| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | a-1,2,3,4,5,6-hexachlorocyclohexane 20.2 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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73 genes differentially expressed following the CRCGN012_HEPG2_24H:K14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 8.51523 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 5.71883 |
| CHMP6 | charged multivesicular body protein 6 | 5.3076 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 5.2343 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 4.96263 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.68716 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 4.44835 |
| KLHL21 | kelch-like family member 21 | 4.23912 |
| CSK | c-src tyrosine kinase | 4.20106 |
| NOTCH1 | notch 1 | 3.82733 |
| PRR15L | proline rich 15-like | 3.70116 |
| E2F2 | E2F transcription factor 2 | 3.41227 |
| PFKL | phosphofructokinase, liver | 3.39708 |
| AMDHD2 | amidohydrolase domain containing 2 | 3.07863 |
| VGLL4 | vestigial-like family member 4 | 2.93237 |
| NENF | neudesin neurotrophic factor | 2.88014 |
| NOSIP | nitric oxide synthase interacting protein | 2.8421 |
| CYCS | cytochrome c, somatic | 2.69654 |
| GATA3 | GATA binding protein 3 | 2.50192 |
| CEPT1 | choline/ethanolamine phosphotransferase 1 | 2.49106 |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit | 2.44526 |
| TMEM208 | transmembrane protein 208 | 2.29009 |
| WDR4 | WD repeat domain 4 | 2.2733 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.25696 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.25689 |
| HEBP1 | heme binding protein 1 | 2.25494 |
| VAMP5 | vesicle-associated membrane protein 5 | 2.22352 |
| SLC66A2 | solute carrier family 66 member 2 | 2.22301 |
| DHDDS | dehydrodolichyl diphosphate synthase | 2.19113 |
| ICAM1 | intercellular adhesion molecule 1 | 2.1752 |
| TEDC2 | tubulin epsilon and delta complex 2 | 2.17478 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.16849 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | 2.15582 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.14217 |
| PES1 | pescadillo ribosomal biogenesis factor 1 | 2.07943 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.06939 |
| ADM2 | adrenomedullin 2 | 2.05317 |
| CCNF | cyclin F | 2.03558 |
| WASF2 | WAS protein family, member 2 | 2.03081 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -8.16184 |
| LDHD | lactate dehydrogenase D | -5.83379 |
| CDC20 | cell division cycle 20 | -5.47889 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -4.64125 |
| VAT1 | vesicle amine transport 1 | -4.40424 |
| PEG10 | paternally expressed 10 | -4.05163 |
| COG7 | component of oligomeric golgi complex 7 | -3.943 |
| KDM3A | lysine (K)-specific demethylase 3A | -3.91446 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.79555 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -3.7612 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | -3.6958 |
| CHMP4B | charged multivesicular body protein 4B | -3.60392 |
| GNAS | GNAS complex locus | -3.51737 |
| CCNB1 | cyclin B1 | -3.47942 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.36946 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.28288 |
| CDC25B | cell division cycle 25B | -3.24125 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.95593 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -2.80424 |
| SNX11 | sorting nexin 11 | -2.75363 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.71367 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.44811 |
| ZW10 | zw10 kinetochore protein | -2.40358 |
| HOXB13 | homeobox B13 | -2.37178 |
| EGF | epidermal growth factor | -2.35522 |
| PDHX | pyruvate dehydrogenase complex, component X | -2.30851 |
| TGM4 | transglutaminase 4 | -2.29976 |
| MUC16 | mucin 16, cell surface associated | -2.19744 |
| IFT70A | intraflagellar transport 70A | -2.14577 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 | -2.1321 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.12238 |
| ALX1 | ALX homeobox 1 | -2.03779 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.01434 |
| THSD4 | thrombospondin, type I, domain containing 4 | -2.01367 |
