| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | ethyl 2-{(3z)-6-(ethylamino)-3-[(z)-ethylimino]-2,7-dimethyl-3h-xanthen-9-yl}benzoate hydrochloride 1.28 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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561 genes differentially expressed following the CRCGN012_HEPG2_24H:J23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INPP1 | inositol polyphosphate-1-phosphatase | 9.82876 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 9.27446 |
| TXNRD1 | thioredoxin reductase 1 | 8.51673 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 7.47799 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit | 7.45331 |
| LRP10 | low density lipoprotein receptor-related protein 10 | 7.27471 |
| SQSTM1 | sequestosome 1 | 6.83304 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | 6.76173 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 6.6815 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 6.58974 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 6.51021 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 6.41173 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 6.31234 |
| FOSL1 | FOS-like antigen 1 | 6.10926 |
| STX1A | syntaxin 1A (brain) | 6.07585 |
| MVP | major vault protein | 5.95143 |
| DDIT4 | DNA-damage-inducible transcript 4 | 5.75769 |
| ZFP36 | ZFP36 ring finger protein | 5.6294 |
| IER3 | immediate early response 3 | 5.44709 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | 5.36609 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 5.28128 |
| SQOR | sulfide quinone oxidoreductase | 5.26886 |
| GRB10 | growth factor receptor-bound protein 10 | 5.19831 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 5.15678 |
| CYCS | cytochrome c, somatic | 5.13074 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 5.08347 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.85164 |
| FHL2 | four and a half LIM domains 2 | 4.77564 |
| MICALL1 | MICAL-like 1 | 4.74324 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 4.70004 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 4.65051 |
| AARS1 | alanyl-tRNA synthetase 1 | 4.56739 |
| ACOT9 | acyl-CoA thioesterase 9 | 4.40756 |
| BZW2 | basic leucine zipper and W2 domains 2 | 4.36186 |
| STAP2 | signal transducing adaptor family member 2 | 4.30339 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 4.28426 |
| TRIB1 | tribbles pseudokinase 1 | 4.2399 |
| LCN2 | lipocalin 2 | 4.16761 |
| PNKP | polynucleotide kinase 3'-phosphatase | 4.10522 |
| PRAF2 | PRA1 domain family, member 2 | 4.09864 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 4.06652 |
| NMU | neuromedin U | 4.03796 |
| VAT1 | vesicle amine transport 1 | 4.03 |
| RPL39L | ribosomal protein L39-like | 4.01631 |
| CCL2 | chemokine (C-C motif) ligand 2 | 4.00418 |
| EGR1 | early growth response 1 | 3.99037 |
| YARS1 | tyrosyl-tRNA synthetase 1 | 3.98929 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 3.98202 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | 3.96644 |
| IL4R | interleukin 4 receptor | 3.94668 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 3.94537 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.86101 |
| EPHB2 | EPH receptor B2 | 3.75285 |
| DSG2 | desmoglein 2 | 3.72843 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 3.69903 |
| CCDC92 | coiled-coil domain containing 92 | 3.68 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 3.58016 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 3.55815 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 3.52457 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 3.51935 |
| ABHD4 | abhydrolase domain containing 4 | 3.45204 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 3.43536 |
| SYNGR3 | synaptogyrin 3 | 3.41457 |
| FBXO7 | F-box protein 7 | 3.4027 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 3.39871 |
| ZPR1 | ZPR1 zinc finger | 3.38947 |
| GTF2E2 | general transcription factor IIE, polypeptide 2, beta 34kDa | 3.38076 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 3.33089 |
| TES | testin LIM domain protein | 3.32116 |
| GARS1 | glycyl-tRNA synthetase 1 | 3.31599 |
| SARS1 | seryl-tRNA synthetase 1 | 3.31159 |
| FOXO4 | forkhead box O4 | 3.26402 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 3.26161 |
| MAP7D1 | MAP7 domain containing 1 | 3.1663 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 3.15811 |
| ATF6 | activating transcription factor 6 | 3.13368 |
| NANOS3 | nanos homolog 3 (Drosophila) | 3.12587 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | 3.12205 |
| CAB39 | calcium binding protein 39 | 3.11545 |
| RAP1GAP | RAP1 GTPase activating protein | 3.10547 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 3.08976 |
| RAB11FIP2 | RAB11 family interacting protein 2 (class I) | 3.0835 |
| PPIE | peptidylprolyl isomerase E (cyclophilin E) | 3.06036 |
| SOX4 | SRY (sex determining region Y)-box 4 | 3.0572 |
| H2BC12 | H2B clustered histone 12 | 3.04377 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) | 3.02238 |
| IGF2R | insulin-like growth factor 2 receptor | 3.01673 |
| CDK7 | cyclin-dependent kinase 7 | 3.01389 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 2.98702 |
| VPS11 | vacuolar protein sorting 11 homolog (S. cerevisiae) | 2.93624 |
| LOC128125814 | uncharacterized LOC128125814 | 2.9311 |
| RALB | v-ral simian leukemia viral oncogene homolog B | 2.92621 |
| PRR15L | proline rich 15-like | 2.92062 |
| LARP6 | La ribonucleoprotein domain family, member 6 | 2.89799 |
| OSGIN2 | oxidative stress induced growth inhibitor family member 2 | 2.89112 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | 2.88782 |
| GLRX | glutaredoxin (thioltransferase) | 2.88582 |
| UPP1 | uridine phosphorylase 1 | 2.86202 |
| NUP58 | nucleoporin 58 | 2.84927 |
| CNPY3 | canopy FGF signaling regulator 3 | 2.84407 |
| GNL2 | guanine nucleotide binding protein-like 2 (nucleolar) | 2.83051 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 2.82944 |
| MOG | myelin oligodendrocyte glycoprotein | 2.82917 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 2.82849 |
| CSNK1E | casein kinase 1, epsilon | 2.81732 |
| TRIB3 | tribbles pseudokinase 3 | 2.79445 |
| KIFBP | kinesin family binding protein | 2.78546 |
| ASL | argininosuccinate lyase | 2.77176 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 2.76521 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 2.76444 |
| HAX1 | HCLS1 associated protein X-1 | 2.75829 |
| RNF113A | ring finger protein 113A | 2.75574 |
| ZFP69B | ZFP69 zinc finger protein B | 2.7446 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 2.7405 |
| WDR13 | WD repeat domain 13 | 2.739 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 2.73371 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 | 2.7239 |
| LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) | 2.71891 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 2.70758 |
| HSPBAP1 | HSPB (heat shock 27kDa) associated protein 1 | 2.68869 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 | 2.66764 |
| KIAA0513 | KIAA0513 | 2.66637 |
| LOC102724560 | cystathionine beta-synthase | 2.65974 |
| CSRNP2 | cysteine-serine-rich nuclear protein 2 | 2.65192 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 2.64956 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 2.64912 |
| JOSD1 | Josephin domain containing 1 | 2.63392 |
| SNX6 | sorting nexin 6 | 2.63351 |
| PFDN2 | prefoldin subunit 2 | 2.63044 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 2.62617 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | 2.62553 |
| PPARD | peroxisome proliferator-activated receptor delta | 2.62348 |
| MBNL2 | muscleblind-like splicing regulator 2 | 2.62234 |
| FAM50A | family with sequence similarity 50, member A | 2.59389 |
| ARHGAP22 | Rho GTPase activating protein 22 | 2.5775 |
| PRKCQ | protein kinase C, theta | 2.57656 |
| TRAK2 | trafficking protein, kinesin binding 2 | 2.576 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 2.57228 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 2.56634 |
| TESK1 | testis-specific kinase 1 | 2.54775 |
| MEAF6 | MYST/Esa1-associated factor 6 | 2.5387 |
| CYTH2 | cytohesin 2 | 2.53831 |
| KYAT3 | kynurenine aminotransferase 3 | 2.53656 |
| ATF4 | activating transcription factor 4 | 2.53609 |
| CSK | c-src tyrosine kinase | 2.52486 |
| MAG | myelin associated glycoprotein | 2.51728 |
| CARS1 | cysteinyl-tRNA synthetase 1 | 2.51211 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 2.50731 |
| RNF220 | ring finger protein 220 | 2.50613 |
| ABHD6 | abhydrolase domain containing 6 | 2.50069 |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) | 2.49691 |
| MOBP | myelin-associated oligodendrocyte basic protein | 2.47504 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | 2.46223 |
| IL37 | interleukin 37 | 2.45725 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.45119 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 2.44733 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 2.43621 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 2.43394 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa | 2.43216 |
| NACAD | NAC alpha domain containing | 2.42662 |
| PLK3 | polo-like kinase 3 | 2.42489 |
| WASHC5 | WASH complex subunit 5 | 2.40798 |
| DUSP3 | dual specificity phosphatase 3 | 2.40792 |
| H1-0 | H1.0 linker histone | 2.40221 |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | 2.39972 |
| MNT | MAX network transcriptional repressor | 2.38763 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 2.3848 |
| H2AC6 | H2A clustered histone 6 | 2.37742 |
| TSC22D3 | TSC22 domain family, member 3 | 2.37703 |
| SMAD3 | SMAD family member 3 | 2.37648 |
| DDA1 | DET1 and DDB1 associated 1 | 2.35736 |
| PRKRA | protein kinase, interferon-inducible double stranded RNA dependent activator | 2.35649 |
| CASC3 | cancer susceptibility candidate 3 | 2.35001 |
| BLVRA | biliverdin reductase A | 2.34355 |
| FILIP1L | filamin A interacting protein 1-like | 2.33496 |
| MAP1B | microtubule-associated protein 1B | 2.33391 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 2.33071 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) | 2.32532 |
| PRKCH | protein kinase C, eta | 2.32039 |
| GOLT1A | golgi transport 1A | 2.31775 |
| HKDC1 | hexokinase domain containing 1 | 2.31625 |
| MRPS15 | mitochondrial ribosomal protein S15 | 2.30995 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 2.3095 |
| QTMAN | queuosine-tRNA mannosyltransferase | 2.30843 |
| EMC7 | ER membrane protein complex subunit 7 | 2.30799 |
| LSR | lipolysis stimulated lipoprotein receptor | 2.30783 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 2.30583 |
| EIF3D | eukaryotic translation initiation factor 3, subunit D | 2.3033 |
| RRAGA | Ras-related GTP binding A | 2.29199 |
| KRT81 | keratin 81, type II | 2.28639 |
| JADE2 | jade family PHD finger 2 | 2.2809 |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B | 2.27585 |
| ZYX | zyxin | 2.27455 |
| RAB9A | RAB9A, member RAS oncogene family | 2.26871 |
| PPCS | phosphopantothenoylcysteine synthetase | 2.26746 |
| CORO2B | coronin, actin binding protein, 2B | 2.26652 |
| EIF2B2 | eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa | 2.25834 |
| SUN2 | Sad1 and UNC84 domain containing 2 | 2.25141 |
| PLOD3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | 2.24682 |
| DUSP8 | dual specificity phosphatase 8 | 2.24668 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 2.24588 |
| GIPC1 | GIPC PDZ domain containing family, member 1 | 2.24524 |
| SPATA2L | spermatogenesis associated 2-like | 2.23586 |
| NPC1 | Niemann-Pick disease, type C1 | 2.23575 |
| SLC67A1 | solute carrier family 67 member 1 | 2.23095 |
| CHN1 | chimerin 1 | 2.22646 |
| P2RY10 | purinergic receptor P2Y, G-protein coupled, 10 | 2.22632 |
| ZBTB22 | zinc finger and BTB domain containing 22 | 2.22098 |
| TBC1D15 | TBC1 domain family, member 15 | 2.21464 |
| KRT86 | keratin 86, type II | 2.21388 |
| TMEM144 | transmembrane protein 144 | 2.21062 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 2.20986 |
| EPN2 | epsin 2 | 2.20724 |
| PROCR | protein C receptor, endothelial | 2.20276 |
| BECN1 | beclin 1, autophagy related | 2.19779 |
| UBXN7 | UBX domain protein 7 | 2.18168 |
| CD8A | CD8a molecule | 2.17709 |
| KLRC4-KLRK1 | KLRC4-KLRK1 readthrough | 2.16301 |
| PYGB | phosphorylase, glycogen; brain | 2.16227 |
| VPS26A | vacuolar protein sorting 26 homolog A (S. pombe) | 2.15737 |
| PMS2 | PMS2 postmeiotic segregation increased 2 (S. cerevisiae) | 2.15365 |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 | 2.1536 |
| IMP4 | IMP4, U3 small nucleolar ribonucleoprotein | 2.15321 |
| ALAS1 | 5'-aminolevulinate synthase 1 | 2.14919 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.14813 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 2.14535 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 2.13916 |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 | 2.13839 |
| GPR183 | G protein-coupled receptor 183 | 2.13798 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 2.13759 |
| AARSD1 | alanyl-tRNA synthetase domain containing 1 | 2.1293 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 2.126 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | 2.11584 |
| SHB | Src homology 2 domain containing adaptor protein B | 2.11527 |
| CLCF1 | cardiotrophin-like cytokine factor 1 | 2.11483 |
| VPS4A | vacuolar protein sorting 4 homolog A (S. cerevisiae) | 2.11127 |
| SERINC3 | serine incorporator 3 | 2.11114 |
| TMEM156 | transmembrane protein 156 | 2.1057 |
| GDI1 | GDP dissociation inhibitor 1 | 2.09951 |
| BAG6 | BCL2-associated athanogene 6 | 2.09866 |
| ZNF532 | zinc finger protein 532 | 2.09865 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 2.0908 |
| KLHL21 | kelch-like family member 21 | 2.0871 |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 | 2.07924 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | 2.07506 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 2.07208 |
| MINAR1 | membrane integral NOTCH2 associated receptor 1 | 2.06967 |
| TAOK3 | TAO kinase 3 | 2.06952 |
| XPOT | exportin, tRNA | 2.06537 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 2.06233 |
| KIAA0408 | KIAA0408 | 2.06121 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 2.0612 |
| MGAT4B | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B | 2.05942 |
| MEX3C | mex-3 RNA binding family member C | 2.05913 |
| PORCN | porcupine homolog (Drosophila) | 2.05717 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 2.05348 |
| RABGGTA | Rab geranylgeranyltransferase, alpha subunit | 2.05315 |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 | 2.05276 |
| KEAP1 | kelch-like ECH-associated protein 1 | 2.05162 |
| AKIRIN1 | akirin 1 | 2.05134 |
| PLEC | plectin | 2.05076 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 2.04743 |
| AFAP1 | actin filament associated protein 1 | 2.04579 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 2.04578 |
| KIF21B | kinesin family member 21B | 2.04444 |
| DNM1L | dynamin 1-like | 2.04141 |
| ATP6V1F | ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F | 2.03801 |
| NELFE | negative elongation factor complex member E | 2.03382 |
| CLTB | clathrin, light chain B | 2.03359 |
| GPKOW | G patch domain and KOW motifs | 2.0293 |
| UGDH | UDP-glucose 6-dehydrogenase | 2.02869 |
| ZNF586 | zinc finger protein 586 | 2.02584 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 2.0246 |
| MBTD1 | mbt domain containing 1 | 2.02453 |
| CTAGE8 | CTAGE family, member 8 | 2.02159 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 2.01527 |
| AHNAK2 | AHNAK nucleoprotein 2 | 2.01498 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.01369 |
| ART4 | ADP-ribosyltransferase 4 (Dombrock blood group) | 2.01085 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 2.00822 |
| TMEM39B | transmembrane protein 39B | 2.00605 |
| TMEM19 | transmembrane protein 19 | 2.00471 |
| MYO1D | myosin ID | 2.00253 |
| Symbol | Name | Standardized Value |
|---|---|---|
| B4GAT1 | beta-1,4-glucuronyltransferase 1 | -10.0 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -9.42146 |
| TCTN1 | tectonic family member 1 | -8.64123 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -7.99581 |
| ISOC1 | isochorismatase domain containing 1 | -7.9192 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -7.91872 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -7.63937 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -7.28601 |
| PGM1 | phosphoglucomutase 1 | -7.22525 |
| HAT1 | histone acetyltransferase 1 | -7.22052 |
| MELK | maternal embryonic leucine zipper kinase | -7.11561 |
| ALDOC | aldolase C, fructose-bisphosphate | -7.00141 |
| MRPS2 | mitochondrial ribosomal protein S2 | -6.90716 |
| COG7 | component of oligomeric golgi complex 7 | -6.87346 |
| CDC20 | cell division cycle 20 | -6.86929 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -6.70169 |
| STMN1 | stathmin 1 | -6.66812 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -6.57837 |
| LDHD | lactate dehydrogenase D | -6.53935 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -6.35065 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -6.2894 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -6.22771 |
| PGAM4 | phosphoglycerate mutase family member 4 | -6.22611 |
| ADI1 | acireductone dioxygenase 1 | -6.1291 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | -6.12847 |
| CCNA2 | cyclin A2 | -6.03254 |
| CDK1 | cyclin-dependent kinase 1 | -5.93781 |
| ECH1 | enoyl CoA hydratase 1, peroxisomal | -5.80048 |
| CCNB2 | cyclin B2 | -5.75365 |
| NUP85 | nucleoporin 85kDa | -5.69916 |
| CD320 | CD320 molecule | -5.56502 |
| AURKB | aurora kinase B | -5.54694 |
| TMEM109 | transmembrane protein 109 | -5.50615 |
| DERA | deoxyribose-phosphate aldolase (putative) | -5.43022 |
| POLR1A | polymerase (RNA) I polypeptide A, 194kDa | -5.37506 |
| HADH | hydroxyacyl-CoA dehydrogenase | -5.21561 |
| TMEM97 | transmembrane protein 97 | -5.17639 |
| SOAT2 | sterol O-acyltransferase 2 | -5.10376 |
| PLK1 | polo-like kinase 1 | -4.95447 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | -4.94875 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -4.92843 |
| USP6NL | USP6 N-terminal like | -4.86372 |
| PARP1 | poly (ADP-ribose) polymerase 1 | -4.82738 |
| BIRC5 | baculoviral IAP repeat containing 5 | -4.71865 |
| TFDP1 | transcription factor Dp-1 | -4.58114 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -4.52934 |
| HMGA2 | high mobility group AT-hook 2 | -4.47726 |
| FGFR4 | fibroblast growth factor receptor 4 | -4.46148 |
| MLEC | malectin | -4.44467 |
| MYCBP | MYC binding protein | -4.32182 |
| BLCAP | bladder cancer associated protein | -4.28197 |
| ASF1B | anti-silencing function 1B histone chaperone | -4.224 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | -4.15929 |
| HSPA1A | heat shock 70kDa protein 1A | -4.14041 |
| PCNA | proliferating cell nuclear antigen | -4.04549 |
| PRCP | prolylcarboxypeptidase (angiotensinase C) | -4.03668 |
| ICAM3 | intercellular adhesion molecule 3 | -3.93827 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -3.93512 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -3.9193 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.90439 |
| NUP62 | nucleoporin 62kDa | -3.88644 |
| TK1 | thymidine kinase 1, soluble | -3.88521 |
| LBR | lamin B receptor | -3.87044 |
| RPIA | ribose 5-phosphate isomerase A | -3.77375 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -3.72107 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -3.66616 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.66032 |
| GTF2A2 | general transcription factor IIA, 2, 12kDa | -3.6514 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -3.64644 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -3.57081 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -3.52196 |
| FEN1 | flap structure-specific endonuclease 1 | -3.48576 |
| TEDC2 | tubulin epsilon and delta complex 2 | -3.445 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.42356 |
| THAP11 | THAP domain containing 11 | -3.36892 |
| PIK3R4 | phosphoinositide-3-kinase, regulatory subunit 4 | -3.32416 |
| PGRMC1 | progesterone receptor membrane component 1 | -3.30473 |
| NCAPH | non-SMC condensin I complex, subunit H | -3.2373 |
| SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | -3.23647 |
| TRIP13 | thyroid hormone receptor interactor 13 | -3.23496 |
| FANCG | Fanconi anemia, complementation group G | -3.22852 |
| STIMATE | STIM activating enhancer | -3.20916 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -3.19957 |
| VAV3 | vav 3 guanine nucleotide exchange factor | -3.1966 |
| HMOX1 | heme oxygenase 1 | -3.1845 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.16987 |
| NLRP2B | NLR family pyrin domain containing 2B | -3.15558 |
| PDLIM1 | PDZ and LIM domain 1 | -3.14105 |
| KIF11 | kinesin family member 11 | -3.13487 |
| ZW10 | zw10 kinetochore protein | -3.13414 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | -3.12488 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.11471 |
| TSPAN4 | tetraspanin 4 | -3.11031 |
| ERCC6L | excision repair cross-complementation group 6-like | -3.07575 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -3.06529 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -3.05536 |
| CENPX | centromere protein X | -3.0527 |
| CDC25A | cell division cycle 25A | -3.04364 |
| DSCC1 | DNA replication and sister chromatid cohesion 1 | -3.03522 |
| KIFC1 | kinesin family member C1 | -3.03315 |
| SNRNP25 | small nuclear ribonucleoprotein 25kDa (U11/U12) | -3.01814 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | -3.01788 |
| CCND3 | cyclin D3 | -2.976 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | -2.92208 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | -2.90915 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -2.89976 |
| SDF2L1 | stromal cell-derived factor 2-like 1 | -2.897 |
| CCNF | cyclin F | -2.88957 |
| RACGAP1 | Rac GTPase activating protein 1 | -2.88294 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 | -2.87686 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.87401 |
| CDC6 | cell division cycle 6 | -2.80546 |
| DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) | -2.79294 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | -2.79033 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | -2.77744 |
| SH3D19 | SH3 domain containing 19 | -2.76757 |
| MCM10 | minichromosome maintenance complex component 10 | -2.75021 |
| ZSCAN5A | zinc finger and SCAN domain containing 5A | -2.74351 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 | -2.73628 |
| PRUNE1 | prune exopolyphosphatase 1 | -2.73568 |
| CD58 | CD58 molecule | -2.73392 |
| EGF | epidermal growth factor | -2.71919 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | -2.71801 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.7176 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -2.71317 |
| TBC1D10C | TBC1 domain family, member 10C | -2.69757 |
| ICMT | isoprenylcysteine carboxyl methyltransferase | -2.69649 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) | -2.68238 |
| GAMT | guanidinoacetate N-methyltransferase | -2.67683 |
| CDC45 | cell division cycle 45 | -2.67064 |
| GYS1 | glycogen synthase 1 (muscle) | -2.63555 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -2.62313 |
| CTSL | cathepsin L | -2.61776 |
| NNT | nicotinamide nucleotide transhydrogenase | -2.60911 |
| MSMO1 | methylsterol monooxygenase 1 | -2.6028 |
| UNG | uracil-DNA glycosylase | -2.59237 |
| KHK | ketohexokinase (fructokinase) | -2.59137 |
| PROS1 | protein S (alpha) | -2.59039 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.58452 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | -2.58171 |
| AURKA | aurora kinase A | -2.57801 |
| RMI1 | RecQ mediated genome instability 1 | -2.5716 |
| PARN | poly(A)-specific ribonuclease | -2.55828 |
| KIF15 | kinesin family member 15 | -2.54688 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) | -2.53805 |
| KIF4A | kinesin family member 4A | -2.52368 |
| MICA | MHC class I polypeptide-related sequence A | -2.52362 |
| PRR7 | proline rich 7 (synaptic) | -2.51992 |
| FMO1 | flavin containing monooxygenase 1 | -2.51336 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -2.51199 |
| LMNB1 | lamin B1 | -2.5114 |
| ZWINT | ZW10 interacting kinetochore protein | -2.50917 |
| FIRRM | FIGNL1 interacting regulator of recombination and mitosis | -2.50873 |
| MSH2 | mutS homolog 2 | -2.50778 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | -2.50704 |
| CETN3 | centrin, EF-hand protein, 3 | -2.50219 |
| TLCD3A | TLC domain containing 3A | -2.4982 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine | -2.49357 |
| SPAG5 | sperm associated antigen 5 | -2.47931 |
| TMCO1 | transmembrane and coiled-coil domains 1 | -2.47879 |
| CRLF1 | cytokine receptor-like factor 1 | -2.47593 |
| POLD3 | polymerase (DNA-directed), delta 3, accessory subunit | -2.46726 |
| TMEM14A | transmembrane protein 14A | -2.46226 |
| DUT | deoxyuridine triphosphatase | -2.45475 |
| DEXI | Dexi homolog (mouse) | -2.45169 |
| CDCA8 | cell division cycle associated 8 | -2.44909 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -2.43274 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -2.43261 |
| THEM6 | thioesterase superfamily member 6 | -2.43099 |
| DENND2D | DENN/MADD domain containing 2D | -2.42998 |
| PRRC1 | proline-rich coiled-coil 1 | -2.42742 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) | -2.41374 |
| MSH6 | mutS homolog 6 | -2.39373 |
| POP5 | processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) | -2.38891 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.38655 |
| KIF18B | kinesin family member 18B | -2.3857 |
| XPO1 | exportin 1 | -2.3686 |
| PPIF | peptidylprolyl isomerase F | -2.36787 |
| TRMT5 | tRNA methyltransferase 5 | -2.36697 |
| S100A4 | S100 calcium binding protein A4 | -2.36582 |
| CCNB1 | cyclin B1 | -2.36284 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -2.35965 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -2.34998 |
| ELAVL1 | ELAV like RNA binding protein 1 | -2.34991 |
| CHAF1B | chromatin assembly factor 1, subunit B (p60) | -2.34267 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -2.34233 |
| ZMYM3 | zinc finger, MYM-type 3 | -2.33896 |
| PPIH | peptidylprolyl isomerase H (cyclophilin H) | -2.33336 |
| CENPS-CORT | CENPS-CORT readthrough | -2.3326 |
| MRPL12 | mitochondrial ribosomal protein L12 | -2.32431 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | -2.32242 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | -2.31635 |
| CETN2 | centrin, EF-hand protein, 2 | -2.31379 |
| PIERCE1 | piercer of microtubule wall 1 | -2.31176 |
| NUP93 | nucleoporin 93kDa | -2.30925 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | -2.30284 |
| CEP76 | centrosomal protein 76kDa | -2.30274 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | -2.30256 |
| RRM2 | ribonucleotide reductase M2 | -2.30165 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -2.29849 |
| CDK2 | cyclin-dependent kinase 2 | -2.27837 |
| CENPA | centromere protein A | -2.2754 |
| SNRPD3 | small nuclear ribonucleoprotein D3 polypeptide 18kDa | -2.26792 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -2.25702 |
| IFT81 | intraflagellar transport 81 | -2.23176 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) | -2.2202 |
| PDZK1 | PDZ domain containing 1 | -2.21456 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | -2.20841 |
| TMEM106C | transmembrane protein 106C | -2.19907 |
| CDCA3 | cell division cycle associated 3 | -2.19231 |
| SHCBP1 | SHC SH2-domain binding protein 1 | -2.18859 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 | -2.18522 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -2.17881 |
| SPDEF | SAM pointed domain containing ETS transcription factor | -2.1769 |
| TROAP | trophinin associated protein | -2.16655 |
| ZNF200 | zinc finger protein 200 | -2.16493 |
| ERI2 | ERI1 exoribonuclease family member 2 | -2.16096 |
| MFF | mitochondrial fission factor | -2.15679 |
| DTYMK | deoxythymidylate kinase (thymidylate kinase) | -2.15562 |
| GCH1 | GTP cyclohydrolase 1 | -2.15486 |
| CENPM | centromere protein M | -2.15227 |
| COLGALT1 | collagen beta(1-O)galactosyltransferase 1 | -2.14409 |
| TIMM8A | translocase of inner mitochondrial membrane 8 homolog A (yeast) | -2.14111 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | -2.13628 |
| EIF4EBP2 | eukaryotic translation initiation factor 4E binding protein 2 | -2.13511 |
| RBM14-RBM4 | RBM14-RBM4 readthrough | -2.12897 |
| DHCR7 | 7-dehydrocholesterol reductase | -2.1287 |
| CA8 | carbonic anhydrase VIII | -2.12472 |
| CEP192 | centrosomal protein 192kDa | -2.12469 |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) | -2.11744 |
| CDK4 | cyclin-dependent kinase 4 | -2.11734 |
| FASTKD3 | FAST kinase domains 3 | -2.11729 |
| CHAF1A | chromatin assembly factor 1, subunit A (p150) | -2.11581 |
| GLT8D1 | glycosyltransferase 8 domain containing 1 | -2.11521 |
| SNAPC4 | small nuclear RNA activating complex, polypeptide 4, 190kDa | -2.11275 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | -2.10963 |
| TERT | telomerase reverse transcriptase | -2.10452 |
| POLD1 | polymerase (DNA directed), delta 1, catalytic subunit | -2.10324 |
| GPC3 | glypican 3 | -2.10106 |
| PMPCA | peptidase (mitochondrial processing) alpha | -2.10014 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -2.09717 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.09581 |
| WDR77 | WD repeat domain 77 | -2.0942 |
| FANCI | Fanconi anemia, complementation group I | -2.08989 |
| HMGB2 | high mobility group box 2 | -2.08946 |
| CELSR2 | cadherin, EGF LAG seven-pass G-type receptor 2 | -2.08824 |
| MRPL16 | mitochondrial ribosomal protein L16 | -2.08573 |
| INCENP | inner centromere protein antigens 135/155kDa | -2.08535 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -2.08332 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -2.0818 |
| GINS3 | GINS complex subunit 3 (Psf3 homolog) | -2.0777 |
| CHERP | calcium homeostasis endoplasmic reticulum protein | -2.07357 |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial | -2.07291 |
| LSM3 | LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.06686 |
| RHCG | Rh family, C glycoprotein | -2.06461 |
| ARHGAP19 | Rho GTPase activating protein 19 | -2.05983 |
| UNC119 | unc-119 homolog (C. elegans) | -2.05856 |
| RNASE7 | ribonuclease, RNase A family, 7 | -2.05705 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -2.05579 |
| FUS | FUS RNA binding protein | -2.05252 |
| AAMP | angio-associated, migratory cell protein | -2.04974 |
| PYCR3 | pyrroline-5-carboxylate reductase 3 | -2.04919 |
| OIP5 | Opa interacting protein 5 | -2.04548 |
| FAM111A | family with sequence similarity 111, member A | -2.03827 |
| THOP1 | thimet oligopeptidase 1 | -2.03131 |
| BMP4 | bone morphogenetic protein 4 | -2.0295 |
| NEK4 | NIMA-related kinase 4 | -2.02939 |
| PAXIP1 | PAX interacting (with transcription-activation domain) protein 1 | -2.02795 |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 | -2.02606 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | -2.02467 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | -2.01773 |
| VKORC1 | vitamin K epoxide reductase complex, subunit 1 | -2.01516 |
| DONSON | downstream neighbor of SON | -2.01336 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | -2.01319 |
| URM1 | ubiquitin related modifier 1 | -2.01305 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | -2.01271 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -2.00748 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -2.00198 |
