CRCGN012_HEPG2_24H:K04 Gene Set
Genes
50 genes differentially expressed following the CRCGN012_HEPG2_24H:K04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
6.06117
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
6.02832
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.43725
|
|
E2F2
|
E2F transcription factor 2
|
4.29726
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.92233
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
3.5027
|
|
CGRRF1
|
cell growth regulator with ring finger domain 1
|
3.47235
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.456
|
|
TAC4
|
tachykinin 4 (hemokinin)
|
3.45261
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
3.39693
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
3.35809
|
|
BTK
|
Bruton agammaglobulinemia tyrosine kinase
|
3.29559
|
|
EPHA3
|
EPH receptor A3
|
3.20418
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.65461
|
|
VGLL4
|
vestigial-like family member 4
|
2.60581
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.34647
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
2.24312
|
|
NOTCH1
|
notch 1
|
2.22933
|
|
HYOU1
|
hypoxia up-regulated 1
|
2.20828
|
|
STAG3
|
stromal antigen 3
|
2.1963
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.19326
|
|
MEST
|
mesoderm specific transcript
|
2.14534
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.14529
|
|
BIRC7
|
baculoviral IAP repeat containing 7
|
2.09924
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
2.05877
|
|
PMM2
|
phosphomannomutase 2
|
2.0339
|
|
PRR15L
|
proline rich 15-like
|
2.00771
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-5.74491
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-4.56758
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-4.55711
|
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
-4.15126
|
|
LDHD
|
lactate dehydrogenase D
|
-4.0525
|
|
EGF
|
epidermal growth factor
|
-3.9306
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.87151
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.34508
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.33085
|
|
LAP3
|
leucine aminopeptidase 3
|
-3.28009
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.08706
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.07207
|
|
PEG10
|
paternally expressed 10
|
-2.65046
|
|
SNX11
|
sorting nexin 11
|
-2.50811
|
|
GNAS
|
GNAS complex locus
|
-2.48612
|
|
GTF2E2
|
general transcription factor IIE, polypeptide 2, beta 34kDa
|
-2.41424
|
|
P2RX5
|
purinergic receptor P2X, ligand gated ion channel, 5
|
-2.3515
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.29848
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-2.28175
|
|
GLOD4
|
glyoxalase domain containing 4
|
-2.14095
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.0569
|
|
EIF1B
|
eukaryotic translation initiation factor 1B
|
-2.05319
|
|
ZNF586
|
zinc finger protein 586
|
-2.03619
|
