CRCGN012_HEPG2_24H:J22 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description ethyl 2-{(3z)-6-(ethylamino)-3-[(z)-ethylimino]-2,7-dimethyl-3h-xanthen-9-yl}benzoate hydrochloride 2.56 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

840 genes differentially expressed following the CRCGN012_HEPG2_24H:J22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 10.0
TXNRD1 thioredoxin reductase 1 9.6669
INPP1 inositol polyphosphate-1-phosphatase 9.61591
TIMP2 TIMP metallopeptidase inhibitor 2 8.63458
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 7.6741
MICALL1 MICAL-like 1 7.59347
LRP10 low density lipoprotein receptor-related protein 10 7.53681
UBQLN2 ubiquilin 2 7.0586
FOSL1 FOS-like antigen 1 6.93316
LCN2 lipocalin 2 6.93133
IGFBP3 insulin-like growth factor binding protein 3 6.80965
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 6.61523
GPER1 G protein-coupled estrogen receptor 1 6.53343
MVP major vault protein 6.51849
STX1A syntaxin 1A (brain) 6.49812
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 6.41695
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 6.38713
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 6.0684
SQSTM1 sequestosome 1 6.02922
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 5.9827
DDIT4 DNA-damage-inducible transcript 4 5.8787
ADO 2-aminoethanethiol (cysteamine) dioxygenase 5.66701
BZW2 basic leucine zipper and W2 domains 2 5.62738
GFPT1 glutamine--fructose-6-phosphate transaminase 1 5.45204
PTPN12 protein tyrosine phosphatase, non-receptor type 12 5.284
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 5.20094
PPARG peroxisome proliferator-activated receptor gamma 5.13701
NR1H2 nuclear receptor subfamily 1, group H, member 2 5.11925
IER3 immediate early response 3 5.09037
TRIB1 tribbles pseudokinase 1 5.05812
MYC v-myc avian myelocytomatosis viral oncogene homolog 4.93193
ABHD4 abhydrolase domain containing 4 4.92026
IL4R interleukin 4 receptor 4.87464
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 4.85935
AARS1 alanyl-tRNA synthetase 1 4.79323
ZFP36 ZFP36 ring finger protein 4.75608
VAT1 vesicle amine transport 1 4.64514
SARS1 seryl-tRNA synthetase 1 4.63014
PRAF2 PRA1 domain family, member 2 4.49411
ATP11B ATPase, class VI, type 11B 4.48348
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 4.32646
CAMTA2 calmodulin binding transcription activator 2 4.30944
EGR1 early growth response 1 4.28163
ACOT9 acyl-CoA thioesterase 9 4.21147
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 4.2008
PPARD peroxisome proliferator-activated receptor delta 4.17432
GSTZ1 glutathione S-transferase zeta 1 4.14683
SMIM40 small integral membrane protein 40 4.14391
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 4.1374
DSG2 desmoglein 2 4.09591
CAB39 calcium binding protein 39 4.0558
SQOR sulfide quinone oxidoreductase 3.98583
GPATCH8 G patch domain containing 8 3.97732
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 3.95007
YARS1 tyrosyl-tRNA synthetase 1 3.94996
RAB11FIP2 RAB11 family interacting protein 2 (class I) 3.87623
TMEM156 transmembrane protein 156 3.86349
FPGS folylpolyglutamate synthase 3.85673
CASC3 cancer susceptibility candidate 3 3.79962
ADGRE5 adhesion G protein-coupled receptor E5 3.7068
ATOSB atos homolog B 3.69819
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 3.64756
JOSD1 Josephin domain containing 1 3.63173
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent 3.62531
ATF6 activating transcription factor 6 3.62473
FHL2 four and a half LIM domains 2 3.62448
RALB v-ral simian leukemia viral oncogene homolog B 3.61603
TOMM34 translocase of outer mitochondrial membrane 34 3.61092
OSGIN2 oxidative stress induced growth inhibitor family member 2 3.58055
SYNGR3 synaptogyrin 3 3.55298
CIAO3 cytosolic iron-sulfur assembly component 3 3.46674
PHKA1 phosphorylase kinase, alpha 1 (muscle) 3.46638
SHB Src homology 2 domain containing adaptor protein B 3.45375
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 3.43281
TESK1 testis-specific kinase 1 3.43278
TGFB1I1 transforming growth factor beta 1 induced transcript 1 3.42619
PNKP polynucleotide kinase 3'-phosphatase 3.41618
SNX6 sorting nexin 6 3.41574
CNPY3 canopy FGF signaling regulator 3 3.40987
SYF2 SYF2 pre-mRNA-splicing factor 3.38835
NT5E 5'-nucleotidase, ecto (CD73) 3.34786
WDR13 WD repeat domain 13 3.33866
NUP58 nucleoporin 58 3.32329
GIPC1 GIPC PDZ domain containing family, member 1 3.30093
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 3.29881
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 3.27238
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.22917
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 3.22666
ITGB5 integrin, beta 5 3.21873
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 3.21016
PYGB phosphorylase, glycogen; brain 3.2093
TICAM1 toll-like receptor adaptor molecule 1 3.19107
FBXO7 F-box protein 7 3.19035
PRR15L proline rich 15-like 3.17434
RNF113A ring finger protein 113A 3.17097
GFOD1 glucose-fructose oxidoreductase domain containing 1 3.16328
ASCC3 activating signal cointegrator 1 complex subunit 3 3.15886
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 3.15352
PHLDA2 pleckstrin homology-like domain, family A, member 2 3.13451
NPC1 Niemann-Pick disease, type C1 3.12625
EPS8L3 EPS8-like 3 3.1165
PRKCQ protein kinase C, theta 3.10792
SNAP25 synaptosomal-associated protein, 25kDa 3.09284
SPATA7 spermatogenesis associated 7 3.07952
UGDH UDP-glucose 6-dehydrogenase 3.07183
SOX4 SRY (sex determining region Y)-box 4 3.05787
ZYX zyxin 3.04782
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 3.04695
ZFAND1 zinc finger, AN1-type domain 1 3.04419
CSNK1E casein kinase 1, epsilon 3.03675
LGALS8 lectin, galactoside-binding, soluble, 8 3.03326
AXIN1 axin 1 3.03003
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 3.02975
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 3.02915
GLRX glutaredoxin (thioltransferase) 3.02739
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 2.99725
CLIP4 CAP-GLY domain containing linker protein family, member 4 2.99149
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2.97968
FRS2 fibroblast growth factor receptor substrate 2 2.97595
DUSP3 dual specificity phosphatase 3 2.96819
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 2.96707
MTERF3 mitochondrial transcription termination factor 3 2.96182
SNW1 SNW domain containing 1 2.95959
PPIE peptidylprolyl isomerase E (cyclophilin E) 2.94675
TP53BP2 tumor protein p53 binding protein 2 2.93464
DENND4C DENN/MADD domain containing 4C 2.91461
TARS1 threonyl-tRNA synthetase 1 2.90018
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.8977
CDK7 cyclin-dependent kinase 7 2.8851
NANOS3 nanos homolog 3 (Drosophila) 2.8822
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 2.87563
EPHA3 EPH receptor A3 2.86608
MUC13 mucin 13, cell surface associated 2.86078
ARL14 ADP-ribosylation factor-like 14 2.85266
SMAD3 SMAD family member 3 2.85173
ATXN3 ataxin 3 2.8454
LORICRIN loricrin cornified envelope precursor protein 2.8265
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 2.82304
C2CD2 C2 calcium-dependent domain containing 2 2.82188
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 2.81889
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 2.80793
IARS1 isoleucyl-tRNA synthetase 1 2.80759
PRKCD protein kinase C, delta 2.79567
KXD1 KxDL motif containing 1 2.78745
SLC67A1 solute carrier family 67 member 1 2.78569
POLH polymerase (DNA directed), eta 2.76905
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 2.76508
SMG5 SMG5 nonsense mediated mRNA decay factor 2.74801
CST1 cystatin SN 2.74726
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 2.74488
TBC1D15 TBC1 domain family, member 15 2.73715
TNIP2 TNFAIP3 interacting protein 2 2.7293
PSG2 pregnancy specific beta-1-glycoprotein 2 2.72551
TMEM19 transmembrane protein 19 2.70241
RIPPLY2-CYB5R4 RIPPLY2-CYB5R4 readthrough 2.69183
TUT7 terminal uridylyl transferase 7 2.68647
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.68555
RAB3B RAB3B, member RAS oncogene family 2.68277
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 2.68237
POF1B premature ovarian failure, 1B 2.68148
CARS1 cysteinyl-tRNA synthetase 1 2.6806
LGALS4 lectin, galactoside-binding, soluble, 4 2.67528
GDI1 GDP dissociation inhibitor 1 2.67455
KLHL21 kelch-like family member 21 2.67346
P2RY10 purinergic receptor P2Y, G-protein coupled, 10 2.67045
FOXO4 forkhead box O4 2.66817
ARHGAP22 Rho GTPase activating protein 22 2.66569
CGRRF1 cell growth regulator with ring finger domain 1 2.65153
LOC128125814 uncharacterized LOC128125814 2.65112
GET1 guided entry of tail-anchored proteins factor 1 2.64904
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 2.64521
NKIRAS2 NFKB inhibitor interacting Ras-like 2 2.6433
BMAL2 basic helix-loop-helix ARNT like 2 2.64274
YIPF4 Yip1 domain family, member 4 2.63896
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 2.63315
KYAT3 kynurenine aminotransferase 3 2.63314
TM4SF20 transmembrane 4 L six family member 20 2.62836
N4BP3 NEDD4 binding protein 3 2.62829
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 2.62449
BCL7B B-cell CLL/lymphoma 7B 2.62229
NABP1 nucleic acid binding protein 1 2.62062
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.62004
KDM6B lysine (K)-specific demethylase 6B 2.60837
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 2.60766
RPE65 retinal pigment epithelium-specific protein 65kDa 2.59745
TXNL4B thioredoxin-like 4B 2.5944
DYNLT1 dynein, light chain, Tctex-type 1 2.59394
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.59383
PSPC1 paraspeckle component 1 2.59199
SH3GLB1 SH3-domain GRB2-like endophilin B1 2.59167
LARP6 La ribonucleoprotein domain family, member 6 2.58924
CHIC2 cysteine-rich hydrophobic domain 2 2.58205
PDGFA platelet-derived growth factor alpha polypeptide 2.57952
AIRIM AFG2 interacting ribosome maturation factor 2.56886
PIBF1 progesterone immunomodulatory binding factor 1 2.5681
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.56079
MAP7D1 MAP7 domain containing 1 2.56045
H2BC21 H2B clustered histone 21 2.55991
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 2.55841
DRD1 dopamine receptor D1 2.55354
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit 2.55217
TERF2IP telomeric repeat binding factor 2, interacting protein 2.54763
HTRA1 HtrA serine peptidase 1 2.54414
CST2 cystatin SA 2.53059
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) 2.53024
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 2.52953
CLIP1 CAP-GLY domain containing linker protein 1 2.52829
CDK17 cyclin-dependent kinase 17 2.52748
ZBTB6 zinc finger and BTB domain containing 6 2.5237
YY1AP1 YY1 associated protein 1 2.52145
NIT1 nitrilase 1 2.52052
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 2.51934
CCDC68 coiled-coil domain containing 68 2.51605
KIFBP kinesin family binding protein 2.51491
TDRD3 tudor domain containing 3 2.51318
ZZZ3 zinc finger, ZZ-type containing 3 2.5127
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 2.50714
FOXD1 forkhead box D1 2.5033
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 2.50271
R3HCC1L R3H domain and coiled-coil containing 1-like 2.50116
VEZT vezatin, adherens junctions transmembrane protein 2.49941
TRAPPC14 trafficking protein particle complex subunit 14 2.49912
MAGIX MAGI family member, X-linked 2.49798
IL37 interleukin 37 2.49707
ASCC1 activating signal cointegrator 1 complex subunit 1 2.49671
ATF4 activating transcription factor 4 2.49671
TM4SF4 transmembrane 4 L six family member 4 2.49495
EXOC5 exocyst complex component 5 2.49493
PLK3 polo-like kinase 3 2.4947
ARMH3 armadillo like helical domain containing 3 2.48827
ZFP69B ZFP69 zinc finger protein B 2.47919
DIPK1A divergent protein kinase domain 1A 2.4787
MYO1D myosin ID 2.47606
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 2.4752
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 2.47025
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 2.46714
STAP2 signal transducing adaptor family member 2 2.46198
ZBTB35 zinc finger and BTB domain containing 35 2.45744
TIGD6 tigger transposable element derived 6 2.45686
EIF3D eukaryotic translation initiation factor 3, subunit D 2.44573
LPGAT1 lysophosphatidylglycerol acyltransferase 1 2.44332
CERS6 ceramide synthase 6 2.44157
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme 2.43338
EXOC6B exocyst complex component 6B 2.43214
IL5 interleukin 5 2.43138
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 2.4273
GARS1 glycyl-tRNA synthetase 1 2.42531
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 2.42527
RB1CC1 RB1-inducible coiled-coil 1 2.42451
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 2.42426
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 2.42055
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 2.41797
SBDS Shwachman-Bodian-Diamond syndrome 2.41737
OLA1 Obg-like ATPase 1 2.41476
ECD ecdysoneless homolog (Drosophila) 2.41303
GABPB1 GA binding protein transcription factor, beta subunit 1 2.41205
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 2.40797
TJAP1 tight junction associated protein 1 (peripheral) 2.405
RPP38 ribonuclease P/MRP 38kDa subunit 2.40226
SLAMF8 SLAM family member 8 2.39486
SAA2 serum amyloid A2 2.39242
FBXO28 F-box protein 28 2.38497
ELOVL1 ELOVL fatty acid elongase 1 2.38439
DNASE2B deoxyribonuclease II beta 2.37373
KLHL36 kelch-like family member 36 2.37182
MAG myelin associated glycoprotein 2.3684
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.36426
MAPK12 mitogen-activated protein kinase 12 2.36215
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 2.35928
ZNF574 zinc finger protein 574 2.35889
UEVLD UEV and lactate/malate dehyrogenase domains 2.35334
ATP8B4 ATPase, class I, type 8B, member 4 2.35217
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 2.35098
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa 2.34978
FABP2 fatty acid binding protein 2, intestinal 2.34763
HOPX HOP homeobox 2.34642
NGRN neugrin, neurite outgrowth associated 2.3452
GADD45A growth arrest and DNA-damage-inducible, alpha 2.34187
TFE3 transcription factor binding to IGHM enhancer 3 2.34007
SPATA2L spermatogenesis associated 2-like 2.33802
ZNF195 zinc finger protein 195 2.33655
RIOK3 RIO kinase 3 2.3314
YIPF3 Yip1 domain family, member 3 2.33091
PVR poliovirus receptor 2.32919
GTPBP2 GTP binding protein 2 2.32556
SPAG1 sperm associated antigen 1 2.31992
ARL8B ADP-ribosylation factor-like 8B 2.31821
GNA13 guanine nucleotide binding protein (G protein), alpha 13 2.31696
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 2.31664
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.31656
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 2.31563
ALAS1 5'-aminolevulinate synthase 1 2.31383
C6ORF89 chromosome 6 open reading frame 89 2.31283
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.31157
SDC4 syndecan 4 2.31029
CNTNAP3B contactin associated protein-like 3B 2.30683
MNAT1 MNAT CDK-activating kinase assembly factor 1 2.3041
SUN2 Sad1 and UNC84 domain containing 2 2.30207
IPO13 importin 13 2.29957
MBTD1 mbt domain containing 1 2.29906
DUSP6 dual specificity phosphatase 6 2.29514
RHOG ras homolog family member G 2.29511
ZNHIT6 zinc finger, HIT-type containing 6 2.29468
RAP1GAP RAP1 GTPase activating protein 2.29334
WARS1 tryptophanyl-tRNA synthetase 1 2.29283
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 2.29044
TMEM50A transmembrane protein 50A 2.28763
ADAM9 ADAM metallopeptidase domain 9 2.28735
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 2.28675
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 2.2846
UPP1 uridine phosphorylase 1 2.28454
COMMD3 COMM domain containing 3 2.28345
ZNF804A zinc finger protein 804A 2.28248
CLTB clathrin, light chain B 2.27992
CPM carboxypeptidase M 2.27146
ETHE1 ethylmalonic encephalopathy 1 2.27123
ELL2 elongation factor, RNA polymerase II, 2 2.27115
RUFY1 RUN and FYVE domain containing 1 2.27029
NOL8 nucleolar protein 8 2.26938
ZNF141 zinc finger protein 141 2.26649
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 2.26468
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 2.26271
CST4 cystatin S 2.26103
ST18 suppression of tumorigenicity 18, zinc finger 2.25928
PXDC1 PX domain containing 1 2.2575
CHMP4B charged multivesicular body protein 4B 2.25671
BDKRB2 bradykinin receptor B2 2.25644
WIPF1 WAS/WASL interacting protein family, member 1 2.25569
TRPC6 transient receptor potential cation channel, subfamily C, member 6 2.24712
BUD31 BUD31 homolog (S. cerevisiae) 2.24348
ULBP1 UL16 binding protein 1 2.23621
STEEP1 STING1 ER exit protein 1 2.2359
ITGAV integrin, alpha V 2.23019
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa 2.22913
CMKLR2 chemerin chemokine-like receptor 2 2.22734
RNF6 ring finger protein (C3H2C3 type) 6 2.22024
MNT MAX network transcriptional repressor 2.21888
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 2.21765
DOP1B DOP1 leucine zipper like protein B 2.2176
LCOR ligand dependent nuclear receptor corepressor 2.21703
EREG epiregulin 2.21695
LAD1 ladinin 1 2.21314
DUSP5 dual specificity phosphatase 5 2.21267
CREM cAMP responsive element modulator 2.21238
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 2.21224
ELANE elastase, neutrophil expressed 2.21146
EIF5A2 eukaryotic translation initiation factor 5A2 2.21001
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2.20781
SULT1C4 sulfotransferase family, cytosolic, 1C, member 4 2.20383
CCNJ cyclin J 2.20308
SLC38A2 solute carrier family 38, member 2 2.20156
GPC1 glypican 1 2.19989
TAOK3 TAO kinase 3 2.19727
DENND4A DENN/MADD domain containing 4A 2.19376
CLDND1 claudin domain containing 1 2.18555
RTCA RNA 3'-terminal phosphate cyclase 2.18407
IER2 immediate early response 2 2.18338
CLEC5A C-type lectin domain family 5, member A 2.18157
ALOXE3 arachidonate lipoxygenase 3 2.17789
SREK1IP1 SREK1-interacting protein 1 2.17597
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 2.17356
ZNF410 zinc finger protein 410 2.17333
EPS8 epidermal growth factor receptor pathway substrate 8 2.17232
MBNL2 muscleblind-like splicing regulator 2 2.1722
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 2.17186
MTMR6 myotubularin related protein 6 2.17104
CA6 carbonic anhydrase VI 2.17075
CCDC144A coiled-coil domain containing 144A 2.16935
PFDN2 prefoldin subunit 2 2.16913
TSG101 tumor susceptibility 101 2.16635
PPP1R13L protein phosphatase 1, regulatory subunit 13 like 2.16599
KPNA4 karyopherin alpha 4 (importin alpha 3) 2.16538
MOSPD1 motile sperm domain containing 1 2.16457
FXYD5 FXYD domain containing ion transport regulator 5 2.16219
NBR1 neighbor of BRCA1 gene 1 2.1611
SNX16 sorting nexin 16 2.15985
INVS inversin 2.15895
ZC3H15 zinc finger CCCH-type containing 15 2.15869
DHRS3 dehydrogenase/reductase (SDR family) member 3 2.15838
UNC13A unc-13 homolog A (C. elegans) 2.15803
UFM1 ubiquitin-fold modifier 1 2.15711
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 2.15633
SLC26A4 solute carrier family 26 (anion exchanger), member 4 2.15492
WBP4 WW domain binding protein 4 2.15186
FLOT1 flotillin 1 2.15166
VAC14 Vac14 homolog (S. cerevisiae) 2.14789
UBXN7 UBX domain protein 7 2.14764
CBARP CACN subunit beta associated regulatory protein 2.14756
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 2.14565
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 2.13795
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.13699
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.13516
TERF2 telomeric repeat binding factor 2 2.135
METTL25B methyltransferase like 25B 2.13348
PPDPF pancreatic progenitor cell differentiation and proliferation factor 2.12998
VNN1 vanin 1 2.1275
BCL2L13 BCL2-like 13 (apoptosis facilitator) 2.12433
ZNF358 zinc finger protein 358 2.1203
BRSK2 BR serine/threonine kinase 2 2.11913
TFF2 trefoil factor 2 2.11555
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 2.11318
IRAK1 interleukin-1 receptor-associated kinase 1 2.11312
GUCY2C guanylate cyclase 2C 2.1122
YME1L1 YME1-like 1 ATPase 2.1115
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 2.11136
ACTR10 actin-related protein 10 homolog (S. cerevisiae) 2.11134
SH2B3 SH2B adaptor protein 3 2.10947
ASNS asparagine synthetase (glutamine-hydrolyzing) 2.10713
LSG1 large 60S subunit nuclear export GTPase 1 2.10564
RNF220 ring finger protein 220 2.10466
ITPKC inositol-trisphosphate 3-kinase C 2.10368
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F 2.10171
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 2.09902
DTWD1 DTW domain containing 1 2.09582
DMTF1 cyclin D binding myb-like transcription factor 1 2.09357
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 2.09054
PHC2 polyhomeotic homolog 2 (Drosophila) 2.08824
UBR4 ubiquitin protein ligase E3 component n-recognin 4 2.08753
RPL18A ribosomal protein L18a 2.08607
CRK v-crk avian sarcoma virus CT10 oncogene homolog 2.08532
BECN1 beclin 1, autophagy related 2.08435
SLC68A1 solute carrier family 68 member 1 2.08151
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 2.0812
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa 2.07958
MOG myelin oligodendrocyte glycoprotein 2.07865
STON1-GTF2A1L STON1-GTF2A1L readthrough 2.0784
RFK riboflavin kinase 2.07621
RBMX2 RNA binding motif protein, X-linked 2 2.07607
PURG purine-rich element binding protein G 2.07487
SMTN smoothelin 2.0745
MAD2L1BP MAD2L1 binding protein 2.07303
VEGFA vascular endothelial growth factor A 2.07274
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 2.07003
KIAA0513 KIAA0513 2.06976
GBA1 glucosylceramidase beta 1 2.06854
GPBP1L1 GC-rich promoter binding protein 1-like 1 2.06572
NT5M 5',3'-nucleotidase, mitochondrial 2.06445
SOCS2 suppressor of cytokine signaling 2 2.06388
OLAH oleoyl-ACP hydrolase 2.06365
MTMR11 myotubularin related protein 11 2.0631
TEAD3 TEA domain family member 3 2.06307
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5 2.06294
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 2.06279
AARSD1 alanyl-tRNA synthetase domain containing 1 2.06226
CDH8 cadherin 8, type 2 2.06108
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.05722
TMEM144 transmembrane protein 144 2.05646
RRAGC Ras-related GTP binding C 2.05608
ATG14 autophagy related 14 2.05157
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog 2.05144
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 2.04954
IL15RA interleukin 15 receptor, alpha 2.04819
SOX30 SRY (sex determining region Y)-box 30 2.04065
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) 2.0401
EVI2A ecotropic viral integration site 2A 2.03849
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 2.03262
WASHC5 WASH complex subunit 5 2.03064
KIF26B kinesin family member 26B 2.02868
TMUB2 transmembrane and ubiquitin-like domain containing 2 2.02748
KLRC1 killer cell lectin-like receptor subfamily C, member 1 2.02712
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 2.02674
MLH3 mutL homolog 3 2.02667
SLAMF7 SLAM family member 7 2.0262
PPP1R15A protein phosphatase 1, regulatory subunit 15A 2.02579
MEF2D myocyte enhancer factor 2D 2.02485
MAN2A1 mannosidase, alpha, class 2A, member 1 2.02453
ATG2B autophagy related 2B 2.02453
ZNF585B zinc finger protein 585B 2.02418
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 2.02345
GNG12 guanine nucleotide binding protein (G protein), gamma 12 2.02319
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 2.02084
GNPAT glyceronephosphate O-acyltransferase 2.02029
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 2.01887
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 2.01811
PROCR protein C receptor, endothelial 2.01669
REL v-rel avian reticuloendotheliosis viral oncogene homolog 2.01568
GNAT3 guanine nucleotide binding protein, alpha transducing 3 2.01473
H2AC6 H2A clustered histone 6 2.01394
MSTN myostatin 2.0139
RAB8B RAB8B, member RAS oncogene family 2.01376
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 2.01207
H2BC6 H2B clustered histone 6 2.0106
RAB23 RAB23, member RAS oncogene family 2.01006
IRAK4 interleukin-1 receptor-associated kinase 4 2.00739
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 2.00661
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae) 2.00533
JHY junctional cadherin complex regulator 2.00506
TMC5 transmembrane channel-like 5 2.00418
ATP4B ATPase, H+/K+ exchanging, beta polypeptide 2.00193

decreased expression

Symbol Name Standardized Value
NT5DC2 5'-nucleotidase domain containing 2 -10.0
B4GAT1 beta-1,4-glucuronyltransferase 1 -10.0
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -9.43494
CD320 CD320 molecule -9.0435
TCTN1 tectonic family member 1 -8.37876
COG7 component of oligomeric golgi complex 7 -8.35569
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -8.15331
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -8.00303
ADI1 acireductone dioxygenase 1 -7.9381
PGAM4 phosphoglycerate mutase family member 4 -7.68301
NUP85 nucleoporin 85kDa -7.50943
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -7.45219
STMN1 stathmin 1 -7.42317
PGM1 phosphoglucomutase 1 -7.32611
ALDOC aldolase C, fructose-bisphosphate -7.2472
HAT1 histone acetyltransferase 1 -7.23795
PARP1 poly (ADP-ribose) polymerase 1 -7.03812
PSRC1 proline/serine-rich coiled-coil 1 -6.92922
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -6.77608
PLK1 polo-like kinase 1 -6.70545
FGFR4 fibroblast growth factor receptor 4 -6.67992
CCNA2 cyclin A2 -6.38363
THAP11 THAP domain containing 11 -6.23993
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -6.23393
AURKB aurora kinase B -6.15996
ZW10 zw10 kinetochore protein -6.06442
TMEM109 transmembrane protein 109 -6.03886
MELK maternal embryonic leucine zipper kinase -5.73942
ISOC1 isochorismatase domain containing 1 -5.61546
POLR1A polymerase (RNA) I polypeptide A, 194kDa -5.58347
CDK1 cyclin-dependent kinase 1 -5.55885
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -5.53996
PEG10 paternally expressed 10 -5.5266
BLCAP bladder cancer associated protein -5.52641
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -5.45781
GNAS GNAS complex locus -5.31214
HMGA2 high mobility group AT-hook 2 -5.22558
MLEC malectin -5.17964
SOAT2 sterol O-acyltransferase 2 -5.15738
HSPB1 heat shock 27kDa protein 1 -5.05059
BIRC5 baculoviral IAP repeat containing 5 -5.00667
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -4.91462
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -4.85007
TMEM97 transmembrane protein 97 -4.82754
CCNB1 cyclin B1 -4.76452
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -4.73383
CDC20 cell division cycle 20 -4.64663
ASF1B anti-silencing function 1B histone chaperone -4.58951
TARBP1 TAR (HIV-1) RNA binding protein 1 -4.55441
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -4.54886
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -4.53915
TK1 thymidine kinase 1, soluble -4.41365
GTF2A2 general transcription factor IIA, 2, 12kDa -4.37744
TRIP13 thyroid hormone receptor interactor 13 -4.37078
TOP2A topoisomerase (DNA) II alpha 170kDa -4.23797
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -4.23048
ICAM3 intercellular adhesion molecule 3 -4.21883
MIS18A MIS18 kinetochore protein A -4.2059
HADH hydroxyacyl-CoA dehydrogenase -4.1825
ECH1 enoyl CoA hydratase 1, peroxisomal -4.16667
PRCP prolylcarboxypeptidase (angiotensinase C) -4.11211
FEN1 flap structure-specific endonuclease 1 -4.10595
TFDP1 transcription factor Dp-1 -4.09806
TRAP1 TNF receptor-associated protein 1 -4.08185
TBC1D10C TBC1 domain family, member 10C -4.07264
CHEK2 checkpoint kinase 2 -4.04359
AMDHD2 amidohydrolase domain containing 2 -4.02687
RPIA ribose 5-phosphate isomerase A -4.00948
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -3.99425
DDB2 damage-specific DNA binding protein 2, 48kDa -3.93624
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -3.93551
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -3.87712
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -3.87351
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.84982
PGRMC1 progesterone receptor membrane component 1 -3.8446
MRPS7 mitochondrial ribosomal protein S7 -3.79185
RFC5 replication factor C (activator 1) 5, 36.5kDa -3.77672
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -3.75449
BMP4 bone morphogenetic protein 4 -3.7344
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -3.72875
NLRP2B NLR family pyrin domain containing 2B -3.71179
LDHD lactate dehydrogenase D -3.70142
MYCBP MYC binding protein -3.69229
PCCB propionyl CoA carboxylase, beta polypeptide -3.59669
KIFC1 kinesin family member C1 -3.59214
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -3.56148
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.50558
MRPL12 mitochondrial ribosomal protein L12 -3.50285
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -3.49332
RPA3 replication protein A3, 14kDa -3.48681
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -3.44035
MYH10 myosin, heavy chain 10, non-muscle -3.41361
GINS2 GINS complex subunit 2 (Psf2 homolog) -3.4082
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.36169
TEDC2 tubulin epsilon and delta complex 2 -3.34405
EXT1 exostosin glycosyltransferase 1 -3.32918
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -3.32597
GPS1 G protein pathway suppressor 1 -3.26708
BST2 bone marrow stromal cell antigen 2 -3.25934
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -3.25301
EED embryonic ectoderm development -3.24155
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -3.21381
TROAP trophinin associated protein -3.18875
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -3.17149
SHMT1 serine hydroxymethyltransferase 1 (soluble) -3.16962
NNT nicotinamide nucleotide transhydrogenase -3.16454
PAGR1 PAXIP1 associated glutamate-rich protein 1 -3.1514
USP6NL USP6 N-terminal like -3.12469
LBR lamin B receptor -3.11393
SH3D19 SH3 domain containing 19 -3.05212
PDIA6 protein disulfide isomerase family A, member 6 -3.04143
MCM10 minichromosome maintenance complex component 10 -3.04048
STIMATE STIM activating enhancer -3.03436
CTSL cathepsin L -3.03035
EGF epidermal growth factor -3.0268
ABHD14A abhydrolase domain containing 14A -3.02541
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -3.0246
DSCC1 DNA replication and sister chromatid cohesion 1 -3.0164
NCAPH non-SMC condensin I complex, subunit H -3.00659
CDCA3 cell division cycle associated 3 -2.99889
CENPA centromere protein A -2.99871
TMEM106C transmembrane protein 106C -2.99618
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.96334
PXMP2 peroxisomal membrane protein 2, 22kDa -2.95147
CCNF cyclin F -2.937
ORC6 origin recognition complex, subunit 6 -2.93464
CCNB2 cyclin B2 -2.93035
CETN2 centrin, EF-hand protein, 2 -2.89527
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.8916
CDC45 cell division cycle 45 -2.89098
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -2.88683
FZD4 frizzled class receptor 4 -2.83616
LMNB1 lamin B1 -2.8005
TRMT5 tRNA methyltransferase 5 -2.79201
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -2.78984
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.78809
CDC25A cell division cycle 25A -2.78297
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A -2.78291
HSPA1A heat shock 70kDa protein 1A -2.77575
SCAND1 SCAN domain containing 1 -2.76507
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -2.76273
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.75916
CRTAP cartilage associated protein -2.74858
NCAPD2 non-SMC condensin I complex, subunit D2 -2.73087
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.72586
VAV3 vav 3 guanine nucleotide exchange factor -2.70574
FUS FUS RNA binding protein -2.70513
SRSF2 serine/arginine-rich splicing factor 2 -2.702
LIME1 Lck interacting transmembrane adaptor 1 -2.68543
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -2.67916
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.67564
GPC3 glypican 3 -2.67433
MSMO1 methylsterol monooxygenase 1 -2.67014
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.66655
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 -2.66211
WRAP53 WD repeat containing, antisense to TP53 -2.65907
DSN1 DSN1, MIS12 kinetochore complex component -2.64799
ZWINT ZW10 interacting kinetochore protein -2.64542
HNRNPM heterogeneous nuclear ribonucleoprotein M -2.62882
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 -2.61772
FOXM1 forkhead box M1 -2.61171
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -2.59504
COPS7A COP9 signalosome subunit 7A -2.59482
CENPX centromere protein X -2.59405
DUT deoxyuridine triphosphatase -2.59037
DHFR dihydrofolate reductase -2.58378
CHAF1B chromatin assembly factor 1, subunit B (p60) -2.57426
PDIA5 protein disulfide isomerase family A, member 5 -2.57292
PARN poly(A)-specific ribonuclease -2.56735
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -2.56644
CFI complement factor I -2.56621
OIP5 Opa interacting protein 5 -2.56198
KIF11 kinesin family member 11 -2.56075
GAMT guanidinoacetate N-methyltransferase -2.55887
CDC6 cell division cycle 6 -2.55404
KIF15 kinesin family member 15 -2.54547
ICMT isoprenylcysteine carboxyl methyltransferase -2.54531
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.54048
SNX17 sorting nexin 17 -2.54032
UBL5 ubiquitin-like 5 -2.53285
FANCI Fanconi anemia, complementation group I -2.51274
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) -2.51043
RFC3 replication factor C (activator 1) 3, 38kDa -2.50457
CSAD cysteine sulfinic acid decarboxylase -2.5017
KIF4A kinesin family member 4A -2.498
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -2.49267
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) -2.48874
HMGN2 high mobility group nucleosomal binding domain 2 -2.48631
TERT telomerase reverse transcriptase -2.48482
CRELD2 cysteine-rich with EGF-like domains 2 -2.47837
CCND3 cyclin D3 -2.47628
SCGB1D1 secretoglobin, family 1D, member 1 -2.47445
CHAF1A chromatin assembly factor 1, subunit A (p150) -2.45767
DCPS decapping enzyme, scavenger -2.44171
HMOX1 heme oxygenase 1 -2.44139
PYCR3 pyrroline-5-carboxylate reductase 3 -2.43943
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) -2.43677
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G -2.43507
LOC102724594 splicing factor U2AF 35 kDa subunit -2.42937
RAD54L RAD54-like (S. cerevisiae) -2.42926
SRSF3 serine/arginine-rich splicing factor 3 -2.42603
AURKA aurora kinase A -2.42499
ANAPC15 anaphase promoting complex subunit 15 -2.41696
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 -2.41675
TM9SF2 transmembrane 9 superfamily member 2 -2.40727
CHMP6 charged multivesicular body protein 6 -2.40461
PPP4C protein phosphatase 4, catalytic subunit -2.4042
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -2.40316
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -2.40273
ENY2 enhancer of yellow 2 homolog (Drosophila) -2.40139
PDF peptide deformylase (mitochondrial) -2.38849
ARFIP2 ADP-ribosylation factor interacting protein 2 -2.38671
KHK ketohexokinase (fructokinase) -2.37543
UBE2G2 ubiquitin-conjugating enzyme E2G 2 -2.37519
FMO1 flavin containing monooxygenase 1 -2.37445
MSH2 mutS homolog 2 -2.36883
NASP nuclear autoantigenic sperm protein (histone-binding) -2.36723
CENPS-CORT CENPS-CORT readthrough -2.36566
MGST2 microsomal glutathione S-transferase 2 -2.3639
CCNG1 cyclin G1 -2.36218
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 -2.36137
PCNA proliferating cell nuclear antigen -2.35559
COG4 component of oligomeric golgi complex 4 -2.3517
SPAG5 sperm associated antigen 5 -2.35075
MTARC1 mitochondrial amidoxime reducing component 1 -2.34018
TCTA T-cell leukemia translocation altered -2.33999
H2AX H2A.X variant histone -2.33259
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.33214
PPIH peptidylprolyl isomerase H (cyclophilin H) -2.33178
CLDN16 claudin 16 -2.3265
CCDC47 coiled-coil domain containing 47 -2.32409
PIMREG PICALM interacting mitotic regulator -2.32214
PTTG1 pituitary tumor-transforming 1 -2.3212
BCL7C B-cell CLL/lymphoma 7C -2.32092
SOD1 superoxide dismutase 1, soluble -2.31938
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -2.31096
S100A4 S100 calcium binding protein A4 -2.30826
SPDEF SAM pointed domain containing ETS transcription factor -2.30758
ELAVL1 ELAV like RNA binding protein 1 -2.30509
PCNT pericentrin -2.30438
CCNE1 cyclin E1 -2.30335
RBM14-RBM4 RBM14-RBM4 readthrough -2.29611
TM7SF2 transmembrane 7 superfamily member 2 -2.29399
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -2.29246
ARHGAP19 Rho GTPase activating protein 19 -2.28738
HMGN1 high mobility group nucleosome binding domain 1 -2.28367
PCDHB3 protocadherin beta 3 -2.27675
MYO5C myosin VC -2.27431
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -2.27388
MNS1 meiosis-specific nuclear structural 1 -2.27232
GYS1 glycogen synthase 1 (muscle) -2.26922
COQ7 coenzyme Q7 homolog, ubiquinone (yeast) -2.25571
HMGN3 high mobility group nucleosomal binding domain 3 -2.25106
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -2.24939
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.24572
ATP5IF1 ATP synthase inhibitory factor subunit 1 -2.24506
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -2.24265
MCM5 minichromosome maintenance complex component 5 -2.24219
LMAN2L lectin, mannose-binding 2-like -2.23882
TUBA1B tubulin, alpha 1b -2.23569
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -2.23292
IFT81 intraflagellar transport 81 -2.22766
PEBP1 phosphatidylethanolamine binding protein 1 -2.22703
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 -2.22697
ZNF586 zinc finger protein 586 -2.22573
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) -2.2215
UXS1 UDP-glucuronate decarboxylase 1 -2.22047
RFC2 replication factor C (activator 1) 2, 40kDa -2.21923
SCAMP2 secretory carrier membrane protein 2 -2.21412
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme -2.21362
FANCG Fanconi anemia, complementation group G -2.21182
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.21091
SRSF7 serine/arginine-rich splicing factor 7 -2.20911
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -2.20902
CFAP20 cilia and flagella associated protein 20 -2.20846
CLU clusterin -2.2082
ZNF606 zinc finger protein 606 -2.20719
DERA deoxyribose-phosphate aldolase (putative) -2.20418
ZNF544 zinc finger protein 544 -2.19887
AMT aminomethyltransferase -2.19872
NPTN neuroplastin -2.19453
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) -2.19074
NISCH nischarin -2.19058
ITGB1BP1 integrin beta 1 binding protein 1 -2.19016
MCM4 minichromosome maintenance complex component 4 -2.18862
TSPAN6 tetraspanin 6 -2.18511
DHCR7 7-dehydrocholesterol reductase -2.18438
PRUNE1 prune exopolyphosphatase 1 -2.18387
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide -2.17925
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.17521
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor -2.17204
AAAS achalasia, adrenocortical insufficiency, alacrimia -2.16376
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -2.16226
POLE polymerase (DNA directed), epsilon, catalytic subunit -2.16104
FAM111A family with sequence similarity 111, member A -2.15823
SDF2L1 stromal cell-derived factor 2-like 1 -2.15496
SLC39A7 solute carrier family 39 (zinc transporter), member 7 -2.15349
SAMM50 SAMM50 sorting and assembly machinery component -2.14901
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.14617
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -2.1389
NME4 NME/NM23 nucleoside diphosphate kinase 4 -2.13585
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -2.13306
CRYZ crystallin, zeta (quinone reductase) -2.13246
ISOC2 isochorismatase domain containing 2 -2.13173
UBE2C ubiquitin-conjugating enzyme E2C -2.13147
TRIB2 tribbles pseudokinase 2 -2.12451
SLC35H1 solute carrier family 35 member H1 -2.12412
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 -2.12077
ATP5PF ATP synthase peripheral stalk subunit F6 -2.11263
GTPBP3 GTP binding protein 3 (mitochondrial) -2.11172
KANSL1 KAT8 regulatory NSL complex subunit 1 -2.11062
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 -2.10542
TMCO1 transmembrane and coiled-coil domains 1 -2.10344
RHOT2 ras homolog family member T2 -2.1025
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) -2.10157
MRPL30 mitochondrial ribosomal protein L30 -2.10036
KCTD12 potassium channel tetramerization domain containing 12 -2.09948
IL6 interleukin 6 -2.09707
SYBU syntabulin (syntaxin-interacting) -2.09601
ACAA1 acetyl-CoA acyltransferase 1 -2.08628
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -2.08439
TUBB4B tubulin, beta 4B class IVb -2.08429
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.08349
TUBA3E tubulin, alpha 3e -2.08284
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) -2.08213
CTSC cathepsin C -2.07212
SNF8 SNF8, ESCRT-II complex subunit -2.07009
ZNF248 zinc finger protein 248 -2.07002
PRR7 proline rich 7 (synaptic) -2.0691
RMI1 RecQ mediated genome instability 1 -2.06627
SLC2A4RG SLC2A4 regulator -2.06309
DCAF16 DDB1 and CUL4 associated factor 16 -2.0622
TARDBP TAR DNA binding protein -2.05492
NUP93 nucleoporin 93kDa -2.05239
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.05078
CADPS2 Ca++-dependent secretion activator 2 -2.04847
TACC3 transforming, acidic coiled-coil containing protein 3 -2.04502
HMGB2 high mobility group box 2 -2.04344
GLT8D1 glycosyltransferase 8 domain containing 1 -2.04118
ZNF443 zinc finger protein 443 -2.03544
ZNF266 zinc finger protein 266 -2.03333
CPNE3 copine III -2.03182
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -2.03044
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -2.02866
TSEN2 TSEN2 tRNA splicing endonuclease subunit -2.02803
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -2.02447
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.02373
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.02108
CCS copper chaperone for superoxide dismutase -2.01309
GLB1 galactosidase, beta 1 -2.01239
DUSP9 dual specificity phosphatase 9 -2.00147