| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2-chloroacetophenone 1.26 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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66 genes differentially expressed following the CRCGN012_HEPG2_24H:K06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| E2F2 | E2F transcription factor 2 | 5.6474 |
| CHN1 | chimerin 1 | 4.80264 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.48854 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.4527 |
| ANO10 | anoctamin 10 | 3.73448 |
| AMDHD2 | amidohydrolase domain containing 2 | 3.65588 |
| ATP11B | ATPase, class VI, type 11B | 3.58642 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.13773 |
| STK10 | serine/threonine kinase 10 | 3.00084 |
| TEX10 | testis expressed 10 | 2.9926 |
| CCNF | cyclin F | 2.92306 |
| SATB1 | SATB homeobox 1 | 2.77894 |
| KDM5A | lysine (K)-specific demethylase 5A | 2.76204 |
| CSK | c-src tyrosine kinase | 2.74554 |
| MEST | mesoderm specific transcript | 2.73347 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 2.6396 |
| ADRB2 | adrenoceptor beta 2, surface | 2.60905 |
| EPN2 | epsin 2 | 2.59306 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.5549 |
| CCDC85B | coiled-coil domain containing 85B | 2.54216 |
| HEBP1 | heme binding protein 1 | 2.52293 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.50754 |
| PIH1D1 | PIH1 domain containing 1 | 2.37559 |
| CYCS | cytochrome c, somatic | 2.37369 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.35078 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 2.27217 |
| EPHB2 | EPH receptor B2 | 2.26178 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 2.24643 |
| PRR15L | proline rich 15-like | 2.21401 |
| PRRC1 | proline-rich coiled-coil 1 | 2.18128 |
| CDK6 | cyclin-dependent kinase 6 | 2.16969 |
| VGLL4 | vestigial-like family member 4 | 2.09051 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 2.07941 |
| MAMLD1 | mastermind-like domain containing 1 | 2.05039 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.04897 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.03272 |
| GATA3 | GATA binding protein 3 | 2.02278 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.00905 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -5.63054 |
| UGDH | UDP-glucose 6-dehydrogenase | -4.43194 |
| ZNF586 | zinc finger protein 586 | -4.18384 |
| SLC35F2 | solute carrier family 35, member F2 | -4.01674 |
| LDHD | lactate dehydrogenase D | -3.83119 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.82832 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.76174 |
| SPAG4 | sperm associated antigen 4 | -3.64942 |
| SNX11 | sorting nexin 11 | -3.53667 |
| ANKRD10 | ankyrin repeat domain 10 | -3.41122 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -3.3562 |
| RGS2 | regulator of G-protein signaling 2 | -3.33557 |
| CD320 | CD320 molecule | -3.14939 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.83673 |
| VDAC1 | voltage-dependent anion channel 1 | -2.59886 |
| ADI1 | acireductone dioxygenase 1 | -2.53363 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -2.24107 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -2.20776 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.20003 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -2.14029 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | -2.11854 |
| VPS45 | vacuolar protein sorting 45 homolog (S. cerevisiae) | -2.09949 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.07727 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 | -2.07636 |
| MARCHF2 | membrane associated ring-CH-type finger 2 | -2.068 |
| GET1 | guided entry of tail-anchored proteins factor 1 | -2.02875 |
| GNAS | GNAS complex locus | -2.0201 |
| CCNB2 | cyclin B2 | -2.00526 |
