CRCGN012_HEPG2_24H:K10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description vorinostat 2.5 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

957 genes differentially expressed following the CRCGN012_HEPG2_24H:K10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 10.0
FOXO4 forkhead box O4 10.0
DNM1 dynamin 1 9.7924
CGRRF1 cell growth regulator with ring finger domain 1 8.06834
TAC4 tachykinin 4 (hemokinin) 7.95658
CBR1 carbonyl reductase 1 7.91104
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 7.89953
STX1A syntaxin 1A (brain) 7.64082
UBE2L6 ubiquitin-conjugating enzyme E2L 6 7.60605
H2BC12 H2B clustered histone 12 7.11279
CSK c-src tyrosine kinase 7.08152
ALDOC aldolase C, fructose-bisphosphate 7.05799
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 6.82392
PLA2G15 phospholipase A2, group XV 6.79754
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 6.33485
CARMIL1 capping protein regulator and myosin 1 linker 1 6.24641
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 5.98097
ZDHHC6 zinc finger, DHHC-type containing 6 5.9677
DUSP6 dual specificity phosphatase 6 5.82744
GSTZ1 glutathione S-transferase zeta 1 5.7456
MYC v-myc avian myelocytomatosis viral oncogene homolog 5.64738
LGMN legumain 5.63072
TCEA2 transcription elongation factor A (SII), 2 5.51908
PRKCD protein kinase C, delta 5.50253
AMDHD2 amidohydrolase domain containing 2 5.3995
NIT1 nitrilase 1 5.30428
ARFIP2 ADP-ribosylation factor interacting protein 2 5.17498
INTS3 integrator complex subunit 3 5.03967
MVP major vault protein 4.95315
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 4.93095
COG7 component of oligomeric golgi complex 7 4.80723
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 4.77124
ABHD4 abhydrolase domain containing 4 4.66313
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 4.60454
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 4.51678
DYNLT3 dynein, light chain, Tctex-type 3 4.43616
CCND3 cyclin D3 4.41783
TMEM50A transmembrane protein 50A 4.41185
STXBP2 syntaxin binding protein 2 4.36508
TIMP2 TIMP metallopeptidase inhibitor 2 4.25564
CNPY4 canopy FGF signaling regulator 4 4.20023
NOTCH1 notch 1 4.18853
PPP1R13B protein phosphatase 1, regulatory subunit 13B 4.14556
SKIC2 SKI2 subunit of superkiller complex 4.1288
GFOD1 glucose-fructose oxidoreductase domain containing 1 4.12015
BAMBI BMP and activin membrane-bound inhibitor 4.05103
TBC1D10C TBC1 domain family, member 10C 4.03198
ATG2A autophagy related 2A 3.99489
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 3.92964
TIAM1 T-cell lymphoma invasion and metastasis 1 3.91534
GPR162 G protein-coupled receptor 162 3.90864
SYNE2 spectrin repeat containing, nuclear envelope 2 3.88761
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 3.8367
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 3.83203
CCDC71 coiled-coil domain containing 71 3.82658
HLA-DMA major histocompatibility complex, class II, DM alpha 3.77454
CIAO3 cytosolic iron-sulfur assembly component 3 3.75403
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 3.75113
ZNF646 zinc finger protein 646 3.70924
BBC3 BCL2 binding component 3 3.70395
PPARD peroxisome proliferator-activated receptor delta 3.69867
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 3.68917
TWF2 twinfilin actin binding protein 2 3.68332
MCOLN1 mucolipin 1 3.67993
NUCB2 nucleobindin 2 3.6777
PTPN1 protein tyrosine phosphatase, non-receptor type 1 3.66297
STK10 serine/threonine kinase 10 3.64489
TBPL1 TBP-like 1 3.59995
CYB561 cytochrome b561 3.58831
TCEAL4 transcription elongation factor A (SII)-like 4 3.56683
USP6NL USP6 N-terminal like 3.55765
NPDC1 neural proliferation, differentiation and control, 1 3.5349
NCOA3 nuclear receptor coactivator 3 3.52112
ELAVL3 ELAV like neuron-specific RNA binding protein 3 3.51147
DYNC2I1 dynein 2 intermediate chain 1 3.44187
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.43909
KCTD17 potassium channel tetramerization domain containing 17 3.42729
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 3.4225
GRN granulin 3.35731
SHARPIN SHANK-associated RH domain interactor 3.35349
PNKP polynucleotide kinase 3'-phosphatase 3.3519
CCDC92 coiled-coil domain containing 92 3.35179
LSR lipolysis stimulated lipoprotein receptor 3.34035
HABP4 hyaluronan binding protein 4 3.33896
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 3.33628
GIPR gastric inhibitory polypeptide receptor 3.32589
RPL39L ribosomal protein L39-like 3.32387
SPI1 Spi-1 proto-oncogene 3.32177
TERF2IP telomeric repeat binding factor 2, interacting protein 3.31661
AARS1 alanyl-tRNA synthetase 1 3.31483
FGD6 FYVE, RhoGEF and PH domain containing 6 3.30764
MALT1 MALT1 paracaspase 3.30184
CALM3 calmodulin 3 (phosphorylase kinase, delta) 3.29972
PLCH2 phospholipase C, eta 2 3.2882
RSU1 Ras suppressor protein 1 3.24085
DENND2D DENN/MADD domain containing 2D 3.23364
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C 3.23088
HMOX1 heme oxygenase 1 3.22503
SETD1A SET domain containing 1A 3.20896
ZNG1A Zn regulated GTPase metalloprotein activator 1A 3.18736
RBKS ribokinase 3.18228
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 3.17857
SYP synaptophysin 3.174
CXCR4 chemokine (C-X-C motif) receptor 4 3.15995
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 3.15449
CELF3 CUGBP, Elav-like family member 3 3.14832
BORCS6 BLOC-1 related complex subunit 6 3.14774
TMEM121 transmembrane protein 121 3.12253
KIF5C kinesin family member 5C 3.12214
UBE3C ubiquitin protein ligase E3C 3.12142
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome 3.11991
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 3.11252
ABHD6 abhydrolase domain containing 6 3.11106
FRMD4B FERM domain containing 4B 3.10519
ARMCX4 armadillo repeat containing, X-linked 4 3.09818
H2BC21 H2B clustered histone 21 3.09558
PHKG2 phosphorylase kinase, gamma 2 (testis) 3.09179
TXNRD1 thioredoxin reductase 1 3.09048
YPEL5 yippee-like 5 (Drosophila) 3.07367
CATSPER2 cation channel, sperm associated 2 3.07223
ANO10 anoctamin 10 3.06345
PLCL1 phospholipase C-like 1 3.05488
LRP10 low density lipoprotein receptor-related protein 10 3.04779
WDR44 WD repeat domain 44 3.04515
IQCC IQ motif containing C 3.04222
TLE6 transducin-like enhancer of split 6 3.03978
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 3.03825
MAGEH1 melanoma antigen family H1 3.03641
CAB39 calcium binding protein 39 3.03371
GSDMB gasdermin B 3.02922
GOLGB1 golgin B1 3.02754
BACE2 beta-site APP-cleaving enzyme 2 3.0251
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 3.02487
ALAS1 5'-aminolevulinate synthase 1 3.02332
TRAPPC14 trafficking protein particle complex subunit 14 3.01999
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 3.00707
INPP1 inositol polyphosphate-1-phosphatase 2.99696
IGFBP3 insulin-like growth factor binding protein 3 2.99072
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 2.98887
TRAPPC6A trafficking protein particle complex 6A 2.96691
ZNF205 zinc finger protein 205 2.96157
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 2.94859
H1-2 H1.2 linker histone, cluster member 2.93512
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 2.933
PPP1R16B protein phosphatase 1, regulatory subunit 16B 2.93214
THEMIS2 thymocyte selection associated family member 2 2.91601
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 2.91386
GPSM3 G-protein signaling modulator 3 2.91137
CYTH1 cytohesin 1 2.90861
TMCO1 transmembrane and coiled-coil domains 1 2.8962
SDK2 sidekick cell adhesion molecule 2 2.88496
STIMATE STIM activating enhancer 2.88482
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 2.86984
ARL3 ADP-ribosylation factor-like 3 2.86582
NMT2 N-myristoyltransferase 2 2.86567
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.84603
BIN3 bridging integrator 3 2.83011
MAPK3 mitogen-activated protein kinase 3 2.82646
TCF15 transcription factor 15 (basic helix-loop-helix) 2.80968
CYCS cytochrome c, somatic 2.80351
DOC2A double C2-like domains, alpha 2.79954
PCDHA9 protocadherin alpha 9 2.79355
DTX2 deltex 2, E3 ubiquitin ligase 2.79327
SYT12 synaptotagmin XII 2.79162
GLRX glutaredoxin (thioltransferase) 2.7908
CASP9 caspase 9, apoptosis-related cysteine peptidase 2.78947
GAL3ST4 galactose-3-O-sulfotransferase 4 2.78439
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 2.78382
FBXO2 F-box protein 2 2.78123
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 2.78059
ANO2 anoctamin 2, calcium activated chloride channel 2.779
GABARAPL2 GABA(A) receptor-associated protein-like 2 2.77868
DOK4 docking protein 4 2.7618
PLPPR2 phospholipid phosphatase related 2 2.75446
SLC12A9 solute carrier family 12, member 9 2.75038
CARD14 caspase recruitment domain family, member 14 2.74735
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 2.73828
GPR137B G protein-coupled receptor 137B 2.73637
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 2.73034
ROM1 retinal outer segment membrane protein 1 2.72463
USP20 ubiquitin specific peptidase 20 2.72313
LIG4 ligase IV, DNA, ATP-dependent 2.71925
SPIN2A spindlin family, member 2A 2.71245
CFB complement factor B 2.70788
E2F2 E2F transcription factor 2 2.70719
KIAA1614 KIAA1614 2.70685
GPR45 G protein-coupled receptor 45 2.70469
RUBCN rubicon autophagy regulator 2.70453
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 2.70233
NLGN3 neuroligin 3 2.69882
TCAP titin-cap 2.69742
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa 2.69523
NECAP2 NECAP endocytosis associated 2 2.69477
CLDN6 claudin 6 2.69337
CCP110 centriolar coiled coil protein 110kDa 2.67723
COPB2 coatomer protein complex, subunit beta 2 (beta prime) 2.67486
MAST3 microtubule associated serine/threonine kinase 3 2.66899
MUC3B mucin 3B, cell surface associated 2.66742
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 2.66423
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.66143
EFNA3 ephrin-A3 2.65763
UGDH UDP-glucose 6-dehydrogenase 2.65651
GM2A GM2 ganglioside activator 2.65597
MSH5 mutS homolog 5 2.6502
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13 2.64151
RASAL2 RAS protein activator like 2 2.63877
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 2.63461
TRIM62 tripartite motif containing 62 2.63435
UNC93B1 unc-93 homolog B1 (C. elegans) 2.63279
TBXA2R thromboxane A2 receptor 2.63181
ARSF arylsulfatase F 2.63122
LPCAT4 lysophosphatidylcholine acyltransferase 4 2.63025
GBX1 gastrulation brain homeobox 1 2.62732
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 2.62677
PTP4A3 protein tyrosine phosphatase type IVA, member 3 2.62325
PPP4C protein phosphatase 4, catalytic subunit 2.62213
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 2.61608
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 2.61444
PICK1 protein interacting with PRKCA 1 2.61253
EGR1 early growth response 1 2.61105
FABP2 fatty acid binding protein 2, intestinal 2.61038
PARD6A par-6 family cell polarity regulator alpha 2.61029
SLC25A44 solute carrier family 25, member 44 2.60958
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 2.60351
FURIN furin (paired basic amino acid cleaving enzyme) 2.60218
COG2 component of oligomeric golgi complex 2 2.59925
RBM12B RNA binding motif protein 12B 2.59556
NPR1 natriuretic peptide receptor 1 2.59066
HDAC7 histone deacetylase 7 2.58515
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 2.57187
GSTP1 glutathione S-transferase pi 1 2.56747
CLTB clathrin, light chain B 2.56567
RND1 Rho family GTPase 1 2.5647
ALX3 ALX homeobox 3 2.55888
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 2.55655
FUZ fuzzy planar cell polarity protein 2.551
RUNDC3A RUN domain containing 3A 2.5448
ARMCX5-GPRASP2 ARMCX5-GPRASP2 readthrough 2.54126
PLXNB3 plexin B3 2.53188
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 2.53094
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase 2.52878
MYL7 myosin, light chain 7, regulatory 2.52861
AP1B1 adaptor-related protein complex 1, beta 1 subunit 2.52821
PIM2 Pim-2 proto-oncogene, serine/threonine kinase 2.52628
NXPH4 neurexophilin 4 2.52497
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.52361
MUC13 mucin 13, cell surface associated 2.51682
IL10RA interleukin 10 receptor, alpha 2.51616
C15ORF38-AP3S2 C15orf38-AP3S2 readthrough 2.51399
GBA1 glucosylceramidase beta 1 2.5115
SPTBN5 spectrin, beta, non-erythrocytic 5 2.50911
MNAT1 MNAT CDK-activating kinase assembly factor 1 2.50481
TTLL3 tubulin tyrosine ligase-like family member 3 2.50248
HESX1 HESX homeobox 1 2.50191
NR1H2 nuclear receptor subfamily 1, group H, member 2 2.49969
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 2.49912
LTB4R leukotriene B4 receptor 2.49852
IDUA iduronidase, alpha-L- 2.49851
AKAP8 A kinase (PRKA) anchor protein 8 2.49739
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae) 2.49568
ARHGAP25 Rho GTPase activating protein 25 2.49547
ADGRD2 adhesion G protein-coupled receptor D2 2.49445
CAMK1D calcium/calmodulin-dependent protein kinase ID 2.49133
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 2.4898
CORO1A coronin, actin binding protein, 1A 2.48906
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 2.48853
NOSIP nitric oxide synthase interacting protein 2.48412
LTA lymphotoxin alpha 2.48343
NR5A1 nuclear receptor subfamily 5, group A, member 1 2.48318
GCC2 GRIP and coiled-coil domain containing 2 2.47965
ACVR1 activin A receptor, type I 2.47748
ERI3 ERI1 exoribonuclease family member 3 2.47601
MAP7 microtubule-associated protein 7 2.47477
LMF1 lipase maturation factor 1 2.47162
MADD MAP-kinase activating death domain 2.4713
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.47059
ACP5 acid phosphatase 5, tartrate resistant 2.46915
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 2.46745
MDFI MyoD family inhibitor 2.46429
AMPD2 adenosine monophosphate deaminase 2 2.46284
REPS2 RALBP1 associated Eps domain containing 2 2.4626
ACTL8 actin-like 8 2.45883
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 2.45848
CCL2 chemokine (C-C motif) ligand 2 2.4563
RNF167 ring finger protein 167 2.4558
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 2.45504
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 2.45368
MYO9A myosin IXA 2.45326
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 2.45315
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 2.45256
TUBA4A tubulin, alpha 4a 2.44978
CEP290 centrosomal protein 290kDa 2.44663
SH2B1 SH2B adaptor protein 1 2.4447
PRR14 proline rich 14 2.44238
FABP3 fatty acid binding protein 3, muscle and heart 2.44057
TRAFD1 TRAF-type zinc finger domain containing 1 2.43444
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 2.43342
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 2.43251
KIF2C kinesin family member 2C 2.43193
TFEC transcription factor EC 2.42598
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 2.42344
KIFC3 kinesin family member C3 2.42274
TMEM40 transmembrane protein 40 2.42198
LIN37 lin-37 DREAM MuvB core complex component 2.41854
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.41658
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) 2.41647
ZCCHC14 zinc finger, CCHC domain containing 14 2.41381
SPEG SPEG complex locus 2.41213
MSR1 macrophage scavenger receptor 1 2.41
MTNR1B melatonin receptor 1B 2.40918
HTRA1 HtrA serine peptidase 1 2.40806
TM6SF1 transmembrane 6 superfamily member 1 2.40715
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) 2.40557
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 2.40222
ZMYM1 zinc finger, MYM-type 1 2.40196
FAM246A family with sequence similarity 246 member A 2.39896
ICAM1 intercellular adhesion molecule 1 2.39805
H2AC6 H2A clustered histone 6 2.39584
FBXO46 F-box protein 46 2.39342
ZBP1 Z-DNA binding protein 1 2.39044
GIPC1 GIPC PDZ domain containing family, member 1 2.38803
HMG20B high mobility group 20B 2.3851
H2BC4 H2B clustered histone 4 2.38324
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 2.37153
SIX1 SIX homeobox 1 2.37032
ROGDI rogdi homolog (Drosophila) 2.36772
ELL elongation factor RNA polymerase II 2.36631
SH3BP1 SH3-domain binding protein 1 2.36359
TBX4 T-box 4 2.36354
BAX BCL2-associated X protein 2.3631
PLA2R1 phospholipase A2 receptor 1, 180kDa 2.359
AKAP8L A kinase (PRKA) anchor protein 8-like 2.35733
EVX1 even-skipped homeobox 1 2.35599
FKBP6 FK506 binding protein 6, 36kDa 2.35423
VAMP8 vesicle-associated membrane protein 8 2.35401
SGMS1 sphingomyelin synthase 1 2.35096
IL18BP interleukin 18 binding protein 2.34751
ZNF212 zinc finger protein 212 2.3472
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 2.34279
LINC02210-CRHR1 LINC02210-CRHR1 readthrough 2.34033
RNF170 ring finger protein 170 2.33637
PSORS1C1 psoriasis susceptibility 1 candidate 1 2.33476
CRX cone-rod homeobox 2.33472
HCFC2 host cell factor C2 2.3317
CTR9 CTR9, Paf1/RNA polymerase II complex component 2.32679
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) 2.31856
ZFC3H1 zinc finger, C3H1-type containing 2.31572
SIRT4 sirtuin 4 2.3156
SCARB1 scavenger receptor class B, member 1 2.31438
CALHM2 calcium homeostasis modulator 2 2.31339
CLTC clathrin, heavy chain (Hc) 2.31337
UCN urocortin 2.31318
ZFP36 ZFP36 ring finger protein 2.31243
CALCRL calcitonin receptor-like 2.31133
CLCN1 chloride channel, voltage-sensitive 1 2.30924
CCNJL cyclin J-like 2.30871
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 2.3074
BCAS4 breast carcinoma amplified sequence 4 2.30596
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 2.30237
PCDHGB5 protocadherin gamma subfamily B, 5 2.30091
PARP6 poly (ADP-ribose) polymerase family, member 6 2.29973
HIBCH 3-hydroxyisobutyryl-CoA hydrolase 2.29952
KIF16B kinesin family member 16B 2.29901
RUSC2 RUN and SH3 domain containing 2 2.29628
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 2.29581
SEPHS2 selenophosphate synthetase 2 2.2957
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.29484
OPTN optineurin 2.29278
GRWD1 glutamate-rich WD repeat containing 1 2.29143
GJC2 gap junction protein, gamma 2, 47kDa 2.28978
PCDH1 protocadherin 1 2.28969
TMEM63A transmembrane protein 63A 2.28761
BMP7 bone morphogenetic protein 7 2.28595
TM9SF2 transmembrane 9 superfamily member 2 2.28464
HAO2 hydroxyacid oxidase 2 (long chain) 2.2812
CERS4 ceramide synthase 4 2.2795
HPCAL4 hippocalcin like 4 2.27281
H2BC5 H2B clustered histone 5 2.27274
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 2.27011
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 2.2596
LTB lymphotoxin beta (TNF superfamily, member 3) 2.25795
IFNW1 interferon, omega 1 2.25641
EXOSC4 exosome component 4 2.25607
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 2.25342
CRLF3 cytokine receptor-like factor 3 2.25312
GDAP1L1 ganglioside induced differentiation associated protein 1-like 1 2.25182
SIN3B SIN3 transcription regulator family member B 2.25113
USP15 ubiquitin specific peptidase 15 2.25091
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 2.24861
TRIB1 tribbles pseudokinase 1 2.24842
JPH2 junctophilin 2 2.24649
TARBP1 TAR (HIV-1) RNA binding protein 1 2.24547
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 2.24346
FFAR3 free fatty acid receptor 3 2.24272
ZDHHC13 zinc finger, DHHC-type containing 13 2.23918
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2.23778
NFASC neurofascin 2.23707
STAT4 signal transducer and activator of transcription 4 2.23419
CD52 CD52 molecule 2.23377
BCKDK branched chain ketoacid dehydrogenase kinase 2.23318
DKKL1 dickkopf-like 1 2.23056
AMN amnion associated transmembrane protein 2.22971
KANK3 KN motif and ankyrin repeat domains 3 2.22906
ZNF574 zinc finger protein 574 2.22784
ACAD10 acyl-CoA dehydrogenase family, member 10 2.22751
CLEC16A C-type lectin domain family 16, member A 2.22703
NEU2 sialidase 2 (cytosolic sialidase) 2.22675
FAT1 FAT atypical cadherin 1 2.22392
TLK2 tousled-like kinase 2 2.22373
SCAMP5 secretory carrier membrane protein 5 2.22258
IGF1R insulin-like growth factor 1 receptor 2.21927
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase) 2.21926
SSTR2 somatostatin receptor 2 2.21748
UNC13A unc-13 homolog A (C. elegans) 2.21717
STXBP1 syntaxin binding protein 1 2.21697
USP9X ubiquitin specific peptidase 9, X-linked 2.21648
PDZD7 PDZ domain containing 7 2.21528
H2BC17 H2B clustered histone 17 2.21467
ARID4A AT rich interactive domain 4A (RBP1-like) 2.21324
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 2.2121
TOR1B torsin family 1, member B (torsin B) 2.2106
DUX4 double homeobox 4 2.21051
EDC3 enhancer of mRNA decapping 3 2.20908
SH3GL3 SH3-domain GRB2-like 3 2.20876
SOCS2 suppressor of cytokine signaling 2 2.20499
KRT3 keratin 3, type II 2.20371
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 2.20362
ARF3 ADP-ribosylation factor 3 2.2027
TSHZ2 teashirt zinc finger homeobox 2 2.20043
AASS aminoadipate-semialdehyde synthase 2.1992
GET1 guided entry of tail-anchored proteins factor 1 2.19347
FAM110D family with sequence similarity 110, member D 2.19331
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 2.19266
PRR13 proline rich 13 2.1916
PCYOX1L prenylcysteine oxidase 1 like 2.18868
MAN2C1 mannosidase, alpha, class 2C, member 1 2.18809
HPSE heparanase 2.18679
MYCT1 myc target 1 2.18638
TREX2 three prime repair exonuclease 2 2.18372
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 2.18265
ZNF589 zinc finger protein 589 2.18247
ASB6 ankyrin repeat and SOCS box containing 6 2.18226
DSE dermatan sulfate epimerase 2.18151
PPP2R5B protein phosphatase 2, regulatory subunit B', beta 2.18091
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma 2.17615
EFNB1 ephrin-B1 2.1755
FAXDC2 fatty acid hydroxylase domain containing 2 2.17443
KDM3A lysine (K)-specific demethylase 3A 2.17215
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 2.1717
TESPA1 thymocyte expressed, positive selection associated 1 2.17097
OR3A2 olfactory receptor, family 3, subfamily A, member 2 2.16842
ICAM5 intercellular adhesion molecule 5, telencephalin 2.16836
MYL10 myosin, light chain 10, regulatory 2.16792
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 2.16709
ZNF79 zinc finger protein 79 2.16596
SCNN1D sodium channel, non voltage gated 1 delta subunit 2.16589
EPN2 epsin 2 2.16414
GRIA2 glutamate receptor, ionotropic, AMPA 2 2.16397
ASIC4 acid sensing (proton gated) ion channel family member 4 2.16223
TRIM52 tripartite motif containing 52 2.16201
ADGRG1 adhesion G protein-coupled receptor G1 2.16182
SYNDIG1 synapse differentiation inducing 1 2.1611
ANKRD55 ankyrin repeat domain 55 2.16099
TSNAX translin-associated factor X 2.16001
SACK1E scaffolding CK1 anchoring protein E 2.15909
RAB21 RAB21, member RAS oncogene family 2.15876
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 2.15855
DNALI1 dynein, axonemal, light intermediate chain 1 2.15693
SSTR3 somatostatin receptor 3 2.15355
IL36R interleukin 36 receptor 2.1529
MYF5 myogenic factor 5 2.15161
ERCC2 excision repair cross-complementation group 2 2.14176
RASA4 RAS p21 protein activator 4 2.14163
ERBB4 erb-b2 receptor tyrosine kinase 4 2.13473
VWA7 von Willebrand factor A domain containing 7 2.13432
CHGB chromogranin B 2.1306
MAP3K3 mitogen-activated protein kinase kinase kinase 3 2.12966
PAOX polyamine oxidase (exo-N4-amino) 2.12867
VEZT vezatin, adherens junctions transmembrane protein 2.12783
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 2.12778
MXI1 MAX interactor 1, dimerization protein 2.12706
SNAI1 snail family zinc finger 1 2.12684
HUNK hormonally up-regulated Neu-associated kinase 2.12517
ZNF821 zinc finger protein 821 2.12496
DOCK2 dedicator of cytokinesis 2 2.12334
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 2.1229
ACOT8 acyl-CoA thioesterase 8 2.12156
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 2.12072
NOTCH2 notch 2 2.11943
TSC22D4 TSC22 domain family, member 4 2.11788
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 2.11738
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 2.11702
FRS2 fibroblast growth factor receptor substrate 2 2.11648
NRIP2 nuclear receptor interacting protein 2 2.11258
CIC capicua transcriptional repressor 2.1124
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 2.11233
B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 2.11049
RAB3A RAB3A, member RAS oncogene family 2.11007
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1 2.10975
PTAFR platelet-activating factor receptor 2.10669
PCDHA10 protocadherin alpha 10 2.10563
MACO1 macoilin 1 2.1038
DNAAF8 dynein axonemal assembly factor 8 2.10274
AHDC1 AT hook, DNA binding motif, containing 1 2.10262
SYTL2 synaptotagmin-like 2 2.10145
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 2.10085
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 2.09994
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 2.09887
LRP2 low density lipoprotein receptor-related protein 2 2.09839
SCYL3 SCY1-like 3 (S. cerevisiae) 2.09725
SARAF store-operated calcium entry-associated regulatory factor 2.095
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 2.09388
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 2.09342
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) 2.09328
SLAMF1 signaling lymphocytic activation molecule family member 1 2.09284
DACH1 dachshund family transcription factor 1 2.09278
DDB2 damage-specific DNA binding protein 2, 48kDa 2.09089
WBP1L WW domain binding protein 1-like 2.09087
ADRA2B adrenoceptor alpha 2B 2.08839
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.0855
EPHB2 EPH receptor B2 2.08527
ACBD4 acyl-CoA binding domain containing 4 2.08497
BEGAIN brain-enriched guanylate kinase-associated 2.0843
GRB14 growth factor receptor-bound protein 14 2.08417
NME7 NME/NM23 family member 7 2.08254
TBX6 T-box 6 2.07786
CAND2 cullin-associated and neddylation-dissociated 2 (putative) 2.07749
CATSPERB catsper channel auxiliary subunit beta 2.07649
MKNK1 MAP kinase interacting serine/threonine kinase 1 2.07564
SZT2 seizure threshold 2 homolog (mouse) 2.07554
ALOX12B arachidonate 12-lipoxygenase, 12R type 2.07475
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 2.07439
TDRKH tudor and KH domain containing 2.07341
PLK3 polo-like kinase 3 2.07331
OR11A1 olfactory receptor, family 11, subfamily A, member 1 2.07293
KCTD13 potassium channel tetramerization domain containing 13 2.07073
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 2.06977
PIGU phosphatidylinositol glycan anchor biosynthesis, class U 2.06918
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 2.06599
CDH9 cadherin 9, type 2 (T1-cadherin) 2.06292
S1PR5 sphingosine-1-phosphate receptor 5 2.06141
CPLX3 complexin 3 2.06015
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10 2.05997
NACAD NAC alpha domain containing 2.05928
UBE2A ubiquitin-conjugating enzyme E2A 2.05827
TMEM59L transmembrane protein 59-like 2.05392
VAMP4 vesicle-associated membrane protein 4 2.05376
PLXDC2 plexin domain containing 2 2.05297
ULBP2 UL16 binding protein 2 2.05275
CUBN cubilin (intrinsic factor-cobalamin receptor) 2.05138
OSTF1 osteoclast stimulating factor 1 2.05107
INTS5 integrator complex subunit 5 2.04995
CRYGD crystallin, gamma D 2.04846
CLIC5 chloride intracellular channel 5 2.04707
FHIT fragile histidine triad 2.046
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 2.04521
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.04457
CREB3L2 cAMP responsive element binding protein 3-like 2 2.04351
BAZ2A bromodomain adjacent to zinc finger domain, 2A 2.04279
NCR3 natural cytotoxicity triggering receptor 3 2.04199
TRIM45 tripartite motif containing 45 2.04091
BEST1 bestrophin 1 2.04089
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28 2.04084
RIN1 Ras and Rab interactor 1 2.03956
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 2.03932
IQSEC2 IQ motif and Sec7 domain 2 2.03832
CSRNP3 cysteine-serine-rich nuclear protein 3 2.03719
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 2.03555
TGFB1 transforming growth factor, beta 1 2.03547
KHDC4 KH domain containing 4, pre-mRNA splicing factor 2.03285
RBMY1J RNA binding motif protein, Y-linked, family 1, member J 2.03151
CDH22 cadherin 22, type 2 2.03097
ZNF696 zinc finger protein 696 2.03095
PRKCQ protein kinase C, theta 2.0296
CBX4 chromobox homolog 4 2.02944
RBP3 retinol binding protein 3, interstitial 2.02901
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 2.0286
OSGIN1 oxidative stress induced growth inhibitor 1 2.02641
CSNK1G1 casein kinase 1, gamma 1 2.02393
NYX nyctalopin 2.02358
PAIP2B poly(A) binding protein interacting protein 2B 2.0229
MEF2B myocyte enhancer factor 2B 2.02269
B3GALT5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 2.02166
GNB5 guanine nucleotide binding protein (G protein), beta 5 2.01883
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 2.01808
ZNF362 zinc finger protein 362 2.01714
CDA cytidine deaminase 2.01649
EXOC6B exocyst complex component 6B 2.01374
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 2.01357
YIPF2 Yip1 domain family, member 2 2.01225
NOX5 NADPH oxidase, EF-hand calcium binding domain 5 2.0117
ADGRL1 adhesion G protein-coupled receptor L1 2.00847
JUP junction plakoglobin 2.00837
PGF placental growth factor 2.00798
TUBG2 tubulin, gamma 2 2.00744
TRDMT1 tRNA aspartic acid methyltransferase 1 2.00741
SCRN3 secernin 3 2.00696
OXCT2 3-oxoacid CoA transferase 2 2.00649
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic) 2.00571
OPN1SW opsin 1 (cone pigments), short-wave-sensitive 2.00547
FOXC1 forkhead box C1 2.00366
DOHH deoxyhypusine hydroxylase/monooxygenase 2.00111
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 2.00047
FBXO22 F-box protein 22 2.00027

decreased expression

Symbol Name Standardized Value
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -9.93391
SLC35F2 solute carrier family 35, member F2 -9.41382
ADI1 acireductone dioxygenase 1 -8.86986
CD320 CD320 molecule -8.81308
RPIA ribose 5-phosphate isomerase A -8.74684
PGM1 phosphoglucomutase 1 -8.73203
TCTN1 tectonic family member 1 -8.40259
KEAP1 kelch-like ECH-associated protein 1 -8.23981
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -7.9999
CRELD2 cysteine-rich with EGF-like domains 2 -7.78551
FAIM Fas apoptotic inhibitory molecule -7.72759
TRIB3 tribbles pseudokinase 3 -7.63851
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -7.5614
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -7.43158
PCCB propionyl CoA carboxylase, beta polypeptide -7.40687
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -7.27237
LOC124907782 dual specificity protein phosphatase 22 -7.25585
TATDN2 TatD DNase domain containing 2 -7.01514
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -6.87914
TMEM109 transmembrane protein 109 -6.79574
PLK1 polo-like kinase 1 -6.72339
NUP85 nucleoporin 85kDa -6.51345
CCNA2 cyclin A2 -6.44808
ZW10 zw10 kinetochore protein -6.22099
FOSL1 FOS-like antigen 1 -6.00825
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -5.94002
CCDC86 coiled-coil domain containing 86 -5.85012
HMGA2 high mobility group AT-hook 2 -5.73651
TCERG1 transcription elongation regulator 1 -5.72165
SOAT2 sterol O-acyltransferase 2 -5.71241
STAP2 signal transducing adaptor family member 2 -5.68061
NNT nicotinamide nucleotide transhydrogenase -5.6706
CASP7 caspase 7, apoptosis-related cysteine peptidase -5.64566
RRAGA Ras-related GTP binding A -5.63495
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -5.60925
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -5.51614
PECR peroxisomal trans-2-enoyl-CoA reductase -5.51396
DCTD dCMP deaminase -5.49578
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -5.37321
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -5.36895
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -5.20559
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -5.1902
CDK1 cyclin-dependent kinase 1 -5.17221
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -5.16767
MELK maternal embryonic leucine zipper kinase -5.14086
ISOC1 isochorismatase domain containing 1 -5.10293
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -5.07584
ECH1 enoyl CoA hydratase 1, peroxisomal -5.05231
ATF5 activating transcription factor 5 -4.98417
DNM1L dynamin 1-like -4.77949
PHF2 PHD finger protein 2 -4.71643
LRRC41 leucine rich repeat containing 41 -4.71438
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -4.71212
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -4.70381
ETFB electron-transfer-flavoprotein, beta polypeptide -4.67616
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -4.64829
NT5DC2 5'-nucleotidase domain containing 2 -4.55425
TSPAN4 tetraspanin 4 -4.55264
TM9SF3 transmembrane 9 superfamily member 3 -4.52681
UBE2C ubiquitin-conjugating enzyme E2C -4.51027
MRPS16 mitochondrial ribosomal protein S16 -4.49916
GTPBP8 GTP-binding protein 8 (putative) -4.46852
CDK4 cyclin-dependent kinase 4 -4.44788
TMEM97 transmembrane protein 97 -4.40955
BDH1 3-hydroxybutyrate dehydrogenase, type 1 -4.39452
TLCD3A TLC domain containing 3A -4.32562
ICAM3 intercellular adhesion molecule 3 -4.31447
MAPK13 mitogen-activated protein kinase 13 -4.3112
ITGB5 integrin, beta 5 -4.2637
GLOD4 glyoxalase domain containing 4 -4.2464
ELAC2 elaC ribonuclease Z 2 -4.21434
RCC1L RCC1 like -4.1822
SPAG7 sperm associated antigen 7 -4.17037
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -4.11859
AURKB aurora kinase B -4.11052
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 -4.04644
FOXM1 forkhead box M1 -4.03185
CHEK1 checkpoint kinase 1 -3.9155
CDC25A cell division cycle 25A -3.90061
PUF60 poly-U binding splicing factor 60KDa -3.88595
STAMBP STAM binding protein -3.87507
CCNB2 cyclin B2 -3.8325
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -3.82311
AURKA aurora kinase A -3.81723
CTSL cathepsin L -3.79902
CDC45 cell division cycle 45 -3.768
DERA deoxyribose-phosphate aldolase (putative) -3.75177
MRPS2 mitochondrial ribosomal protein S2 -3.72411
ZBTB35 zinc finger and BTB domain containing 35 -3.71762
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.69453
EXOSC8 exosome component 8 -3.62598
GDF15 growth differentiation factor 15 -3.56633
COPS7A COP9 signalosome subunit 7A -3.53367
RAP1GAP RAP1 GTPase activating protein -3.51324
FBXO5 F-box protein 5 -3.49388
ANXA7 annexin A7 -3.47732
NUP62 nucleoporin 62kDa -3.45004
TPM1 tropomyosin 1 (alpha) -3.44528
KLHL21 kelch-like family member 21 -3.44245
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -3.42206
NUP54 nucleoporin 54kDa -3.36614
ENOPH1 enolase-phosphatase 1 -3.36146
SPC25 SPC25, NDC80 kinetochore complex component -3.36006
CRYZ crystallin, zeta (quinone reductase) -3.34896
MYLK myosin light chain kinase -3.34076
SREK1 splicing regulatory glutamine/lysine-rich protein 1 -3.31251
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -3.30673
GNPDA1 glucosamine-6-phosphate deaminase 1 -3.29532
NUP88 nucleoporin 88kDa -3.26025
HJURP Holliday junction recognition protein -3.23064
RPS4Y1 ribosomal protein S4, Y-linked 1 -3.20374
CDCA3 cell division cycle associated 3 -3.2018
GBE1 glucan (1,4-alpha-), branching enzyme 1 -3.17668
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -3.14404
FANCG Fanconi anemia, complementation group G -3.13975
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 -3.13592
FBXO7 F-box protein 7 -3.11725
UFC1 ubiquitin-fold modifier conjugating enzyme 1 -3.10455
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 -3.08623
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites -3.0845
C2CD2 C2 calcium-dependent domain containing 2 -3.0829
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -3.07921
SKA1 spindle and kinetochore associated complex subunit 1 -3.06822
SLC35B1 solute carrier family 35, member B1 -3.06371
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -3.0572
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -3.03864
DSG2 desmoglein 2 -3.01244
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor -2.97868
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -2.96806
BIRC5 baculoviral IAP repeat containing 5 -2.96452
HADH hydroxyacyl-CoA dehydrogenase -2.95332
CYREN cell cycle regulator of NHEJ -2.94036
CRTAP cartilage associated protein -2.92654
TTK TTK protein kinase -2.91849
ACOT2 acyl-CoA thioesterase 2 -2.88405
NEIL3 nei endonuclease VIII-like 3 (E. coli) -2.83421
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.83187
POLR1G RNA polymerase I subunit G -2.8086
PSAT1 phosphoserine aminotransferase 1 -2.80415
PPP1R8 protein phosphatase 1, regulatory subunit 8 -2.79802
GALE UDP-galactose-4-epimerase -2.78925
TFDP1 transcription factor Dp-1 -2.78788
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 -2.78508
RFC3 replication factor C (activator 1) 3, 38kDa -2.781
TTC19 tetratricopeptide repeat domain 19 -2.77518
MICALL1 MICAL-like 1 -2.77308
USP22 ubiquitin specific peptidase 22 -2.76931
TRIP13 thyroid hormone receptor interactor 13 -2.76345
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -2.74221
HEBP1 heme binding protein 1 -2.72792
MRPL23 mitochondrial ribosomal protein L23 -2.72601
DAZAP1 DAZ associated protein 1 -2.72462
MRPL19 mitochondrial ribosomal protein L19 -2.70151
KIF15 kinesin family member 15 -2.70007
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -2.69714
CDC6 cell division cycle 6 -2.69513
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -2.69124
SCMH1 sex comb on midleg homolog 1 (Drosophila) -2.69044
ASGR2 asialoglycoprotein receptor 2 -2.6755
SENP6 SUMO1/sentrin specific peptidase 6 -2.66902
MSRA methionine sulfoxide reductase A -2.66632
DUS1L dihydrouridine synthase 1-like (S. cerevisiae) -2.66535
DBF4 DBF4 zinc finger -2.64967
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial -2.64776
SOX4 SRY (sex determining region Y)-box 4 -2.64661
BARD1 BRCA1 associated RING domain 1 -2.64174
TEAD4 TEA domain family member 4 -2.63098
DPP3 dipeptidyl-peptidase 3 -2.62017
NCAPH non-SMC condensin I complex, subunit H -2.61875
SPAG4 sperm associated antigen 4 -2.61168
MYO19 myosin XIX -2.60644
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.5884
TIMCC TIM double twin CX3C motif chaperone -2.58732
TIMELESS timeless circadian clock -2.58306
LMNB1 lamin B1 -2.58091
RAD51AP1 RAD51 associated protein 1 -2.57827
TSPAN6 tetraspanin 6 -2.57405
NDC80 NDC80 kinetochore complex component -2.57344
POLK polymerase (DNA directed) kappa -2.57094
CAPNS1 calpain, small subunit 1 -2.56445
NCK2 NCK adaptor protein 2 -2.55338
SPDEF SAM pointed domain containing ETS transcription factor -2.54366
OXA1L oxidase (cytochrome c) assembly 1-like -2.52937
SMC4 structural maintenance of chromosomes 4 -2.51933
LYRM1 LYR motif containing 1 -2.5173
NSD2 nuclear receptor binding SET domain protein 2 -2.51432
EXO1 exonuclease 1 -2.51327
OXCT1 3-oxoacid CoA transferase 1 -2.5065
TERT telomerase reverse transcriptase -2.49351
DEPDC1 DEP domain containing 1 -2.49125
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 -2.49039
SDAD1 SDA1 domain containing 1 -2.47617
MTMR2 myotubularin related protein 2 -2.45713
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -2.45171
LDHD lactate dehydrogenase D -2.45053
IPO5 importin 5 -2.44243
CHAF1B chromatin assembly factor 1, subunit B (p60) -2.4394
SMN2 survival of motor neuron 2, centromeric -2.43671
FXN frataxin -2.43436
CHAF1A chromatin assembly factor 1, subunit A (p150) -2.43328
RPH3AL rabphilin 3A-like (without C2 domains) -2.42776
HRAS Harvey rat sarcoma viral oncogene homolog -2.42634
AHSG alpha-2-HS-glycoprotein -2.42298
CDT1 chromatin licensing and DNA replication factor 1 -2.42279
AKT1 v-akt murine thymoma viral oncogene homolog 1 -2.41442
CENPA centromere protein A -2.40155
MRPL12 mitochondrial ribosomal protein L12 -2.39765
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase -2.39728
GTPBP6 GTP binding protein 6 (putative) -2.39714
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing -2.39667
ZBED1 zinc finger, BED-type containing 1 -2.39283
IRAK1 interleukin-1 receptor-associated kinase 1 -2.38525
ACAA1 acetyl-CoA acyltransferase 1 -2.37733
PPIE peptidylprolyl isomerase E (cyclophilin E) -2.37575
IFRD2 interferon-related developmental regulator 2 -2.37268
MCM10 minichromosome maintenance complex component 10 -2.36836
B4GAT1 beta-1,4-glucuronyltransferase 1 -2.36681
MRPS7 mitochondrial ribosomal protein S7 -2.36561
SCCPDH saccharopine dehydrogenase (putative) -2.36436
CPNE3 copine III -2.36154
TRAF1 TNF receptor-associated factor 1 -2.35793
CNPY3 canopy FGF signaling regulator 3 -2.357
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.35361
EPCAM epithelial cell adhesion molecule -2.35358
GUF1 GUF1 GTPase homolog (S. cerevisiae) -2.35166
PROS1 protein S (alpha) -2.34905
BIRC2 baculoviral IAP repeat containing 2 -2.34629
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 -2.34185
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase -2.33706
CX3CL1 chemokine (C-X3-C motif) ligand 1 -2.32796
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -2.32158
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 -2.32052
INHBE inhibin, beta E -2.31463
MRPL34 mitochondrial ribosomal protein L34 -2.3125
COL6A2 collagen, type VI, alpha 2 -2.31016
STEAP1 six transmembrane epithelial antigen of the prostate 1 -2.3064
CCDC59 coiled-coil domain containing 59 -2.30366
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa -2.30128
GTSE1 G-2 and S-phase expressed 1 -2.29095
ABT1 activator of basal transcription 1 -2.28943
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) -2.28029
CLUH clustered mitochondria (cluA/CLU1) homolog -2.27909
PXMP2 peroxisomal membrane protein 2, 22kDa -2.27862
RBFA ribosome binding factor A (putative) -2.27441
SHCBP1 SHC SH2-domain binding protein 1 -2.27263
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) -2.27138
TNIP2 TNFAIP3 interacting protein 2 -2.271
HSPD1 heat shock 60kDa protein 1 (chaperonin) -2.26927
PARP2 poly (ADP-ribose) polymerase 2 -2.26672
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -2.262
PIMREG PICALM interacting mitotic regulator -2.25786
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.25521
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 -2.25472
MEX3D mex-3 RNA binding family member D -2.25039
EGF epidermal growth factor -2.24985
MEX3C mex-3 RNA binding family member C -2.24918
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 -2.24558
PLK4 polo-like kinase 4 -2.24074
PTS 6-pyruvoyltetrahydropterin synthase -2.24014
FANCC Fanconi anemia, complementation group C -2.23769
BCL7B B-cell CLL/lymphoma 7B -2.23169
PPIC peptidylprolyl isomerase C (cyclophilin C) -2.23029
ELOVL2 ELOVL fatty acid elongase 2 -2.23021
KIF11 kinesin family member 11 -2.22993
CNOT9 CCR4-NOT transcription complex subunit 9 -2.22966
GLDC glycine dehydrogenase (decarboxylating) -2.22218
FAM174C family with sequence similarity 174 member C -2.22173
TSKU tsukushi, small leucine rich proteoglycan -2.22138
TMEM33 transmembrane protein 33 -2.2078
ITFG1 integrin alpha FG-GAP repeat containing 1 -2.20495
TPGS2 tubulin polyglutamylase complex subunit 2 -2.20376
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) -2.2027
UFL1 UFM1-specific ligase 1 -2.19978
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -2.19898
RFC2 replication factor C (activator 1) 2, 40kDa -2.19579
ECHDC1 ethylmalonyl-CoA decarboxylase 1 -2.19189
COL4A2 collagen, type IV, alpha 2 -2.16952
APOA2 apolipoprotein A-II -2.1653
RBM14-RBM4 RBM14-RBM4 readthrough -2.16325
TRAP1 TNF receptor-associated protein 1 -2.16304
UBA2 ubiquitin-like modifier activating enzyme 2 -2.16052
POLE polymerase (DNA directed), epsilon, catalytic subunit -2.15859
E2F8 E2F transcription factor 8 -2.1572
TNIP1 TNFAIP3 interacting protein 1 -2.15464
ECT2 epithelial cell transforming 2 -2.15366
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -2.15362
THOC1 THO complex 1 -2.15322
DEAF1 DEAF1 transcription factor -2.15312
RBM15B RNA binding motif protein 15B -2.14967
PHF11 PHD finger protein 11 -2.14739
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.14687
ALG9 ALG9, alpha-1,2-mannosyltransferase -2.14013
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain -2.12876
IGHMBP2 immunoglobulin mu binding protein 2 -2.12638
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -2.12337
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) -2.12177
RXYLT1 ribitol xylosyltransferase 1 -2.11903
FXYD3 FXYD domain containing ion transport regulator 3 -2.11851
PIGK phosphatidylinositol glycan anchor biosynthesis, class K -2.11729
ANAPC15 anaphase promoting complex subunit 15 -2.11645
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -2.1133
SLC25A38 solute carrier family 25, member 38 -2.11093
TUBGCP5 tubulin, gamma complex associated protein 5 -2.10343
MRPL18 mitochondrial ribosomal protein L18 -2.10032
MLH1 mutL homolog 1 -2.09872
SSRP1 structure specific recognition protein 1 -2.09474
SETMAR SET domain and mariner transposase fusion gene -2.09447
SUMO4 small ubiquitin-like modifier 4 -2.09422
ZCCHC8 zinc finger, CCHC domain containing 8 -2.09299
MYDGF myeloid-derived growth factor -2.09087
STX18 syntaxin 18 -2.08567
MGST2 microsomal glutathione S-transferase 2 -2.08517
SYPL1 synaptophysin-like 1 -2.08093
DPH2 DPH2 homolog (S. cerevisiae) -2.08067
THYN1 thymocyte nuclear protein 1 -2.07803
PARPBP PARP1 binding protein -2.07331
ENOSF1 enolase superfamily member 1 -2.07277
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) -2.0717
CCNB1 cyclin B1 -2.06738
SDF4 stromal cell derived factor 4 -2.06694
CEP55 centrosomal protein 55kDa -2.06547
GPRC5C G protein-coupled receptor, class C, group 5, member C -2.06541
ADGRA3 adhesion G protein-coupled receptor A3 -2.06529
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.06479
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 -2.06456
HMMR hyaluronan-mediated motility receptor (RHAMM) -2.06348
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 -2.06008
SCRN1 secernin 1 -2.05858
MRPS30 mitochondrial ribosomal protein S30 -2.05787
EIF5 eukaryotic translation initiation factor 5 -2.05349
ADSS2 adenylosuccinate synthase 2 -2.05313
PFAS phosphoribosylformylglycinamidine synthase -2.04994
TTF2 transcription termination factor, RNA polymerase II -2.04896
ANKRD49 ankyrin repeat domain 49 -2.04618
KIF18B kinesin family member 18B -2.04498
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 -2.03538
MRPL3 mitochondrial ribosomal protein L3 -2.03217
MED17 mediator complex subunit 17 -2.02755
CIRBP cold inducible RNA binding protein -2.02623
PGC progastricsin (pepsinogen C) -2.02606
PROSER1 proline and serine rich 1 -2.02565
CHURC1-FNTB CHURC1-FNTB readthrough -2.02261
HBZ hemoglobin, zeta -2.01819
PGCKA1 PDCD10 and GCKIII kinases associated 1 -2.01803
FASN fatty acid synthase -2.01684
PARP4 poly (ADP-ribose) polymerase family, member 4 -2.01657
SEH1L SEH1-like (S. cerevisiae) -2.01491
OIP5 Opa interacting protein 5 -2.01328
MBNL1 muscleblind-like splicing regulator 1 -2.01205
VCP valosin containing protein -2.01105
PTPN3 protein tyrosine phosphatase, non-receptor type 3 -2.01072
VAV3 vav 3 guanine nucleotide exchange factor -2.00567
QTRT2 queuine tRNA-ribosyltransferase accessory subunit 2 -2.0026