CRCGN012_HEPG2_24H:K03 Gene Set
Genes
43 genes differentially expressed following the CRCGN012_HEPG2_24H:K03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
GSTZ1
|
glutathione S-transferase zeta 1
|
7.31324
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
6.80971
|
|
CSK
|
c-src tyrosine kinase
|
6.32682
|
|
STK10
|
serine/threonine kinase 10
|
6.25284
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
5.38416
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.74236
|
|
CBR1
|
carbonyl reductase 1
|
4.722
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
4.7138
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
4.09941
|
|
RRAGA
|
Ras-related GTP binding A
|
3.75751
|
|
E2F2
|
E2F transcription factor 2
|
3.55396
|
|
JADE2
|
jade family PHD finger 2
|
3.26136
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
3.10044
|
|
PIP4K2B
|
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
|
3.04973
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.03351
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.01389
|
|
CHN1
|
chimerin 1
|
2.98794
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.84483
|
|
ZNF589
|
zinc finger protein 589
|
2.67503
|
|
CCNF
|
cyclin F
|
2.66744
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
2.53467
|
|
FZD7
|
frizzled class receptor 7
|
2.42343
|
|
CEP57
|
centrosomal protein 57kDa
|
2.41217
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.19302
|
|
PCDHB11
|
protocadherin beta 11
|
2.00512
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-5.29146
|
|
VAT1
|
vesicle amine transport 1
|
-4.93029
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.72164
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.4754
|
|
CTSD
|
cathepsin D
|
-3.52408
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.23762
|
|
LDHD
|
lactate dehydrogenase D
|
-3.23075
|
|
PEG10
|
paternally expressed 10
|
-3.03824
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-3.01219
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.00408
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.95782
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.93573
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.64909
|
|
TES
|
testin LIM domain protein
|
-2.56834
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.44426
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
-2.16398
|
|
RAI14
|
retinoic acid induced 14
|
-2.15829
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.09365
|
