transforming 2 2.24773
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 2.2477
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 2.24499
GDI1 GDP dissociation inhibitor 1 2.24421
BCL2L13 BCL2-like 13 (apoptosis facilitator) 2.24417
SEMG1 semenogelin I 2.24106
CHD1 chromodomain helicase DNA binding protein 1 2.24071
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.23997
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 2.23981
IL36R interleukin 36 receptor 2.23842
CD8A CD8a molecule 2.23823
KDM5C lysine (K)-specific demethylase 5C 2.23814
POU6F1 POU class 6 homeobox 1 2.23594
ZNHIT6 zinc finger, HIT-type containing 6 2.23553
CBARP CACN subunit beta associated regulatory protein 2.23527
KRT37 keratin 37, type I 2.23513
PARD6B par-6 family cell polarity regulator beta 2.23304
ZNF674 zinc finger protein 674 2.23274
CIZ1 CDKN1A interacting zinc finger protein 1 2.23218
FGF12 fibroblast growth factor 12 2.23215
KLRC3 killer cell lectin-like receptor subfamily C, member 3 2.23162
RO60 Ro60, Y RNA binding protein 2.22762
OR10H3 olfactory receptor, family 10, subfamily H, member 3 2.2257
SMAD3 SMAD family member 3 2.22469
TCF15 transcription factor 15 (basic helix-loop-helix) 2.22413
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma 2.22076
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1) 2.21816
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa 2.21792
PIGB phosphatidylinositol glycan anchor biosynthesis, class B 2.21354
DNM2 dynamin 2 2.21193
GREM1 gremlin 1, DAN family BMP antagonist 2.2107
ANKRD11 ankyrin repeat domain 11 2.21006
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 2.20959
PCNX1 pecanex 1 2.20959
NPHP1 nephronophthisis 1 (juvenile) 2.20937
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 2.20883
GCM2 glial cells missing homolog 2 (Drosophila) 2.20739
PELO pelota homolog (Drosophila) 2.20626
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme 2.2048
GFM1 G elongation factor, mitochondrial 1 2.20451
TEAD3 TEA domain family member 3 2.20333
HBS1L HBS1-like translational GTPase 2.20274
AFDN afadin, adherens junction formation factor 2.20123
DRD3 dopamine receptor D3 2.1983
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 2.19699
EFCC1 EF-hand and coiled-coil domain containing 1 2.19505
ZNF234 zinc finger protein 234 2.19372
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 2.19352
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 2.18897
ZNF343 zinc finger protein 343 2.18749
CDH9 cadherin 9, type 2 (T1-cadherin) 2.18745
TNFAIP8L2-SCNM1 TNFAIP8L2-SCNM1 readthrough 2.18701
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1 2.18566
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) 2.18426
PKD2L2 polycystic kidney disease 2-like 2 2.18328
MRPL37 mitochondrial ribosomal protein L37 2.18233
CHD6 chromodomain helicase DNA binding protein 6 2.18208
BEAN1 brain expressed, associated with NEDD4, 1 2.18155
HEBP2 heme binding protein 2 2.18137
ZNF23 zinc finger protein 23 2.18108
CCDC57 coiled-coil domain containing 57 2.18039
PEDS1 plasmanylethanolamine desaturase 1 2.17986
IRAK1 interleukin-1 receptor-associated kinase 1 2.17894
ACTN4 actinin, alpha 4 2.17872
ASCC1 activating signal cointegrator 1 complex subunit 1 2.17473
PURG purine-rich element binding protein G 2.17363
KIF24 kinesin family member 24 2.17332
FXYD5 FXYD domain containing ion transport regulator 5 2.17268
PACC1 proton activated chloride channel 1 2.17243
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 2.1716
CRX cone-rod homeobox 2.17087
MGLL monoglyceride lipase 2.17086
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 2.17028
RBP3 retinol binding protein 3, interstitial 2.16996
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 2.16969
IMPG1 interphotoreceptor matrix proteoglycan 1 2.16937
SLC25A30 solute carrier family 25, member 30 2.16353
KISS1 KiSS-1 metastasis-suppressor 2.16147
TTC22 tetratricopeptide repeat domain 22 2.16037
TSC22D4 TSC22 domain family, member 4 2.15991
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa 2.15929
NPPA natriuretic peptide A 2.15876
RAI14 retinoic acid induced 14 2.15704
PRICKLE3 prickle homolog 3 (Drosophila) 2.15694
ANXA11 annexin A11 2.15653
AFAP1 actin filament associated protein 1 2.15621
FAM13C family with sequence similarity 13, member C 2.15615
S1PR2 sphingosine-1-phosphate receptor 2 2.15468
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 2.15194
ATP11B ATPase, class VI, type 11B 2.1501
STON1-GTF2A1L STON1-GTF2A1L readthrough 2.14997
CCSER2 coiled-coil serine-rich protein 2 2.14863
DGKB diacylglycerol kinase, beta 90kDa 2.14779
TMC7 transmembrane channel-like 7 2.14762
ZNF682 zinc finger protein 682 2.14737
HID1 HID1 domain containing 2.14648
MEF2D myocyte enhancer factor 2D 2.14331
IQSEC2 IQ motif and Sec7 domain 2 2.14317
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 2.1426
ADGRG1 adhesion G protein-coupled receptor G1 2.14232
BPY2B basic charge, Y-linked, 2B 2.14149
RB1CC1 RB1-inducible coiled-coil 1 2.14107
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor 2.13912
DDRGK1 DDRGK domain containing 1 2.13895
KRT81 keratin 81, type II 2.13868
NYX nyctalopin 2.13808
ZNF589 zinc finger protein 589 2.13797
HOXB8 homeobox B8 2.13388
PERP PERP, TP53 apoptosis effector 2.13187
FOXD3 forkhead box D3 2.13022
SLITRK2 SLIT and NTRK-like family, member 2 2.12913
FBXO24 F-box protein 24 2.12901
CAMKV CaM kinase-like vesicle-associated 2.12789
ZNF407 zinc finger protein 407 2.12683
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 2.1266
DRD4 dopamine receptor D4 2.12592
AVEN apoptosis, caspase activation inhibitor 2.12569
FILIP1L filamin A interacting protein 1-like 2.12518
ZNF80 zinc finger protein 80 2.12259
RUSC2 RUN and SH3 domain containing 2 2.12148
ONECUT1 one cut homeobox 1 2.11823
ZNF141 zinc finger protein 141 2.11657
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 2.11599
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 2.11407
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 2.11367
ZNF442 zinc finger protein 442 2.11129
TCP11 t-complex 11, testis-specific 2.11103
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4 2.11051
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 2.10994
PAPOLB poly(A) polymerase beta (testis specific) 2.10924
H2AC7 H2A clustered histone 7 2.10896
DHRS3 dehydrogenase/reductase (SDR family) member 3 2.10863
SMR3A submaxillary gland androgen regulated protein 3A 2.1086
CPTP ceramide-1-phosphate transfer protein 2.10689
FOXN1 forkhead box N1 2.10466
NRBF2 nuclear receptor binding factor 2 2.10412
PSG5 pregnancy specific beta-1-glycoprotein 5 2.10395
TICAM1 toll-like receptor adaptor molecule 1 2.10258
MTMR7 myotubularin related protein 7 2.09961
MTNR1B melatonin receptor 1B 2.09961
TMC5 transmembrane channel-like 5 2.09751
SLC49A3 solute carrier family 49 member 3 2.09647
TM4SF4 transmembrane 4 L six family member 4 2.09618
PBOV1 prostate and breast cancer overexpressed 1 2.09484
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 2.09461
SMG5 SMG5 nonsense mediated mRNA decay factor 2.09456
TRPM2 transient receptor potential cation channel, subfamily M, member 2 2.09447
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 2.09436
FGF21 fibroblast growth factor 21 2.09402
OR1A2 olfactory receptor, family 1, subfamily A, member 2 2.09269
CAMK1G calcium/calmodulin-dependent protein kinase IG 2.09105
NPVF neuropeptide VF precursor 2.09051
MGAM2 maltase-glucoamylase 2 (putative) 2.0902
GSC2 goosecoid homeobox 2 2.08997
NHLH2 nescient helix loop helix 2 2.08845
KLHL4 kelch-like family member 4 2.08802
PARP11 poly (ADP-ribose) polymerase family, member 11 2.08791
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 2.08787
COL19A1 collagen, type XIX, alpha 1 2.087
STAP2 signal transducing adaptor family member 2 2.08653
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 2.08599
LGALS13 lectin, galactoside-binding, soluble, 13 2.0859
EXO5 exonuclease 5 2.0853
OR3A2 olfactory receptor, family 3, subfamily A, member 2 2.0834
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 2.08275
YJU2B YJU2 splicing factor homolog B 2.08187
MTRF1 mitochondrial translational release factor 1 2.07799
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 2.07791
PAEP progestagen-associated endometrial protein 2.07751
TP53TG5 TP53 target 5 2.07723
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 2.07683
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 2.07624
TCP11L1 t-complex 11, testis-specific-like 1 2.0746
USP53 ubiquitin specific peptidase 53 2.07387
TNR tenascin R 2.07333
SNX13 sorting nexin 13 2.07233
OR2J3 olfactory receptor, family 2, subfamily J, member 3 2.07223
WDR13 WD repeat domain 13 2.07215
ARID5B AT rich interactive domain 5B (MRF1-like) 2.07194
MSI1 musashi RNA-binding protein 1 2.07145
BUD31 BUD31 homolog (S. cerevisiae) 2.07103
RSF1 remodeling and spacing factor 1 2.07066
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1 2.07001
BECN1 beclin 1, autophagy related 2.06891
IER2 immediate early response 2 2.06662
RFPL1 ret finger protein-like 1 2.06563
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 2.06528
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 2.06522
PAPPA pregnancy-associated plasma protein A, pappalysin 1 2.06461
GPR25 G protein-coupled receptor 25 2.06276
PLAUR plasminogen activator, urokinase receptor 2.0626
CRYBA1 crystallin, beta A1 2.06251
MLNR motilin receptor 2.06043
LAIR2 leukocyte-associated immunoglobulin-like receptor 2 2.05948
LOC122526780 uncharacterized LOC122526780 2.05911
ITCH itchy E3 ubiquitin protein ligase 2.05799
BRSK2 BR serine/threonine kinase 2 2.0579
TMEM184B transmembrane protein 184B 2.05779
PRDM14 PR domain containing 14 2.05652
FAM50A family with sequence similarity 50, member A 2.05635
ZNF586 zinc finger protein 586 2.05607
TMEM50A transmembrane protein 50A 2.05518
PAQR5 progestin and adipoQ receptor family member V 2.05504
CAPN2 calpain 2, (m/II) large subunit 2.05413
IL2 interleukin 2 2.05263
OR10H2 olfactory receptor, family 10, subfamily H, member 2 2.05262
ICAM5 intercellular adhesion molecule 5, telencephalin 2.05167
NUP58 nucleoporin 58 2.0513
GPATCH8 G patch domain containing 8 2.05051
ATXN3L ataxin 3-like 2.04827
FIP1L1 factor interacting with PAPOLA and CPSF1 2.04813
BMP10 bone morphogenetic protein 10 2.04735
MYO3A myosin IIIA 2.04572
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 2.04526
ZNF613 zinc finger protein 613 2.04521
VGLL4 vestigial-like family member 4 2.04508
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 2.0447
CHN1 chimerin 1 2.04413
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 2.04344
TRAPPC14 trafficking protein particle complex subunit 14 2.04251
GAN gigaxonin 2.04092
AIRIM AFG2 interacting ribosome maturation factor 2.04056
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12 2.03951
CDH20 cadherin 20, type 2 2.03934
DVL1 dishevelled segment polarity protein 1 2.03918
LPGAT1 lysophosphatidylglycerol acyltransferase 1 2.03726
WDR44 WD repeat domain 44 2.03662
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 2.0364
ANXA1 annexin A1 2.03635
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 2.03628
GFER growth factor, augmenter of liver regeneration 2.03546
LRRTM2 leucine rich repeat transmembrane neuronal 2 2.03271
DOCK3 dedicator of cytokinesis 3 2.03166
OR11A1 olfactory receptor, family 11, subfamily A, member 1 2.03113
CSNK1G1 casein kinase 1, gamma 1 2.02938
MORC1 MORC family CW-type zinc finger 1 2.02739
TRPV4 transient receptor potential cation channel, subfamily V, member 4 2.02341
ZNF549 zinc finger protein 549 2.02274
RCAN3 RCAN family member 3 2.02193
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 2.02165
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 2.0215
CLIP1 CAP-GLY domain containing linker protein 1 2.0208
NIT1 nitrilase 1 2.02037
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 2.01985
FOXG1 forkhead box G1 2.01958
PTPRK protein tyrosine phosphatase, receptor type, K 2.01893
PADI4 peptidyl arginine deiminase, type IV 2.01839
ATG12 autophagy related 12 2.0183
GLRA3 glycine receptor, alpha 3 2.01703
ADAM29 ADAM metallopeptidase domain 29 2.01701
CLIP4 CAP-GLY domain containing linker protein family, member 4 2.01684
MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2.01652
FBXO28 F-box protein 28 2.01595
MYH15 myosin, heavy chain 15 2.01524
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 2.01363
NMU neuromedin U 2.01345
RASAL2 RAS protein activator like 2 2.01336
MNT MAX network transcriptional repressor 2.01307
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2 2.01192
FICD FIC domain containing 2.01161
CHRM2 cholinergic receptor, muscarinic 2 2.01128
PTCRA pre T-cell antigen receptor alpha 2.01107
DGKI diacylglycerol kinase, iota 2.0101
IL18RAP interleukin 18 receptor accessory protein 2.00876
GADD45A growth arrest and DNA-damage-inducible, alpha 2.00814
PNKD paroxysmal nonkinesigenic dyskinesia 2.00508
ZNF532 zinc finger protein 532 2.0025
IGFBP1 insulin-like growth factor binding protein 1 2.0021
PITPNM3 PITPNM family member 3 2.00207
ALX3 ALX homeobox 3 2.00147

decreased expression

Symbol Name Standardized Value
B4GAT1 beta-1,4-glucuronyltransferase 1 -10.0
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -8.56784
TCTN1 tectonic family member 1 -8.38162
PGM1 phosphoglucomutase 1 -8.15172
CD320 CD320 molecule -8.1352
ALDOC aldolase C, fructose-bisphosphate -8.06946
FGFR4 fibroblast growth factor receptor 4 -7.8619
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -7.63511
HAT1 histone acetyltransferase 1 -7.59256
STMN1 stathmin 1 -7.27595
PGAM4 phosphoglycerate mutase family member 4 -7.00128
PCCB propionyl CoA carboxylase, beta polypeptide -6.91438
CDC20 cell division cycle 20 -6.86819
LDHD lactate dehydrogenase D -6.68976
TMEM109 transmembrane protein 109 -6.59999
GTF2A2 general transcription factor IIA, 2, 12kDa -6.49199
FBXL12 F-box and leucine-rich repeat protein 12 -6.40336
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -6.3418
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -6.33495
MELK maternal embryonic leucine zipper kinase -6.26133
PSRC1 proline/serine-rich coiled-coil 1 -6.16127
CCNA2 cyclin A2 -6.13139
PARP1 poly (ADP-ribose) polymerase 1 -6.08408
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -6.05008
COG7 component of oligomeric golgi complex 7 -5.85295
NUP85 nucleoporin 85kDa -5.82115
ISOC1 isochorismatase domain containing 1 -5.79804
ZW10 zw10 kinetochore protein -5.795
BLCAP bladder cancer associated protein -5.65144
HMGA2 high mobility group AT-hook 2 -5.60517
CDK1 cyclin-dependent kinase 1 -5.46495
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -5.32878
AURKB aurora kinase B -5.307
SOAT2 sterol O-acyltransferase 2 -5.265
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -5.24272
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -5.23242
PLK1 polo-like kinase 1 -5.07167
POLR1A polymerase (RNA) I polypeptide A, 194kDa -4.98524
ADI1 acireductone dioxygenase 1 -4.9391
TMEM97 transmembrane protein 97 -4.86363
RPIA ribose 5-phosphate isomerase A -4.75976
BIRC5 baculoviral IAP repeat containing 5 -4.67221
TOP2A topoisomerase (DNA) II alpha 170kDa -4.59899
CCNB1 cyclin B1 -4.49019
ICAM3 intercellular adhesion molecule 3 -4.47642
MYCBP MYC binding protein -4.46389
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -4.44672
HADH hydroxyacyl-CoA dehydrogenase -4.42564
ECH1 enoyl CoA hydratase 1, peroxisomal -4.39706
LBR lamin B receptor -4.37141
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -4.33383
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -4.25476
EED embryonic ectoderm development -4.18464
TARBP1 TAR (HIV-1) RNA binding protein 1 -4.15931
CHEK2 checkpoint kinase 2 -4.09277
HSPB1 heat shock 27kDa protein 1 -4.07542
MLEC malectin -4.05045
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.93674
PGRMC1 progesterone receptor membrane component 1 -3.87543
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -3.87315
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -3.86971
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -3.85548
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -3.84734
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.83216
TRAP1 TNF receptor-associated protein 1 -3.78831
ASF1B anti-silencing function 1B histone chaperone -3.78475
TFDP1 transcription factor Dp-1 -3.77333
TARBP2 TAR (HIV-1) RNA binding protein 2 -3.75166
DERA deoxyribose-phosphate aldolase (putative) -3.61629
CCNB2 cyclin B2 -3.61262
TSPAN4 tetraspanin 4 -3.53899
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -3.51099
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -3.47862
MRPL12 mitochondrial ribosomal protein L12 -3.47629
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -3.45455
SCARB1 scavenger receptor class B, member 1 -3.44239
FEN1 flap structure-specific endonuclease 1 -3.42623
KIFC1 kinesin family member C1 -3.40724
NLRP2B NLR family pyrin domain containing 2B -3.36099
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.34851
LOC124907782 dual specificity protein phosphatase 22 -3.33982
ZNF274 zinc finger protein 274 -3.32705
TSPAN3 tetraspanin 3 -3.31044
NT5DC2 5'-nucleotidase domain containing 2 -3.29974
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -3.29939
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -3.28293
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -3.27651
DDB2 damage-specific DNA binding protein 2, 48kDa -3.27625
MRPL39 mitochondrial ribosomal protein L39 -3.27241
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -3.27129
GINS2 GINS complex subunit 2 (Psf2 homolog) -3.2574
DEXI Dexi homolog (mouse) -3.24006
TBC1D10C TBC1 domain family, member 10C -3.2334
RFC5 replication factor C (activator 1) 5, 36.5kDa -3.162
AKAP8 A kinase (PRKA) anchor protein 8 -3.11911
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 -3.10192
PLA2G15 phospholipase A2, group XV -3.07751
KIF15 kinesin family member 15 -3.05182
TMEM14A transmembrane protein 14A -3.0415
PXMP2 peroxisomal membrane protein 2, 22kDa -3.03642
ZDHHC6 zinc finger, DHHC-type containing 6 -3.03558
UNC119B unc-119 homolog B (C. elegans) -3.02396
TK1 thymidine kinase 1, soluble -3.0215
EGF epidermal growth factor -3.01684
HTD2 hydroxyacyl-thioester dehydratase type 2 -3.01146
USP6NL USP6 N-terminal like -3.00589
TRIP13 thyroid hormone receptor interactor 13 -3.00098
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -2.99251
FANCI Fanconi anemia, complementation group I -2.97913
MIS18A MIS18 kinetochore protein A -2.95487
ARFIP2 ADP-ribosylation factor interacting protein 2 -2.95369
CDCA8 cell division cycle associated 8 -2.95189
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 -2.9517
CDC45 cell division cycle 45 -2.94467
PRCP prolylcarboxypeptidase (angiotensinase C) -2.94138
NUP107 nucleoporin 107kDa -2.92653
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -2.92372
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -2.9191
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -2.90477
MRPL17 mitochondrial ribosomal protein L17 -2.90335
MSH6 mutS homolog 6 -2.90105
TEDC2 tubulin epsilon and delta complex 2 -2.88971
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.884
THAP11 THAP domain containing 11 -2.88233
BMP4 bone morphogenetic protein 4 -2.86975
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.84493
EMC9 ER membrane protein complex subunit 9 -2.84087
STAT1 signal transducer and activator of transcription 1, 91kDa -2.83643
NIPSNAP1 nipsnap homolog 1 (C. elegans) -2.83231
PAGR1 PAXIP1 associated glutamate-rich protein 1 -2.82585
MRPS7 mitochondrial ribosomal protein S7 -2.80654
S100A4 S100 calcium binding protein A4 -2.7938
TRIL TLR4 interactor with leucine-rich repeats -2.79041
NCAPD2 non-SMC condensin I complex, subunit D2 -2.78962
CDK4 cyclin-dependent kinase 4 -2.78736
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) -2.78518
TMCO1 transmembrane and coiled-coil domains 1 -2.77676
ORC6 origin recognition complex, subunit 6 -2.7686
DSCC1 DNA replication and sister chromatid cohesion 1 -2.76285
RAD54L RAD54-like (S. cerevisiae) -2.76181
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.75571
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa -2.7543
KIF4A kinesin family member 4A -2.75425
NUP62 nucleoporin 62kDa -2.74967
CENPX centromere protein X -2.7476
PIGF phosphatidylinositol glycan anchor biosynthesis, class F -2.74183
OAZ2 ornithine decarboxylase antizyme 2 -2.73398
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -2.72612
UNC119 unc-119 homolog (C. elegans) -2.71937
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa -2.70802
LUM lumican -2.70783
COPS7A COP9 signalosome subunit 7A -2.6987
NCAPH non-SMC condensin I complex, subunit H -2.69584
TSPAN6 tetraspanin 6 -2.68856
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -2.68579
HSPA1A heat shock 70kDa protein 1A -2.68102
UBE2C ubiquitin-conjugating enzyme E2C -2.67388
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.66871
GAMT guanidinoacetate N-methyltransferase -2.66517
FANCG Fanconi anemia, complementation group G -2.6628
OXA1L oxidase (cytochrome c) assembly 1-like -2.65979
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -2.65879
MRPL35 mitochondrial ribosomal protein L35 -2.65057
MRPL16 mitochondrial ribosomal protein L16 -2.64395
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.64354
CENPS-CORT CENPS-CORT readthrough -2.64034
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -2.62794
PRMT1 protein arginine methyltransferase 1 -2.61977
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -2.61956
SALL2 spalt-like transcription factor 2 -2.61494
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 -2.61476
SRSF3 serine/arginine-rich splicing factor 3 -2.61404
RBM14-RBM4 RBM14-RBM4 readthrough -2.61265
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -2.60999
COL3A1 collagen, type III, alpha 1 -2.60645
HNRNPM heterogeneous nuclear ribonucleoprotein M -2.60478
XPO1 exportin 1 -2.60315
HMOX1 heme oxygenase 1 -2.59924
MDH1 malate dehydrogenase 1, NAD (soluble) -2.59864
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.59331
GAA glucosidase, alpha; acid -2.58622
MCM10 minichromosome maintenance complex component 10 -2.57942
PPIC peptidylprolyl isomerase C (cyclophilin C) -2.57714
LMNB1 lamin B1 -2.57143
NAP1L4 nucleosome assembly protein 1-like 4 -2.56766
MGST2 microsomal glutathione S-transferase 2 -2.55618
SH3D19 SH3 domain containing 19 -2.55379
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.54472
SOSTDC1 sclerostin domain containing 1 -2.54406
CRTAP cartilage associated protein -2.53765
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -2.53285
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -2.52594
UQCRC2 ubiquinol-cytochrome c reductase core protein II -2.50694
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -2.50483
C2CD5 C2 calcium-dependent domain containing 5 -2.50364
QTRT1 queuine tRNA-ribosyltransferase 1 -2.50296
ENY2 enhancer of yellow 2 homolog (Drosophila) -2.50291
PTGER4 prostaglandin E receptor 4 (subtype EP4) -2.50286
UBE2N ubiquitin-conjugating enzyme E2N -2.50127
S100A9 S100 calcium binding protein A9 -2.50031
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -2.489
CDC6 cell division cycle 6 -2.48846
CENPA centromere protein A -2.48147
NNT nicotinamide nucleotide transhydrogenase -2.47399
ANAPC15 anaphase promoting complex subunit 15 -2.47071
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.46566
CRYZ crystallin, zeta (quinone reductase) -2.46485
HIRA histone cell cycle regulator -2.46411
MSH2 mutS homolog 2 -2.45761
MSMO1 methylsterol monooxygenase 1 -2.45718
PCOLCE procollagen C-endopeptidase enhancer -2.45065
CXCL14 chemokine (C-X-C motif) ligand 14 -2.44637
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -2.43956
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.43428
TRAPPC3 trafficking protein particle complex 3 -2.42859
CRELD2 cysteine-rich with EGF-like domains 2 -2.42651
CCDC47 coiled-coil domain containing 47 -2.4201
TMEM177 transmembrane protein 177 -2.41895
FABP5 fatty acid binding protein 5 (psoriasis-associated) -2.40783
CETN3 centrin, EF-hand protein, 3 -2.40567
SLC61A1 solute carrier family 61 member 1 -2.39231
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -2.39107
COG4 component of oligomeric golgi complex 4 -2.39103
SPPL2A signal peptide peptidase like 2A -2.3894
FASTKD5 FAST kinase domains 5 -2.38635
GYS1 glycogen synthase 1 (muscle) -2.38584
STIMATE STIM activating enhancer -2.37764
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 -2.37626
MYH10 myosin, heavy chain 10, non-muscle -2.37457
CDCA3 cell division cycle associated 3 -2.37267
PPIF peptidylprolyl isomerase F -2.36225
UNG uracil-DNA glycosylase -2.36169
MX2 MX dynamin-like GTPase 2 -2.35884
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 -2.35516
KIF18B kinesin family member 18B -2.35222
UXT ubiquitously-expressed, prefoldin-like chaperone -2.35163
DUT deoxyuridine triphosphatase -2.34746
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.34199
VAV3 vav 3 guanine nucleotide exchange factor -2.33742
LAGE3 L antigen family, member 3 -2.32892
CENPM centromere protein M -2.32767
RMI1 RecQ mediated genome instability 1 -2.31688
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.31518
ELP5 elongator acetyltransferase complex subunit 5 -2.31112
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.30991
TMEM9B TMEM9 domain family, member B -2.30873
BEX3 brain expressed X-linked 3 -2.30411
UBE3C ubiquitin protein ligase E3C -2.29799
TSEN2 TSEN2 tRNA splicing endonuclease subunit -2.29776
PRPF31 pre-mRNA processing factor 31 -2.29267
EMP2 epithelial membrane protein 2 -2.27825
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor -2.27637
GJA1 gap junction protein, alpha 1, 43kDa -2.26997
RALY RALY heterogeneous nuclear ribonucleoprotein -2.26655
KDM3A lysine (K)-specific demethylase 3A -2.26654
GPC3 glypican 3 -2.26371
CCNE1 cyclin E1 -2.25934
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -2.25726
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) -2.25102
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit -2.24729
ERCC6L excision repair cross-complementation group 6-like -2.24186
POLK polymerase (DNA directed) kappa -2.24134
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -2.23658
NCAPG2 non-SMC condensin II complex, subunit G2 -2.2358
SSBP2 single-stranded DNA binding protein 2 -2.23034
ADGRA3 adhesion G protein-coupled receptor A3 -2.22424
SKIC8 SKI8 subunit of superkiller complex -2.22244
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -2.21893
MRPL11 mitochondrial ribosomal protein L11 -2.21729
NGRN neugrin, neurite outgrowth associated -2.21669
THADA thyroid adenoma associated -2.21531
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -2.21468
CDC25A cell division cycle 25A -2.20622
RPUSD2 RNA pseudouridylate synthase domain containing 2 -2.20475
OIP5 Opa interacting protein 5 -2.20205
MAGEH1 melanoma antigen family H1 -2.20183
TCEAL9 transcription elongation factor A like 9 -2.2009
PMPCA peptidase (mitochondrial processing) alpha -2.20026
LMAN2L lectin, mannose-binding 2-like -2.19976
UBL5 ubiquitin-like 5 -2.19543
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -2.19327
ATP5MC3 ATP synthase membrane subunit c locus 3 -2.18887
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -2.18562
DENND2D DENN/MADD domain containing 2D -2.18289
SNX1 sorting nexin 1 -2.17437
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -2.17351
VEGFD vascular endothelial growth factor D -2.17252
GPHN gephyrin -2.1659
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -2.16507
STIL SCL/TAL1 interrupting locus -2.15422
AURKA aurora kinase A -2.15066
FUS FUS RNA binding protein -2.14943
NASP nuclear autoantigenic sperm protein (histone-binding) -2.1485
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 -2.14651
MFAP1 microfibrillar-associated protein 1 -2.14484
ELAVL1 ELAV like RNA binding protein 1 -2.14245
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -2.14238
IGSF3 immunoglobulin superfamily, member 3 -2.13477
POLR2G polymerase (RNA) II (DNA directed) polypeptide G -2.13012
TMEM243 transmembrane protein 243, mitochondrial -2.12879
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -2.12675
FZD7 frizzled class receptor 7 -2.12344
BBS1 Bardet-Biedl syndrome 1 -2.12174
GLT8D2 glycosyltransferase 8 domain containing 2 -2.12113
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.12004
MFAP3 microfibrillar-associated protein 3 -2.11845
WASF3 WAS protein family, member 3 -2.11523
PROS1 protein S (alpha) -2.11464
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -2.1141
SPDL1 spindle apparatus coiled-coil protein 1 -2.103
HMMR hyaluronan-mediated motility receptor (RHAMM) -2.1021
KIF11 kinesin family member 11 -2.1011
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.09314
CD36 CD36 molecule (thrombospondin receptor) -2.09133
GLT8D1 glycosyltransferase 8 domain containing 1 -2.08413
MRPL19 mitochondrial ribosomal protein L19 -2.07808
TMX1 thioredoxin-related transmembrane protein 1 -2.07211
SORD sorbitol dehydrogenase -2.07064
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) -2.06898
TLCD3A TLC domain containing 3A -2.06554
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.06482
PRR7 proline rich 7 (synaptic) -2.06029
ECHDC2 enoyl CoA hydratase domain containing 2 -2.06015
GATD3 glutamine amidotransferase class 1 domain containing 3 -2.05767
STAMBP STAM binding protein -2.05354
HMG20A high mobility group 20A -2.05216
CETN2 centrin, EF-hand protein, 2 -2.05199
PRPF19 pre-mRNA processing factor 19 -2.05187
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme -2.04205
ISOC2 isochorismatase domain containing 2 -2.04147
PDLIM2 PDZ and LIM domain 2 (mystique) -2.03887
CD58 CD58 molecule -2.03653
WDR77 WD repeat domain 77 -2.03629
PBK PDZ binding kinase -2.02999
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.02779
GSTA4 glutathione S-transferase alpha 4 -2.02313
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A -2.02165
TTC31 tetratricopeptide repeat domain 31 -2.01839
CBR1 carbonyl reductase 1 -2.01363
ANKRD46 ankyrin repeat domain 46 -2.01157
NEK4 NIMA-related kinase 4 -2.01139
TM2D3 TM2 domain containing 3 -2.00883
MXRA5 matrix-remodelling associated 5 -2.00614
CCS copper chaperone for superoxide dismutase -2.00207